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Recent News and Articles on the Keywords: undergone hysterectomy + postmenopausal women + estrogen  Related to the article below (Last Update: 5/12/2008)

Treatment Advances For Fibroids, Menopause
Science Daily (press release) - May 4, 2008
ScienceDaily (May 4, 2008) ? Women with fibroids and endometriosis facing the possibility of hysterectomy may now choose less invasive treatment options to ...
Hormones, the Brain, and Me
RedOrbit, TX - May 6, 2008
Recently, a transdermal T preparation (a T "patch") was developed to treat decreased sexual desire in postmenopausal women who were already taking estrogen. ...
Persistent Hot Flushes in Older Postmenopausal Women
Archives of Internal Medicine - Apr 28, 2008
Objective To examine the prevalence, natural history, and predictors of hot flushes in older postmenopausal women. Methods Prevalence, severity, and 3-year ...
Source: Google News

Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women -
S Hulley, D Grady, T Bush, C Furberg, D Herrington … - JAMA, 1998 - Am Med Assoc
... coronary disease who had not had a hysterectomy. Postmenopausal was defined as age
at least 55 years ... of estrogen plus progestin therapy in women classified by ...

Use of Hormone Replacement Therapy by Postmenopausal Women in the United States -
NL Keating, PD Cleary, AS Rossi, AM Zaslavsky, JZ … - Annals of Internal Medicine, 1999 - annals.highwire.org
... undergone natural menopause, women who had undergone hysterectomy were considered
postmenopausal whether or not they had undergone bilateral salpingo ...

… of Estrogen Plus Progestin on Breast Cancer and Mammography in Healthy Postmenopausal Women: The … -
RT Chlebowski, SL Hendrix, RD Langer, ML Stefanick … - Obstetrical & Gynecological Survey, 2003 - obgynsurvey.com
... Pap smears in 5682 women who had undergone hysterectomy (N Engl ... cologic examination
in a woman who has had a hysterectomy? ... Stroke in Postmenopausal Women: The ...

Alendronate and Estrogen Effects in Postmenopausal Women with Low Bone Mineral Density 1 -
HG Bone, SL Greenspan, C McKeever, N Bell, M … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc
... in women who had undergone hysterectomy, the results ... on bone mineral density in
post-menopausal women: a meta ... of Treatment of Postmenopausal Osteoporosis: A ...

Effect of Oestrogen During Menopause on Risk and Age at Onset of Alzheimer's Disease. -
MX Tang, D Jacobs, Y Stern, K Marder, P Schofield, … - Obstetrical & Gynecological Survey, 1997 - obgynsurvey.com
... proportion of women who had undergone hysterectomy than of ... lead to begin to assess
whether estrogen treatment of postmenopausal women might influence ...

Ten Years' Experience With Alendronate for Osteoporosis in Postmenopausal Women. -
HG Bone, D Hosking, JP Devogelaer, JR Tucci, RD … - Obstetrical & Gynecological Survey, 2004 - obgynsurvey.com
... with hysteroscopy, dilation and curettage, or hysterectomy (Fig ... 1). Fifty-five women
were postmenopausal and 21 ... with multiple births who had undergone IVF were ...

… : a Clinical Trial of Postmenopausal Women Randomly Assigned to Receive Raloxifene, Estrogen, or … -
M Freedman, JS Martin, JO'Gorman, S Eckert, ME … - jnci, 2001 - jnci.oxfordjournals.org
... on mammographic density of selective estrogen receptor modulators ... prevention trial,
healthy postmenopausal women who had undergone hysterectomy less than 15 ...

The risk of breast cancer in postmenopausal women who have used estrogen replacement therapy -
PA Wingo, PM Layde, NC Lee, G Rubin, HW Ory - JAMA, 1987 - Am Med Assoc
... All subjects in the analysis were postmenopausal women enrolled from eight geographic
areas. ... Among women who had undergone hysterectomy but who still had ...

Combined Estrogen and Progestin Hormone Replacement Therapy in Relation to Risk of Breast Cancer in … -
JL Stanford, NS Weiss, LF Voight, JR Daling, LA … - Obstetrical & Gynecological Survey, 1996 - obgynsurvey.com
... Postmenopausal hormone therapy of some known type ... progestin HRT who had undergone
hysterectomy with bilateral ... In women who experienced natural menopause, the ...

Myocardial Infarction and the Use of Estrogen and Estrogen-Progestogen in Postmenopausal Women -
S Sidney, DB Petitti, CP Quesenberry Jr - Annals of Internal Medicine, 1997 - annals.highwire.org
... Women who have undergone both hysterectomy and ... of long term estrogen support after
hysterectomy. ... associated with long-term postmenopausal estrogen therapy. ...

Source: Google Scholar
 
 

Postmenopausal women who have undergone hysterectomy should not take Estrogen

 

 
The U.S. Preventive Services Task Force issued a new recommendation against the routine use of Estrogen to prevent chronic conditions such as heart disease, stroke and osteoporosis in postmenopausal women who have undergone a hysterectomy.
This recommendation is based on recent evidence from the National Institutes of Health’s Women’s Health Initiative clinical trial and other studies.

In 2002, the Task Force found insufficient evidence to recommend for or against the routine use of Estrogen alone to prevent chronic conditions in women who have completed menopause and had a hysterectomy.

Now, after reviewing new findings from the Women’s Health Initiative, the Task Force noted that, although Estrogen can have positive effects such as reducing the risk for fractures, hormone therapy should not be used routinely because it appears to increase women’s risk for potentially life-threatening clots that block blood vessels ( venous thromboembolism ), stroke, dementia and mild cognitive impairment.

The Task Force noted that while the use of Estrogen reduces the risk for fracture, drugs such as bisphosphonates and calcitonin are available and effective in helping prevent fractures in women diagnosed with osteoporosis.

The Task Force concluded that for most women, the harmful effects of Estrogen therapy outweigh any benefits for fracture and other chronic conditions.

In addition, the Task Force reaffirmed its earlier recommendation against the routine use of combined Estrogen and Progestin for preventing chronic conditions in postmenopausal women. Although the combination therapy may reduce risk for fractures in women diagnosed with osteoporosis and for colorectal cancer, it has no beneficial effect on heart disease and may even put women at greater risk for the condition.

Other potential harms of combined Estrogen and Progestin include increased risk for breast cancer, venous thromboembolism, inflammation of the gallbladder, dementia and mild cognitive impairment.

The Task Force concluded that the harmful effects of combined Estrogen and Progestin are likely to exceed the chronic disease prevention benefits for most women.

The Task Force did not examine the effects of Estrogen only or combined Estrogen and Progestin for the treatment of menopausal symptoms, only for the prevention of chronic disease.
Menopause occurs in most women in the United States between 41 to 59 years of age, although the body’s production of Estrogen and Progestin may begin to decrease years before.
The average woman going through menopause has a 46 percent likelihood of developing heart disease over her lifetime, a 20 percent likelihood of stroke, a 15 percent likelihood of bone fracture, and a 10 percent chance of developing breast cancer.

Source: AHRQ, 2005
 
 
 
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