Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California
blank

 

Recent News and Articles on the Keywords: hiv infection + new hiv + prezista  Related to the article below (Last Update: 7/1/2008)


dBTechno
New HIV/AIDS Report
HealthNews, CA -
Also, in order to improve the nation's ability to track new HIV infections, the CDC has established a new reporting system, which will be able to ...
HIV Rates Up Among Crucial Risk Groups Ontario Now
"Second-wave" HIV hits young black gays PlanetOut
'Troubling' Rise in HIV Among Young Gay Men: CDC U.S. News & World Report
Washington Post - CBS News
all 102 news articles »

CTV.ca
Officials Praise New Test for Drug-Resistant TB
New York Times, United States -
Dr. Raviglione and other officials urged use of the test everywhere, particularly in poor countries where HIV is also epidemic. HIV, the virus that causes ...
New drug-resistance test gives hope to TB fight Reuters
all 189 news articles »
Caprivi High in New HIV Cases
AllAfrica.com, Washington -
The Government is concerned after data from the recent national HIV testing day shockingly revealed there is still an escalation in new infections in ...
Zambia: Circumcision Cardinal Tool in Aids Fight
AllAfrica.com, Washington -
The UN agencies emphasise that male circumcision does not provide complete protection against HIV infection. It should never replace other known effective ...
Uganda: How Crucial Are Men in HIV/Aids Fight? AllAfrica.com
Uganda: 'Circumcision Does Not Increase Sexual Behaviour' AllAfrica.com
Uganda: HIV/Aids is Hindering Growth of the African Child AllAfrica.com
all 4 news articles »
Couples-based Intervention May Limit HIV Transmission in African ...
Media Newswire (press release), NY -
A shift to a couples-based intervention for married and cohabiting couples in urban Zambia and Rwanda could prevent up to 60 percent of new HIV infections ...

TopNews
Zinc Finger Proteins Put Personalized HIV Therapy Within Reach
Science Daily (press release) -
These rare individuals are immune to HIV infection and seemingly are not affected by the non-functional CCR5 protein. The zinc finger approach aims to mimic ...
Sangamo technology shows promise in treating HIV CNNMoney.com
Scientists tweak cell, hold out HIV hope Calcutta Telegraph
HIV 'locked out' of sabotaged cells New Scientist (subscription)
Earthtimes (press release) - Medgadget.com
all 48 news articles »  SGMO - TPO:1584
OAFLA to step up war against HIV/AIDS in Africa
Kenya Broadcasting Corporation, Kenya -
... the war against HIV/AIDS in their respective countries, adding that the activities of OAFLA have contributed significantly to reduction of new infection ...
Let My People Go, AIDS Profiteers
Washington Post, United States - Jun 29, 2008
The plan states that the HIV infection rate among married couples is 42 percent, twice as high as the rate among prostitutes. Our requests for the source of ...
Web may hold key to fighting new HIV wave
Minneapolis Star Tribune, MN - Jun 29, 2008
The website, in development at the University of Minnesota, is the newest strategy to slow a second wave of the HIV/AIDS epidemic rising among young gay and ...
AIDS Healthcare Foundation: Criticism Mounts As CDC Delays Stark ...
Medical News Today (press release), UK -
"Playing the clock is simply not the answer, and we are losing valuable time in the conversations and changes necessary to effectively address HIV infection ...
Source: Google News

… of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 … -
B Clotet, N Bellos, JM Molina, D Cooper, JC … - The Lancet, 2007 - Elsevier
... in incidence of herpes simplex infection between the ... the clinical need for a new
PI capable of ... of TMC114/ritonavir in treatment-experienced HIV patients: POWER ...

Efficacy and safety of TMC114/ritonavir in treatment-experienced HIV patients: 24-week results of … -
C Katlama, R Esposito, JM Gatell, JC Goffard, B … - AIDS, 2007 - aidsonline.com
... New antiretroviral drugs ... Treatment for adult HIV infection: 2006 recommendations
of the ... safety of TMC114/ritonavir in treatment-experienced HIV patients: POWER 2 ...

Antiretroviral treatment of HIV infection: Swedish recommendations 2007 -
F JOSEPHSON - Scandinavian Journal of Infectious Diseases, 2007 - informaworld.com
... jointly published recommendations for the treatment of HIV infection. ... the previous
treatment recommendations, 1 new drug for the treatment of HIV has been ...

HIV entry inhibitors -
JA Est?, A Telenti - The Lancet, 2007 - Elsevier
... Their development might offer new perspectives in the management and
prophylaxis of HIV-1 infection. Panel. Highlights. ...

… Types on the Pharmacokinetics of Darunavir (TMC114)/Ritonavir in HIV-Negative Healthy Volunteers -
V Sekar, D Kestens, S Spinosa-Guzman, M De Pauw, E … - The Journal of Clinical Pharmacology, 2007 - jcp.sagepub.com
... protease inhibitors ? pharmacokinetics ? darunavir ? Prezista ? food. ... TMC114) is
a new protease inhibitor ... for the treatment of HIV infection in treatment ...

Pharmacokinetic Interaction between Darunavir Boosted with Ritonavir and Omeprazole or Ranitidine in … -
VJ Sekar, E Lefebvre, E De Paepe, T De Marez, M De … - Antimicrobial Agents and Chemotherapy, 2007 - Am Soc Microbiol
... Darunavir (DRV; TMC114; Prezista) is a new protease inhibitor (PI ... approvals for the
treatment of human immunodeficiency virus (HIV) infection in treatment ...

The Effect of Lopinavir/Ritonavir on the Renal Clearance of Tenofovir in HIV-Infected Patients -
JJ Kiser, ML Carten, CL Aquilante, PL Anderson, P … - Clin Pharmacol Ther, 2008 - nature.com
... of its use in the management of HIV infection. ... zidovudine, and lamivudine therapy
in HIV-infected adults ... rate from serum creatinine: a new prediction equation. ...

Overview of boosted protease inhibitors in treatment-experienced HIV-infected patients -
M Youle - Journal of Antimicrobial Chemotherapy, 2007 - Br Soc Antimicrob Chemo
... Two new PIs?tipranavir and darunavir?have recently entered ... these trials, HBV or HCV
co-infection was present ... with HBV- and HCV-uninfected HIV patients, but ...

[CITATION] Pharmacokinetic interaction between TMC114/ritonavir and tenofovir disoproxil fumarate in healthy … -
RMW Hoetelmans, K Marien, M De Pauw, A Hill, M … - British Journal of Clinical Pharmacology, 2007 - Blackwell Synergy
... TMC114 (Prezista?) is a new protease inhibitor ... TMC114 is approved in the USA in
combination with ritonavir for the treatment of HIV infection in treatment ...

[PDF] Development of resistance in patients with virologic failure (VF) on darunavir/ritonavir (DRV/r) or …
S De Meyer, E De Paepe, T Vangeneugden, B Van … - 47th Interscience Conference on Antimicrobial Agents and …, 2007 - tibotec.com
... The new HIV-1 protease ... The emergence of resistance to highly active ARV therapy
(HAART) presents a significant challenge to managing HIV-1 infection. ...

Source: Google Scholar
 
 

HIV infection, Prezista, a new protease inhibitor for patients who do not respond to existing drugs, approved

 
 
The FDA ( Food and Drug Administration ) approved Prezista ( Darunavir ), a new drug for adults whose infection with the human immunodeficiency virus ( HIV ) has not responded to treatment with other antiretroviral drugs.

Prezista, a HIV protease inhibitor, is approved to be co-administered with a low-dose of Ritonavir and other active anti-HIV agents.
Ritonavir, a protease inhibitor approved in 1996, slows the breakdown of Prezista in the body thereby increasing the concentration of Prezista.

The accelerated approval is based on evidence from two randomized, controlled studies comparing the safety and effectiveness of a Darunavir -Ritonavir combination with other Ritonavir-boosted protease inhibitor combinations. Patients in both arms of these trials also used other anti-HIV agents ( nucleoside reverse transcriptase inhibitors ) with or without Enfuvirtide ( Fuzeon ), a fusion inhibitor that inhibits the virus from entering the cell.
In these studies, patients on a Darunavir-Ritonavir combination experienced higher rates of reduction of their HIV viral load than patients on other Ritonavir-boosted protease inhibitor combinations.
Seventy percent of treatment-experienced patients achieved a virologic response, improving the treatment outcome, with Darunavir -Ritonavir in combination therapy compared to 21 percent in control group at week 24.

The most common side effects reported by patients on the Darunavir -Ritonavir regimen included diarrhea, nausea, and headache. About seven percent of patients on this combination therapy experienced skin rashes ranging from mild to serious.

The risks and benefits of Darunavir have not been established for adults who have not been previously treated for HIV, or for children.

Prezista and Ritonavir need to be taken with food, and the combination therapy doesn’t have not to be used together with St. John's wort or various other drugs, including certain anticonvulsants, antihistamines, sedatives and a few of the protease inhibitors.

Source: FDA, 2006
 
 
 
Google
Web www.iconocast.com
 
 
 

 

Continue News With: News7 ; News8 ; News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services. Home

 © 2002-2006

Keywords::

Contact Iconocast

Home Page