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Recent News and Articles on the Keywords: insulin resistance + premature aging + insulin  Related to the article below (Last Update: 7/8/2008)


Canada.com
Liver Protein Associated With Type 2 Diabetes In Older Adults
Science Daily (press release) -
Type 2 diabetes is a metabolic disorder characterized by insulin resistance that has become a global epidemic. The increased prevalence of obesity is a ...
A Blood Marker Could Spot Diabetes Risk U.S. News & World Report
Liver Protein Linked to Diabetes Risk in Older Adults MedPage Today
Elevated level of certain protein associated with increased risk ... EurekAlert (press release)
all 27 news articles »

Fresh News
Overweight, Insulin Resistant Women At Greater Risk Of Advanced ...
Science Daily (press release) - Jul 7, 2008
The study found that women who were overweight or had signs of insulin resistance -- such as elevated blood glucose or insulin levels -- were about 50 per ...
Overweight linked to breast cancer in postmenopausal women Food Consumer
Overweight women risk diabetes and cancer Melbourne Herald Sun
Advanced breast cancer more likely in older women at risk of ... News-Medical.net
all 34 news articles »
Trans-fatty Acids Do Not Appear To Increase The Risk Of Diabetes
Science Daily (press release) -
... but a new dietary study in rats suggests that trans-fats do not increase the risk of insulin resistance and diabetes, which may ease at least one area ...
Resistance training can help diabetics
The Coloradoan, CO - Jul 7, 2008
With diabetes, the pancreas does not produce enough insulin, or insulin is unable to transport the glucose to the cells (insulin resistance). ...
Health news of note
The Grand Rapids Press - MLive.com, MI -
Insulin resistance, a risk factor for diabetes and heart disease usually seen in obese people, is common among lean black women. A Wake Forest University ...
Liver Protein Linked to Diabetes Risk
WebMD - 28 minutes ago
Scientists have previously linked high levels of the protein, called fetuin-A, with insulin resistance, but the protein's role in the development of ...
Study links diabetes, advanced breast cancer
ABC Online, Australia - Jul 7, 2008
"We found that women who were overweight or with insulin resistance were more likely to be diagnosed with an advanced stage of breast cancer," she said. ...
Single Mechanism For Hypertension, Insulin Resistance And Immune ...
Science Daily (press release) - Jun 30, 2008
"The elegant study by Delano and Schmid-Sch?nbein points to a potentially very important overlap of an insulin resistance mechanism with hypertension in the ...
Insulin Resistance Linked To Peripheral Artery Disease
eMaxHealth.com, NC - Jul 4, 2008
Researchers at Brigham and Women?s Hospital (BWH) have shown for the first time that a strong association exists between insulin resistance and peripheral ...
Insulin Resistance Tied to Peripheral Artery Disease
Washington Post, United States - Jun 16, 2008
MONDAY, June 16 (HealthDay News) -- A new study has found a strong association between insulin resistance and peripheral arterial disease (PAD), ...
Source: Google News

… and lipid metabolism in veterans with paraplegia or quadriplegia: a model of premature aging. -
WA Bauman, AM Spungen - Metabolism, 1994 - ncbi.nlm.nih.gov
... in veterans with paraplegia or quadriplegia: a model of premature aging. ... compared
with controls, suggesting an accentuated state of insulin resistance in those ...

Effects of glucose/insulin perturbations on aging and chronic disorders of aging: the evidence -
HG Preuss - Journal of the American College of Nutrition, 1997 - Am Coll Nutrition
... to age-induced insulin resistance can react ... perturbations in glucose/insulin metabolism
are ... in diabetes mellitus, commonly associated with "premature aging". ...

Insulin Resistance and Cardiovascular Disease 1 -
SI McFarlane, M Banerji, JR Sowers - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc
... hypercoagulability, endothelial dysfunction, albuminuria, and premature CVD ... role
of uric acid in the obesity-insulin resistance syndrome ... The Normative Aging Study ...

Insulin Resistance with Aging: Effects of Diet and Exercise. -
AS Ryan - Sports Medicine, 2000 - sportsmedicine.adisonline.com
... insulin-like growth factor-I, adiposity and aging. ... signaling and the molecular
mechanisms of insulin resistance. ... Evidence against either a premature stop codon ...

Suppression of Aging in Mice by the Hormone Klotho -
H Kurosu, M Yamamoto, JD Clark, JV Pastor, A Nandi … - Science, 2005 - sciencemag.org
... KL -/- mice suffered premature death around two months ... Because Klotho must mediate
aging through effects of ... were unable to detect insulin resistance in female ...

… Diastolic Filling and Accumulation of Myocardial Collagen at Insulin-Resistant Prediabetic Stage of … -
K Mizushige, L Yao, T Noma, H Kiyomoto, Y Yu, N … - Circulation, 2000 - Am Heart Assoc
... our subjects were in the stage of prediabetes and insulin resistance at 10 ... Cardiac
fibrosis and collagen deposition may be related to premature aging and the ...

Insulin Resistance as a Predictor of Age-Related Diseases -
FS Facchini, N Hua, F Abbasi, GM Reaven - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc
... Like Growth Factor System in Mammalian Aging Endocrinology, September 1 ... EM Robinson,
and WS Cutfield Premature Birth and Later Insulin Resistance N. Engl. ...

Minireview: Role of the Growth Hormone/Insulin-Like Growth Factor System in Mammalian Aging -
A Bartke - Endocrinology, 2005 - Endocrine Soc
... of growth hormone (GH) overexpression and GH resistance. ... levels of thyroid hormones,
insulin, and glucose ... expression in delayed and premature aging mouse models ...

[PDF] Insulin-like growth factors and neoplasia -
MN Pollak, ES Schernhammer, SE Hankinson - Nature Reviews Cancer, 2004 - upload.mcgill.ca
... proliferation and prolongs survival of cells propagated in tissue culture 4 .By
con- trast, ageing at the ... The syndrome of insulin resistance,characterized by ...
-

Adverse effects of psychosocial stress on gonadal function and insulin levels in middle-aged males. -
PM Nilsson, L Moller, K Solstad - J Intern Med, 1995 - ncbi.nlm.nih.gov
... with a process of premature ageing in middle-aged males, corresponding to a hypogonadal
state as well as to indirect signs of increased insulin resistance. ...

Source: Google Scholar
 
 

Insulin resistance, weight gain linked to premature aging

 

 
Tulane University researchers demonstrated that people with insulin resistance and weight gain also have prematurely shortened white blood cell telomeres - a widely recognized sign of aging.

Telomeres are part of each chromosome and naturally become shorter over time as cells multiply and reproduce.

“ We know that obesity and insulin resistance place a physical burden on the body, leading to inflammation, the production of more blood to feed the body, and oxidative stress, all of which are important factors in the biology of aging,” says cardiologist Gerald Berenson, co-author of the study.

Researchers analyzed blood drawn from 49 adults who participated in the Bogalusa Heart Study at least twice between 1988 and 2001.
They also analyzed data related to weight, blood pressure and diet and lifestyle factors.

The researchers found that as people's weight and insulin resistance increased, they also experienced a shortening of the telomeres of their white blood cells.

Insulin resistance is a reduced sensitivity in the tissues of the body to the action of insulin, a hormone that brings glucose to those tissues to be used as a source of energy. To compensate, the body works harder to produce more insulin while at the same time failing to lower blood sugar levels.

The Bogalusa Heart Study is the longest-running, biracial, community-based study of heart disease risk factors beginning in childhood in the world.

Since its inception in 1973, Berenson and colleagues have screened over 16,000 adults and children in the Bogalusa, Louisiana area in an effort to understand heart disease risk factors over the lifespan.
Children who began the study in the 1970s while they were in elementary school are now adults who continue to participate in the screening process.

The study has been published in Circulation.

Source: Tulane University, 2005
 
 
 
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