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Recent News and Articles on the Keywords: heart disease + hold clues + gene  Related to the article below (Last Update: 7/1/2008)

Nabbing suspicious SNPs: Scientists search the whole genome for ...
Science News - Jun 6, 2008
Geneticists typically pursued one gene at a time, armed only with guesses?usually wrong?about which chunks of genetic code might be linked to human disease. ...
Famous DEAD Neighbors in San Diego, plus My Brunch With Yoko Ono ...
San Diego Reader, CA - Jun 28, 2008
His murder remains unsolved, though some clues recently studied by the FBI indicate Loren may have had a connection to future serial killer Andrew Cunanan. ...
Television movies for the week of June 8
Pittsburgh Post Gazette, PA - Jun 7, 2008
After learning his memory has been erased, a technical wizard goes on the run to piece together clues from his past. (PG-13) (2:30) TNT: Sat. noon, ...
Source: Google News

… Shareholders in Cardiovascular Disease Enterprises Part III: Cellular and Molecular Clues to Heart -
EG Lakatta - Circulation, 2003 - Am Heart Assoc
... the markedly increased risk for cardiovascular disease in older ... requires an
understanding of heart and arterial ... in these animal models may hold clues that will ...

The New Genomics: Global Views of Biology -
ES Lander - Science, 1996 - sciencemag.org
... levels, risk of thrombosis, heart disease, and resistance ... are also important in
determining disease risk (as ... during development will also hold critical clues ...

Sex Differences in Coronary Heart Disease Why Are Women So Superior? The 1995 Ancel Keys Lecture -
E Barrett-Connor - Circulation, 1997 - Am Heart Assoc
... that family history of premature heart disease is associated ... glucose tolerance are
reminiscent of Cushing's disease. ... in visceral fat distribution hold the key t.

[BOOK] Developmental origins of health and disease -
P Gluckman, M Hanson - 2006 - Springer
... causes of the common chronic diseases of adulthood (heart disease, diabetes, stroke ...
That instead, gene-environment interactions would hold the clues. ...

[CITATION] Coronary artery changes in patients with Kawasaki disease -
RMR Tulloh, LE Wood - Acta Paediatrica, 2004 - Blackwell Synergy
... with KD occurring in clusters and could hold clues as to ... measurement of coronary
flow reserve in children with Kawasaki disease. Heart 2002; 87: 559? 65 21. ...

Coronary heart disease: At the interface of molecular genetics and preventive medicine -
DL Ellsworth, P Sholinsky, C Jaquish, RR Fabsitz, … - American Journal of Preventive Medicine, 1999 - Elsevier
... studies may uncover important clues to understanding ... early stages of development
hold exciting potential ... predisposing individuals to heart disease or aberrant ...

Sex differences in coronary heart disease
E Barrett-Connor - Circulation, 1997 - Am Heart Assoc
... Clues to the gender gap might lie in a ... is a recently rediscovered risk factor for
heart disease. ... European ancestry carry one abnormal gene for hemochromatosis ...

Of Hyperaging and Methuselah Genes -
E Strauss, E Strauss, E Strauss - Science's SAGE KE, 2001 - sageke.sciencemag.org
... It might also provide clues about the normal human aging ... necessary for life because
it helps hold tissue together ... of people who die of heart disease are steeped ...

Metabolic risk factors for coronary heart disease: current and future prospects. -
PWF Wilson - Current Opinion in Cardiology, 1999 - co-cardiology.com
... as lipids, glycemia, and hematologic markers, hold great promise ... tests and may provide
clues for interventions ... Coronary heart disease risk now can be estimated ...

F ROM THE S ARCOMERE TO THE N UCLEUS: Role of Genetics and Signaling in Structural Heart Disease -
RL Nicol, N Frey, EN Olson - Annual Reviews in Genomics and Human Genetics, 2000 - Annual Reviews
... via ?-ARK inhibition may attenuate disease progression in ... Rescue of mouse models
of heart failure by ... This paradigm may hold true for other signaling systems ...

Source: Google Scholar
 
 

Gene Holds Clues to Heart Disease

 

 

WEDNESDAY, Aug. 30 (HealthDay News) -- Variations in a gene that acts as a "switch" to turn on other genes could boost the risk of heart disease, an international study finds.

Scientists said that further study of the gene, called GATA2, and the genes it controls may reveal a regulatory network driving who inherits coronary artery disease. The research could lead to the development of genetic tests for the disease.

"We hope that one day it will be possible to use these gene variations to predict who is susceptible to cardiovascular disease. This finding is the first step before we can develop such a test for use in patients," study author Jessica J. Connelly, a postdoctoral fellow at the Center for Human Genetics at Duke University Medical Center, said in a prepared statement.

Connelly's team analyzed DNA from 3,000 people with a familial history of coronary artery disease. The findings were published in the August issue of the journal Public Library of Science (PLoS) Genetics.

Coronary artery disease -- which occurs when the arteries supplying blood to the heart become narrowed or clogged with plaque -- is the most common form of heart disease in the Western world. It affects more than 13 million Americans and is one of leading causes of death in the United States.

People at high risk for coronary artery disease are instructed to avoid behaviors, such as smoking or consuming foods high in saturated fats, that promote heart disease.

More information

The U.S. National Heart, Lung, and Blood Institute has more about coronary artery disease.

 
 
 
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