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Recent News and Articles on the Keywords: b vitamins + b vitamin + dementia  Related to the article below (Last Update: 7/1/2008)

Good Cholesterol Linked to Good Memory, British Study Finds
Bloomberg -
Niacin, a type of B vitamin, is the most effective approach, though it can cause flushing that limits its use. Abbott Laboratories sells an extended release ...
Putting energy drinks to the test
Dallas Morning News, TX - Jun 3, 2008
FUZE Beverage says the PowerShot packs "hours of horsepower" in a 2-ounce bottle, with the same amount of caffeine, B-vitamins and amino acids that are ...
A gulp of common sense
Detroit Free Press, United States - Jun 8, 2008
Some of the latest additions to this $3-billion business rely on healthy-sounding ingredients such as vitamin B and ginseng for that extra boost. ...
B12 pumps up energy drinks
Food Processing, IL - Jun 5, 2008
Some people diagnosed with dementia or Alzheimer's disease actually are suffering from the more reversible vitamin B12 deficiency, according to a Harvard ...
A Shopper's Guide To Memory
Evening Bulletin, PA - Jun 27, 2008
Other authorities list additional causes of dementia. For example, The American Medical Association Family Medical Guide (4th ed.) also lists vitamin B ...
A Multi-Pronged Approach to Brain Health
Huffington Post, NY - Jun 28, 2008
There are medications that lower the level of important brain nutrients in the body such as B vitamins and coenzyme Q10. Check with your doctor to screen ...
Host of Health Benefits Attributed to Sunlight
U.S. News & World Report, DC - Jun 25, 2008
Much attention has been paid to the benefits of vitamin D, which is manufactured when the sun's UV-B rays hit the skin and which protects against cancer, ...
5 Ways to Avoid Prescription Drugs
Stop Aging Now, DC - Jun 13, 2008
Take a high antioxidant multi-vitamin. It?s the only guaranteed way to get the amounts of vitamins E, D, and C, some of the B vitamins, and selenium which ...
Do your heart some good with vitamin D
Chicago Daily Herald, IL - Jun 15, 2008
Often, a simple blood test for vitamin D can determine whether you need additional supplementation. Patrick B. Massey, MD, Ph.D., is medical director for ...
Men, start taking preventative measures now
Nashua Telegraph, NH - Jun 10, 2008
Nutrients: B-vitamins for stress, zinc and soluble fiber. Oatmeal helps to reduce cholesterol levels, especially the steel-cut variety. ...
Source: Google News

… 5, 10-Methylene Tetrahydrofolate Reductase Gene in Patients with Alzheimer's Dementia A Case-Control … -
… , G Gallotta, G Guiotto, G Di Minno, B Vitamin - Logo, 2001 - content.karger.com
... not associated with an increased risk of either AD or vascular dementia [17 ... tHcy
levels in the MTHFR homozy- gotes, we found similar plasma folate and vitamin B ...

Vitamin B12 and folate in relation to the development of Alzheimer's disease -
… , H Basun, J Fastbom, B Winblad, L Fratiglioni - Neurology, 2001 - AAN Enterprises
... Folic acid, ageing, depression, and dementia BMJ, June 22 ... page, Neurology Home page
A. McCaddon, B. Regland, P ... and G. Davies Functional vitamin B12 deficiency and ...

B vitamins, homocysteine, and neurocognitive function in the elderly1 -
J Selhub, LC Bagley, J Miller, IH Rosenberg - American Journal of Clinical Nutrition, 2000 - Am Soc Nutrition
... decline ? dementia ? folate ? folic acid ? vitamin B-12 ? vitamin B-6 ?
homocysteine ? hyperhomocysteinemia ? brain ? B vitamins ? elderly ...

Hyperhomocysteinemia in dementia -
… E Artner-Dworzak, K Vrecko, B Widner, G Reibnegger … - Journal of Neural Transmission, 2000 - Springer
... Ueland PM (1998) Folate, vitamin B12, and serum ... JA (1999) Normohomocysteinaemia and
vitamin-treated hyperhomocysteinaemia ... CG, Lehmann W, Regland B (1998) Early ...

Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor -
SA Lipton, WK Kim, YB Choi, S Kumar, DM D'Emilia, … - Proceedings of the National Academy of Sciences, 1997 - National Acad Sciences
... Folate, and Vitamins B6 and B12 Blood Levels ... Spiro III High homocysteine and low
B vitamins predict cognitive ... folate as risk factors for dementia and Alzheimer ...

… Acid, and Transcobalamins in the Study of Vitamin B 12 Deficiency in Primary Degenerative Dementia -
… Regland, L Abrahamsson, CG Gottfries, E Magnus, B … - Logo, 1990 - content.karger.com
... B 12 analogues, homocysteine, MMA, and transcobalamins may be useful as markers
in studies aimed at clarifying the role of vitamin B12 deficiency in dementia ...

Homocysteine, vitamin B6, and vascular disease in AD patients -
JW Miller, R Green, DM Mungas, BR Reed, WJ Jagust - Neurology, 2002 - AAN Enterprises
... impairment, Alzheimer disease, and vascular dementia Am ... Home page, Neurology Home
page B. Borroni, C ... BR Reed, and WJ Jagust Homocysteine, vitamin B6, and vascular ...

[CITATION] … after cobalamin/folate supplementation in elderly patients with dementia and elevated plasma … -
K Nilsson, L Gustafson, B Hultberg? - International Journal of Geriatric Psychiatry, 2001
... Nutr Rev 54: 382?390. Brattstrom L, Israelsson B, Jeppsson JO, Hultberg
B. 1988. ... 1995. Vitamin B12 de?ciency and dementia. ...

Practice parameter: Diagnosis of dementia (an evidence-based review) Report of the Quality Standards … -
… -Bloom, N Relkin, GW Small, B Miller, JC Stevens - Neurology, 2001 - AAN Enterprises
... performance than nondeficient subjects, 120 but low vitamin B 12 levels in nondemented
subjects carried no risk for the subsequent development of dementia. ...

… Reductase Genotype, and Risk for Stroke, Vascular Dementia, and Alzheimer Disease in Northern … -
SP McIlroy, KB Dynan, JT Lawson, CC Patterson, AP … - Stroke, 2002 - Am Heart Assoc
... 728.[Abstract]; Guigoz Y, Vellas B, Garry PJ. ... Folate, vitamin B12, and serum total
homocysteine levels in ... of Alzheimer?s disease and vascular dementia: a case ...

Source: Google Scholar
 
 

Antioxidant, B vitamin combo to slow dementia?

Combining B vitamins with a powerful antioxidant could lower blood levels of the amino acid homocysteine enough to prevent dementia, claims a UK research firm preparing to test the theory in clinical trials.
 
High blood levels of homocysteine are a known risk factor for stroke and dementia but although homocysteine can be lowered by standard B vitamin supplements it is not yet known whether these can be used to treat or prevent dementia.

So far, the small studies on this effect have been disappointing.

However homocysteine research company Cobalz says that clinical trials starting in January could confirm that adding B vitamins to the powerful antioxidant N-acetylcysteine is superior to standard B vitamins in slowing the rate of cognitive decline in Alzheimer's disease patients.

Dementia already affects millions around the world and the threat is increasing with the growing numbers of elderly. Alzheimer's disease, the leading cause of dementia in the elderly, afflicts an estimated 4.5 million people in the US alone.

The condition is not only associated with homocysteine levels but also with ‘free radicals' that oxidise and damage an enzyme that breaks down homocysteine.

Cobalz has found that adding a powerful antioxidant to B vitamins lowers homocysteine levels even further and results in prompt, striking and sustained clinical improvement in patients.

Cobalz claims that the glutathione precursor N-acetylcysteine (NAC)is not only a potent antioxidant but also a source of cysteine. Cysteine is required to generate hydrogen sulphide - an important neuromodulator and vasorelaxant. Levels of hydrogen sulphide levels are severely decreased in the brains of Alzheimer's disease patients.

Last week the firm signed a licensing agreement with US pharmaceutical firm Pamlab to produce the product scheduled for use in the trial by researchers at the University of Texas Southwestern Medical Center.

Neil McCaddon, global head of licensing and corporate development at Cobalz, said: “We are very excited about the possibilities, and hope to announce some real breakthroughs for sufferers of dementia, and their carers.”

The UK company is seeking other licensing and development partners for the rest of the global market.

 
 
 
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