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Recent News and Articles on the Keywords: resveratrol has + healthy heart + resveratrol  Related to the article below (Last Update: 7/1/2008)

Healthy Returns ? How to Live Longer
Barron's - Jun 22, 2008
But scientists have found that a chemical called resveratrol, famously present in red wine, may mimic the effects of caloric restriction. ...

MSN India
Red Wine, Healthy Heart: It?s All in the Genes
MedHeadlines, IL - Jun 5, 2008
The research team reports that resveratrol, even in low doses, seems to mimic the heart-healthy effect of the restricted diet by effectively preventing ...
Resveratrol to stop aging? Los Angeles Times
Red Wine Proves To Be Very Heart Healthy RedOrbit
Red wine stops effects of high-fat diet Telegraph.co.uk
The Press Association - University of Florida
all 104 news articles »
Red wine component resveratrol might fight obesity, lab tests show
Science News - Jun 16, 2008
What?s more, in these tests resveratrol also induced mature fat cells to maintain healthy amounts of a valuable compound called adiponectin, which earlier ...
Red Wine's Resveratrol May Help Battle Obesity Science Daily (press release)
all 20 news articles »

CBS News
Red Wine A Weapon In Battle Of The Bulge
CBS News, NY - Jun 18, 2008
An antioxidant found in red wine and grapes known as resveratrol, already thought to help keep the heart healthy and to ward off cancer, may also turn out ...

HealthNews
The French Way to a Healthy Heart: Red Wine?
HealthNews, CA - Jun 10, 2008
Scientists now think that it may be because of something called resveratrol in their diet. Certainly not a common household word, resveratrol is a natural ...
Now, red wine to fight obesity
Times of India, India - Jun 18, 2008
"Resveratrol has anti-obesity properties by exerting its effects directly on the fat cells. Thus, resveratrol might help to prevent development of obesity ...

NHS Choices
Heart health and red wine
NHS Choices, UK - Jun 4, 2008
It is known that restricting calorie intake slows down several aspects of ageing and has beneficial effects in mammals. Resveratrol has been shown to extend ...

Food Consumer
Grapes' resveratrol may help prevent obesity
Food Consumer, IL - Jun 16, 2008
Early research has found resveratrol protected laboratory mice fed a high fat diet from having health problem associated with obesity by mimicking the ...
ALL ABOUT FOOD: We?re on the food science merry-go-round
Coastline Pilot, CA - Jun 27, 2008
Considering that there are many other resveratrol-like compounds in red wine and that mice have a higher metabolic rate, a mere four, five-ounce glasses ...
Uncorked: Revitalizing the body with resveratrol?
Anniston Star (subscription), AL - Jun 17, 2008
In the past few weeks all major news outlets have been reporting the results of several studies that indicate resveratrol given to laboratory mice in high ...
Source: Google News

The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and … -
CR Pace-Asciak, S Hahn, EP Diamandis, G Soleas, DM … - Clinica Chimica Acta, 1995 - Elsevier
... 3. Preparation of plasma and platelets Healthy volunteers who ... synthesis of 12-HETE
which has been postulated ... Finally, trans-resveratrol blocks the synthesis of ...

Chemopreventive Agent Resveratrol, a Natural Product Derived From Grapes, Triggers CD95 Signaling- … -
MV Clement, JL Hirpara, SH Chawdhury, S Pervaiz - Blood, 1998 - bloodjournal.hematologylibrary.org
... the reduced risk of coronary heart disease associated ... obtained from blood donated
by healthy volunteers by ... Our data show that resveratrol has minimal toxicity ...

Resveratrol, a Polyphenolic Compound Found in Wine, Inhibits Tissue Factor Expression in Vascular … -
UR Pendurthi, JT Williams, LVM Rao - Arteriosclerosis, Thrombosis, and Vascular Biology, 1999 - Am Heart Assoc
... activity of synthetic and natural resveratrol in red ... as modulators of platelet
aggregation in healthy human subjects ... tissue factor pathway: how it has become a ...

Biological effects of resveratrol -
L Fr?mont - Life Sciences, 2000 - Elsevier
... test the effects of polyphenols in 24 healthy male subjects ... The activity of resveratrol
3-0-PD-glucopyranoside on platelet aggregation has also been reported ...

Resveratrol Has No Effect on Lipoprotein Profile and Does Not Prevent Peroxidation of Serum Lipids … -
JF Turrens, J Lariccia, MG Nair - Free Radical Research, 1997 - informaworld.com
... was orders of magnitude higher than the amounts found in wine, these results suggest
that if resveratrol has any effect against coronary heart diseases, it is ...

Is Resveratrol an Estrogen Agonist in Growing Rats? 1 -
RT Turner, GL Evans, M Zhang, A Maran, JD Sibonga - Endocrinology, 1999 - Endocrine Soc
... General The animals appeared healthy. ... to be bioavailable to several tissues, including
heart, liver, and ... However, resveratrol has been shown to be absorbed by ...

Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin … -
J Martinez, JJ Moreno - Biochemical Pharmacology, 2000 - Elsevier
... 4). DISCUSSION Resveratrol has been reported to protect against atheroscle-
rosis [2] and coronary degenerative disease(s) [14]. The ...

Effect of Enological Practices on the Resveratrol Isomer Content of Wine -
P Jeandet, R Bessis, BF Maume, P Meunier, D Peyron … - Journal of Agricultural and Food Chemistry, 1995 - pubs.acs.org
... grapes than in those vinted from healthy and moderately ... Finally, this study has clearly
established the presence ... of resveratrol in wine, a form only slightly ...

Molecular mechanism of the chemopreventive effect of resveratrol -
Z Dong - Mutation Research-Fundamental and Molecular Mechanisms of …, 2003 - Elsevier
... An accumulation of evidence has further shown that ... Levels of cis- and trans-resveratrol
and their ... modulators of platelet aggregation in healthy human subjects. ...

… 12-Dimethylbenz (a) anthracene-induced Mammary Carcinogenesis in Rats by Resveratrol Role of Nuclear … -
S Banerjee, C Bueso-Ramos, BB Aggarwal - Cancer Research, 2002 - AACR
... Resveratrol (3,4'-trihydroxystilbene), a natural phytoalexin present ... and many other
natural sources, has been suggested ... the risk of coronary heart disease and ...

Source: Google Scholar
 
 

Resveratrol has multiple action on heart health

Resveratrol, the antioxidant found in red wine, may help protect heart health by limiting the effects of cardiac fibrosis, a hardening of the heart tissue, finds new animal research.
 
The findings add to other ways in which resveratrol is known to benefit heart health -helping to prevent blood clots and also possibly reducing cholesterol.

Resveratrol remains a new ingredient to the supplement industry and is not currently supplied by European grape products companies. There are some resveratrol supplements available in the US although European industry remains wary over its regulatory status.

Nevertheless research showing that this ingredient has a major impact on heart health could see increasing interest in its use as a supplement.

Writing in the American Journal of Physiology – Heart and Circulatory Physiology, Joshua Bomser and colleagues from Ohio State University report that treating rat heart cells called fibroblasts with resveratrol prevented the actions of a potent hormone called angiotensin II.

In hypertension and heart failure, angiotensin II is produced at a high level, which is the body's way of trying to repair damage to the heart and to increase blood pressure.

But the hormone often causes cardiac fibroblast production to go into overdrive, and, as a result, these cells produce excessive amounts of collagen – a fibrous substance found in bone, tendons, ligaments and other connective tissues.

"This hyper-secretion of collagen leads to a stiffening of the heart muscle," Bomser said. "So the heart has to work harder to pump blood, which causes further damage to the myocardium."

The researchers pretreated rat cardiac fibroblasts with resveratrol prior to adding angiotensin II to the cells. Resveratrol treatment inhibited angiotensin II's ability to cause growth and proliferation of the cardiac fibroblasts.

Resveratrol also prevented these cells from turning, or differentiating, into myofibroblasts, a specialized type of fibroblast that produces large quantities of collagen.

"These results suggest that resveratrol has anti-fibrotic properties in the myocardium," Bomser said.

 
 
 
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