Lowering cholesterol concentrations and mortality: a quantitative review of primary prevention … -
MF Muldoon, SB Manuck, KA Matthews - BMJ: British Medical Journal, 1990 - pubmedcentral.nih.gov
... Lancet. 1971 Mar 6;1(7697):464?467. [PubMed]; Oliver MF. Reducing cholesterol does
not reduce mortality. J Am Coll Cardiol. 1988 Sep;12(3):814?817. ...

[PDF] Statins do more than just lower cholesterol -
CJ Vaughan, MB Murphy, BM Buckley - coronary artery disease - westhertshospitals.nhs.uk
... Inhibition of endogenous cholesterol synthesis by macrophages has the potential
to reduce macrophage activation, foam-cell formation, and the thrombogenicity ...
-

… of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels Results of … -
JR Downs, M Clearfield, S Weis, E Whitney, DR … - JAMA, 1998 - Am Med Assoc
... Context.? Although cholesterol-reducing treatment has been shown to reduce fatal
and nonfatal coronary disease in patients with coronary heart disease (CHD ...

… of pravastatin on coronary events after myocardial infarction in patients with average cholesterol … -
FM Sacks, MA Pfeffer, LA Moye, JL Rouleau, JD … - N Engl J Med, 1996 - Mass Med Soc
... events for patients with a baseline LDL cholesterol level lower than 125 mg/dl ... Comment:
This important study demonstrates that reducing average levels of ...

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 … -
… , R Peto, R Collins, R Simes, CTT Cholesterol … - Lancet, 2005 - ncbi.nlm.nih.gov
... Results of previous randomised trials have shown that interventions that lower LDL
cholesterol concentrations can significantly reduce the incidence of ...

Implications of recent clinical trials for the National Cholesterol Education Program Adult … -
SM Grundy, JI Cleeman, CN Bairey Merz, HB Brewer, … - Journal of the American College of Cardiology, 2004 - Am Coll Cardio Found
... Until recently, however, cholesterol-lowering clinical trials in ... in epidemiological
studies in the lower ranges of ... of benefit from further reducing already low ...

Dietary Isoflavones Reduce Plasma Cholesterol and Atherosclerosis in C57BL/6 Mice but not LDL … -
EA Kirk, P Sutherland, SA Wang, A Chait, RC … - Journal of Nutrition, 1998 - Am Soc Nutrition
... Soy protein-based diets lower plasma cholesterol levels in ... 1993 and 1996) that could
protect against atherosclerosis by reducing LDL oxidation, believed ...

Communicating the risk reduction achieved by cholesterol reducing drugs -
JA Skolbekken - BMJ, 1998 - pubmedcentral.nih.gov
... Reducing the risk of coronary events: evidence from the Scandinavian simvastatin
survival study (4S) Am J Cardiol 1995. ... Lower patients? cholesterol now. ...

By how much and how quickly does reduction in serum cholesterol concentration lower risk of … -
MR Law, NJ Wald, SG Thompson - BMJ, 1994 - Mass Med Soc
... Comment: The numbers may vary, but the consensus of these studies is that a modest
reduction in serum cholesterol can significantly reduce the risk for ...

… Biology for the Investigation of the Treatment Effects of Reducing Cholesterol A Randomized Trial … -
AJ Taylor, SM Kent, PJ Flaherty, LC Coyle, TT … - Circulation, 2002 - Am Heart Assoc
... ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing
Cholesterol. ... to levels well below 100 mg/dL would further reduce the burden ...