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Recent News and Articles on the Keywords: menstrual cycle + cycle + seizures  Related to the article below (Last Update: 8/5/2008)

Critics question use of antidepressants to treat PMS
Canada.com, Canada -
Some women are already taking antidepressants continuously for severe PMS, or for part of their menstrual cycle - from ovulation to menstruation. ...
Critics question use of antidepressants to treat PMS
Times Colonist, Canada - 4 minutes ago
Some women are already taking antidepressants continuously for severe PMS, or for part of their menstrual cycle from ovulation to menstruation. ...
Meta-analysis: SSRIs in the Treatment of PMS and PMDD
Medscape (subscription) -
Many women experience certain recurring symptoms during the menstrual cycle. In the majority of cases, these symptoms occur just prior to menstruation. ...

BBC Birmingham
Oestrogen - a beneficial addition to treatment of schizophrenia in ...
News-Medical.net, Australia -
They say it may also be useful during low-oestrogen phases of a woman's menstrual cycle. The researchers say that the hormone might have a rapid effect on ...
Hormone eases psychotic symptoms BBC News
Estrogen may ease schizophrenia in women-study Reuters
all 32 news articles »

Canada.com
New fertility technique targets women with cancer
Reuters UK, UK - Jul 7, 2008
But if a cancer diagnosis comes at the start of the menstrual cycle, many women are unable to delay chemotherapy and preserve their eggs, Michael Von Wolf ...
New Technique Helps Preserve Fertility In Cancer Patients RedOrbit
New way to help women hit by cancer treatment have babies Telegraph.co.uk
Cancer patients' fertility hope BBC News
Cancer Research UK - News & Resources - Daily Mail
all 23 news articles »
New Ovarian Stimulation Technique Offers More Cancer Patients The ...
Science Daily (press release) - Jul 7, 2008
However, conventional protocols involve starting ovarian stimulation only at the beginning of a woman's menstrual cycle (the day that menstruation starts). ...
Is she cheating? And the value of supplements
Jamaica Observer, Jamaica - Jul 6, 2008
The normal menstrual cycle is usually every 21 to 35 days with an average of 28 days. The menstrual cycle might change due to several factors. ...
Interest Of Extended-Cycle Oral Contraceptive Increasing Among ...
Medical News Today (press release), UK - Jul 30, 2008
More than two-thirds of women in the US said they are interested in suppressing monthly bleeding using extended-cycle oral contraceptives, according to a ...
The Sex Cycle
CBS 4, FL - Jul 29, 2008
In the earliest part of the menstrual cycle, known as the follicular phase, lower levels of progesterone make it more difficult to quit smoking. ...
Self-administered breast exams never a bad idea
Fort Worth Business Press, TX -
... whether it?s the first day of every month, the first Sunday of every month, the first Sunday after each menstrual cycle or whatever is easy to remember. ...
Source: Google News

Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle. -
T Backstrom - Acta Neurol Scand, 1976 - ncbi.nlm.nih.gov
Acta Neurol Scand. 1976 Oct;54(4):321-47. Epileptic seizures in women related
to plasma estrogen and progesterone during the menstrual cycle. ...

Ovarian hormones, anticonvulsant drugs, and seizures during the menstrual cycle in women with … -
D Rosciszewska, B Buntner, I Guz, L Zawisza - British Medical Journal, 1986 - jnnp.bmj.com
... PAPERS. Ovarian hormones, anticonvulsant drugs, and seizures during the menstrual
cycle in women with epilepsy. D Rosciszewska, B Buntner, I Guz and L Zawisza. ...

Menstrual cycle and ovary alterations in women with epilepsy on antiepileptic therapy. -
G Murialdo, CA Galimberti, F Magri, P Sampaolo, F … - J Endocrinol Invest, 1997 - ncbi.nlm.nih.gov
J Endocrinol Invest. 1997 Oct;20(9):519-26. Menstrual cycle and ovary
alterations in women with epilepsy on antiepileptic therapy. ...

Menstrual cycle effects on cortical excitability -
MJ Smith, JC Keel, BD Greenberg, LF Adams, PJ … - Neurology, 1999 - AAN Enterprises
... menstrual cycle. J Clin Endocrinol Metab 1973;36:475?481.[Medline]; Thomas J, McLean
JH. Castration alters susceptibility of male rats to specific seizures. ...

[CITATION] Physiological Changes During the Menstrual Cycle and Their Effects on the Pharmacokinetics and … -
ADM Kashuba, AN Nafziger - Clinical Pharmacokinetics, 1998
... 210 3.2 Epilepsy . . . . . 210 4. Menstrual Cycle Influences on Drug ...

… , Progesterone, and Ionized Calcium on Seizures During the Menstrual Cycle of Epileptic Women -
JJ Jacono, JMD Robertson - Epilepsia, 1987 - Blackwell Synergy
... unreported. Key Words: Epilepsy- Seizures- Menstrual cycle- Hormones-
Estrogen-Progesterone-Calcium-Hypothalamo- hypophyseal system. The ...

Analysis of seizure dispersion during menstrual cycle in women with epilepsy.
D Rosciszewska - Monogr Neural Sci, 1980 - ncbi.nlm.nih.gov
... Rosciszewska D. The correlation between seizures and menstrual cycle was
studied in 69 females with epilepsy, mean age 28.7 years. ...

Effects of the Menstrual Cycle on Medical Disorders -
AM Case, RL Reid - Archives of Internal Medicine, 1998 - Am Med Assoc
... seizure activity. 47 Frequency of seizure has been shown to increase during
2 specific times in the menstrual cycle. The first corresponds ...

Ovarian cycle- linked changes in GABA A receptors mediating tonic inhibition alter seizure … -
JL Maguire, BM Stell, M Rafizadeh, I Mody - Nature Neuroscience, 2005 - nature.com
... human condition of catamenial epilepsy, in which 75% of epileptic women report seizure
exacerbation related to specific stages of their menstrual cycle 2 . The ...

The Effect of the Menstrual Cycle on Anterior Cruciate Ligament Injuries in Women as Determined by … -
EM Wojtys, LJ Huston, MD Boynton, KP Spindler, TN … - American Journal of Sports Medicine, 2002 - ajsm.highwire.org
... B, et al: Effects of ovarian steroid hormones on brain excitability and their relation
to epilepsy seizure variation during the menstrual cycle, in Porter RJ ...

Source: Google Scholar
 
 

Changes in brain receptors affect seizure and anxiety during the menstrual cycle

 
 
A study, carried out by researchers at University of California – Los Angeles ( UCLA ), showed that changes in certain brain receptors can affect seizures and anxiety during the menstrual cycle.
These findings could lead to novel therapies for premenstrual dysphoric disorder ( PMDD, formerly known as PMS ) and other central nervous system symptoms associated with the menstrual cycle.

The study, " Ovarian Cycle-Linked Changes in GABAA Receptors Mediating Tonic Inhibition Alter Seizure Susceptibility and Anxiety, " has been published in Nature Neuroscience.

The findings also may be applicable to post-partum depression and mood swings during pregnancy, and may explain how stress hormones affect the brain, said Istvan Mody, at the Reed Neurological Research Center at the David Geffen School of Medicine at UCLA.

" This may provide novel therapeutic targets for curing PMDD ( PMS ) or catamenial epilepsy, a form of epilepsy in women that is exacerbated during certain stages of the menstrual cycle, or other mental or neurological disorders related to changes in steroid hormone levels, " said Mody, the study's lead researcher. " If some of our findings are replicated in humans, our study would provide some testable predictions about new therapies. "

Basing their findings on a study of the estrous cycle in mice - the equivalent of the human menstrual cycle - the researchers found that a specific subclass of the receptors called GABAA receptors change in the hippocampus during the cycle.
These changes take place in a part of the brain where progesterone-derived neurosteroids are active, and are inexorably linked to an altered behavior of nerve cells, which in turn changes the whole animal's susceptibility to seizures and anxiety.

" This may be quite relevant to the way nerve cells respond to stimuli in the human brain during the menstrual cycle, " Mody said.

The changes may spark seizures in women with catamenial epilepsy and may lead to the increased anxiety women experience during PMDD.

The next step will be to determine the precise mechanisms behind these changes.

Source: University of California - Los Angeles ( UCLA ), 2005
 
 
 
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