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Recent News and Articles on the Keywords: colorectal cancer + selenium intake + selenium  Related to the article below (Last Update: 5/12/2008)


Jamaica Gleaner
Colorectal cancer in men - The third-most common cancer
Jamaica Gleaner, Jamaica - Apr 23, 2008
A varied diet, high in dietary fibre, fruits and vegetables to ensure adequate intake of folates, calcium, vitamin D, selenium and other phytochemicals, ...
Source: Google News

Selenium from High Selenium Broccoli Protects Rats from Colon Cancer 1 -
JW Finley, CD Davis, Y Feng - Journal of Nutrition, 2000 - Am Soc Nutrition
... Yang J., Hill KE, Burk R. Dietary selenium intake controls rat plasma ... DD Gallaher
Cruciferous Vegetables Reduce Morphological Markers of Colon Cancer Risk in ...

Lessons from Basic Research in Selenium and Cancer Prevention -
C Ip - Journal of Nutrition, 1998 - Am Soc Nutrition
... g). After a total follow-up of 8271 person-years, selenium treatment did ... much lower
prevalence of developing and dying from lung, colon or prostate cancer. ...

Risk of cancer in relation to serum concentrations of selenium and vitamins A and E: matched case- … -
JT Salonen, R Salonen, R Lappetel?inen, PH … - British Medical Journal (Clinical research ed.), 1985 - pubmedcentral.nih.gov
... A, Wilkinson G. Diet in the epidemiology of cancer of the colon and rectum ... Nutr Cancer. ...
Biochemical function of selenium and its relation to vitamin E. Fed Proc ...

A Prospective Cohort Study on Toenail Selenium Levels and Risk of Gastrointestinal Cancer -
PA Brandt, RA Goldbohm, P van't Veer, P Bode, E … - jnci, 1993 - jnci.oxfordjournals.org
... of this prospective cohort study was to investigate the association between toenail
selenium levels and risks of stomach cancer and colorectal cancer. ...

A case-control study of toenail selenium and cancer of the breast, colon, and prostate. -
P Ghadirian, P Maisonneuve, C Perret, G Kennedy, P … - Cancer Detect Prev, 2000 - ncbi.nlm.nih.gov
... the possible role of dietary and supplementary selenium intake in the etiology of
cancer, we carried out a case-control study of breast, colon, and prostate ...

The Selenium and Vitamin E Cancer Prevention Trial -
EA Klein, SM Lippman, IM Thompson, PJ Goodman, D … - World Journal of Urology, 2003 - Springer
... activity and other factors for colorectal cancer: a prospective ... and A and risk of
lung cancer: the NHANES ... et al (1998) Study of prediagnostic selenium level in ...

… incidence of prostate cancer with selenium supplementation: results of a double-blind cancer … -
F Password - Br J Urol, 1998 - Blackwell Synergy
... Selenium is an essential nutrient with a recommended ... in the additional endpoints
of total cancer incidence and ... and the incidence of lung, colon, and prostate ...

ASSOCIATION BETWEEN SERUM SELENIUM AND THE RISK OF CANCER -
JT SALONEN, G ALFTHAN, JK HUTTUNEN, P PUSKA - American Journal of Epidemiology, 1984 - Oxford Univ Press
... intake. Cancer Res 1981;41:31-4. 24. Jacobs MM, Forst CF, Beams FA. Biochemical
and clinical effects of selenium on dimethylhy- drazine-induced colon cancer in ...

Prospective Study of Toenail Selenium Levels and Cancer Among Women -
M Garland, JS Morris, MJ Stampfer, GA Colditz, VL … - jnci, 1995 - jnci.oxfordjournals.org
... site, including uterine cancer, colorectal cancer, melanoma, ovarian ... status and breast
cancer risk, strongly suggest that higher selenium intake within the ...

The protective role of selenium on genetic damage and on cancer -
K El-Bayoumy - Mutation Research-Fundamental and Molecular Mechanisms of …, 2001 - Elsevier
... In a study of selenium intake and colorectal cancer, that adjusted for possible
confounders, the individuals in the lowest quartile of plasma selenium had four ...

Source: Google Scholar
 
 

Higher selenium intake may reduce colorectal cancer risk

Higher blood levels of the trace mineral selenium are associated with lower rates of colorectal neoplasia, finds a new study, suggesting that raising dietary intake of the mineral could protect against colorectal cancer.
 
Selenium has previously been associated with cancer protection, with several studies showing that it may help combat prostate cancer. However past research on selenium and colorectal cancer has yielded mixed results.

Researchers from the University of Arizona say however that these studies may have been too small to track the mineral's impact.

To gain better insight into the selenium's anti-cancer role, they pooled data from three completed clinical trials of colorectal adenoma: the Wheat Bran Fiber Trial, the Polyp Prevention Trial, and the Polyp Prevention Study, each with several hundred participants.

After adjustment for age, gender, smoking status and study site, each of the trials showed lower risk of adenoma recurrence in patients with the highest quartile of blood selenium level versus those in the lowest quartile, although only the Polyp Prevention Study was statistically significant.

Writing in the 17 November issue of the Journal of the National Cancer Institute (96:1645-1647), the authors explain that there are several possible mechanisms for this effect, including protection against DNA damage, induction of apoptosis, and increased immune system activity.

The Selenium and Vitamin E Cancer Prevention Trial (SELECT), looking at the impact of these nutrients on prostate cancer, may provide some new insight into the mechanisms of the mineral's anti-cancer activity.

 
 
 
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