Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California
blank

 

Recent News and Articles on the Keywords: insights into + mule cloning + cloning  Related to the article below (Last Update: 7/1/2008)

Cloud Computing, Virtualization, Grid Computing - Examining the IT ...
SYS-CON Media, NJ - Jun 10, 2008
Google trends is a nice too that gives insight into broad search patterns. We all know that the term ?Cloud Computing? is relatively new to the Technology ...
Source: Google News

Human cloning: can it be made safe? -
SM Rhind, JE Taylor, PA De Sousa, TJ King, M … - Nature Reviews Genetics, 2003 - nature.com
... of these mechanisms will offer insights into the importance ... A mule cloned from foetal
cells by nuclear transfer. ... the first report of successful cloning of the ...

[PDF] The Tao of Cloning -
D Minton - Hawaii Research Centre for Futures Studies, 1997 - soc.hawaii.edu
... and my ability, may produce interesting insights into some of ... a differentiated adult
cell back into an undifferentiated ... but somewhere in between (ie a mule). ...

Review of Enucleation Methods and Procedures Used in Animal Cloning: State of the Art -
GP Li, KL White, TD Bunch - Cloning & Stem Cells, 2004 - liebertonline.com
... Reprogramming nu- clei: insights from cloning, nuclear transfer ... ovine somatic cells
develop into lambs after ... Pig cloning by microinjection of fetal fibroblast ...

Rabbit somatic cell cloning: effects of donor cell type, histone acetylation status and chimeric … -
F Yang, R Hao, B Kessler, G Brem, E Wolf, V … - Reproduction, 2007 - Soc Reprod Fertility
... Further, we tried to improve cloning efficiency by chimeric complementation of ... did
not affect development to blastocyst, after transfer into recipients, RCC ...

[PDF] Cloning: A Policy Analysis -
GH Javitt, MPH JD, K Suthers, K Hudson - Washington, DC, USA: Genetics and Public Policy Center, 2005 - dnapolicy.org
... to yield new and fundamental insights into human development ... much more precise genetic
modifications into farm animals. ... cats, 67 cows, 130,197,210 and a mule. ...

Analysis of papaya BAC end sequences reveals first insights into the organization of a fruit tree … -
CWJ Lai, Q Yu, S Hou, RL Skelton, MR Jones, KLT … - Molecular Genetics and Genomics, 2006 - Springer
... These insights will play a critical role in selecting ... The poplar genome was fragmented
into arti- Wcial BACs of ... CACTA, En/Spm 387 426 Mutator (MULE) 9 Mariner ...

[CITATION] Nuclear Transfer for Cloning Animals
H AgResearch, N Zealand
-

Cloned Mule Races to Finish Line
C Holden - ScienceNOW, 2003 - sciencenow.sciencemag.org
... is a sibling of a world-champion racing mule named Taz ... The birth of Idaho Gem may
yield insights into "the basic ... Now, he says, cloning may become an option for ...

Nuclear reprogramming in mammalian somatic cell nuclear cloning -
H Tamada, N Kikyo - Cytogenet Genome Res, 2004 - content.karger.com
... of living nuclei from blastula cells into enucleated frogs ... Kikyo N, Wolffe AP:
Reprogramming nuclei: insights from cloning ... Meerdo LN, Pate BJ: A mule cloned from ...

[PDF] Human embryos, stem cells and cloning?developments in research and regulations since 2001
BP Ltd - lockhartreview.com.au
... the information included in the reviews or to reveal new insights into the potential
of ... as a broad overview of the status of human embryology, cloning and stem ...

Source: Google Scholar
 
 

Cloned mules offer insight into calcium

The successful cloning of three mules sheds light on calcium's role in cell signaling and could be important for understanding the progression of human disease, according to US researchers.
 
The researchers, to discuss the cloning project this week at the American Association for the Advancement of Science annual meeting, said increasing calcium levels in the fluid surrounding cloned equine embryos proved the key to equine cloning.

Dr Gordon Woods from University of Idaho-Utah State University began to focus on calcium after becoming interested in why horses appear to be more resistant to some forms of cancer. It is not unusual for light-coloured horses to develop melanomas or skin cancers that do not metastasise and the cancer mortality rate for horses is approximately 8 per cent compard to 24 per cent for humans, said Woods.

Blood samples from men and stallions heightened his interest in calcium. Tests showed intracellular calcium concentrations in horse red blood cells were 2.3 times less than in human red blood cells. Extracellular calcium concentrations were reversed, with 1.5 times greater calcium concentrations outside cells in equines than in humans.

The lower concentrations of calcium within horse cells supported a model proposed by Woods. He postulated the equine system was ‘slower' physiologically than the human system. The lower cancer rates in equines appeared to support that idea.

Woods connected that hypothesis to embryonic development. "There are electrifying similarities between cancer metastasis and embryo division," he commented.

The researcher and his team agreed to try stimulating embryonic development by increasing calcium concentrations in the surrounding medium. The results were immediate, Woods said, generating a seven-fold increase in the two-week pregnancy rate of transferred clone embryos.

Only two pregnancies lasted two weeks without manipulating calcium levels. Nineteen pregnancies lasted two weeks or more with calcium treatments. Of 21 pregnancies detected at two weeks, 11 lasted 30 days and five lasted 45 days. Three pregnancies lasted past 60 days, and all of them survived full term and resulted in normal births.

The work also provides insight into calcium's role in cell signaling. As some human diseases progress, calcium levels escalate.

"The connection between calcium and many forms of human disease is well documented," said Dr Woods.

Calcium functions as a universal intracellular messenger, controlling processes as diverse as gene transcription, muscle transcription and cell proliferation, he noted.

A breakdown in calcium regulation is implicated in diseases ranging from cancer to diabetes, heart disease and neurological disorders.
 
 
 
Google
Web www.iconocast.com
 
 
 

 

Continue News With: News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services. Home

 © 2002-2006

Keywords::

Contact Iconocast

Home Page