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Recent News and Articles on the Keywords: new + osteoporosis + 0.37  Related to the article below (Last Update: 8/5/2008)

LOCAL UPDATES
Grand Forks Herald, ND -
My New View: RiverView Health?s My New View program will host ?Osteoporosis: It?s Beatable. It?s Treatable? from 3 to 6 pm Thursday on the main RiverView ...
More soy, less sperm? New study in the journal Human Reproduction ...
Los Angeles Times, CA -
It's also, of course, been praised -- as a way to prevent prostate and breast cancers, osteoporosis, hot flashes and heart disease. The pendulum will likely ...
Evaluation of Patients with a recent Clinical Fracture and ...
7thSpace Interactive (press release), NY - 14 minutes ago
... presence of contributors to secondary osteoporosis. Results: In 27 patients, 34 contributors were previously known, in 50 patients 52 new contributors ...
Millions worldwide suffer from osteoporosis
SINDH TODAY, Pakistan -
Sydney, Aug 5 (IANS) Osteoporosis, that causes bones to become fragile, weak and increasingly fracture-prone, affects millions worldwide, says a new report. ...

Daily Mail
Doctor, I've got a bone to pick with you... The bone problems that ...
Daily Mail, UK -
This can lead to problems such as osteoporosis, while Paget's disease causes the cells that make new bone to work too quickly, throwing down new cells even ...

Daily Mail
It's NOT all hokum! A new book reveals which herbal remedies work ...
Daily Mail, UK -
INEFFECTIVE: No evidence that evening primrose oil prevents hot flushes or osteoporosis. The Chinese herbal preparation dong quai, which is thought to have ...
Ligand Pharmaceuticals Appoints Dr. Stephen Sabba to Board of ...
MarketWatch -
... and develops new drugs that address critical unmet medical needs of patients with thrombocytopenia, hepatitis C, hormone-related diseases, osteoporosis, ...LGND
Stop prostate exams at age 75, federal panel recommends
Los Angeles Times, CA - 14 minutes ago
The new guidelines go one step further, saying, in effect, why test if the patient is unlikely to be treated? The recommendations could therefore trigger a ...
Is the new test for osteoporosis better than a bone density test?
Boston Globe, United States - Jul 28, 2008
The test will "simplify osteoporosis diagnosis for busy primary care physicians," said Mary Bouxsein, who studies the biomechanics of bone strength at Beth ...

HealthJockey.com
Study Says It's Not Too Late for Kids to Strengthen Bones
FOXBusiness - Aug 2, 2008
These new findings show that for those children who have inadequate calcium intake, meeting calcium recommendations may help reduce the risk of osteoporosis ...
Study: Improve Your Kids' Bones By Including Enough Calcium TheMedGuru
Calcium-Rich Diet Strengthens Kids? Bones MedHeadlines
Calcium May Strengthen Kids' Bone Health, Says Researchers TopNews
HealthJockey.com
all 17 news articles »
Source: Google News

… of trace minerals in the pathogenesis of postmenopausal osteoporosis and a new effect of calcitonin -
A G?r, L ?olpan, K Nas, R ?evik, J Sara?, F … - Journal of Bone and Mineral Metabolism, 2002 - Springer
... Serum Zn 1.22 0.31 0.609 0.37* 0.646 0.34* , ** 0.765 ... Lippincott-Raven, New York,
pp 41?46 ... al.: Trace minerals in postmenopausal osteoporosis and calcitonin ...

A new tracer method for the calculation of rates of bone formation and breakdown in osteoporosis and … -
J Reeve, R Hesp, R Wootton - Calcified Tissue International, 1977 - Springer
... These 18 new sets of data were then analysed to ... Calculation of Bone Formation and
Breakdown in Osteoporosis ... 60 80 (a) laaBa 0.0 a 0.45 0.28 --0.45 --0.37 ...

What's new in preventing and treating osteoporosis -
WC Andrews - Postgrad Med, 1998 - postgradmed.com
... protective effect, with a relative risk of 0.37 (CI, 0.13 ... It is reasonable to anticipate
five to ten new therapies for osteoporosis becoming available ...
-

IX: Summary of Meta-Analyses of Therapies for Postmenopausal Osteoporosis -
A Cranney, G Guyatt, L Griffith, G Wells, P … - Endocrine Reviews, 2002 - Endocrine Soc
... vitamin D is 0.0012 x 0.37 = 0.000444 (0.04 ... predict hip fractures and new vertebral
deformities ... of etidronate for the treatment of postmenopausal osteoporosis. ...

Assessment of a New Quantitative Ultrasound Calcaneus Measurement: Precision and Discrimination of … -
YQ He, B Fan, D Hans, J Li, CY Wu, CF Njeh, S Zhao … - Osteoporosis International, 2000 - Springer
... SOS ? Sahara 0.001+0.0004 (gs/cm 2 m) 0.37 <0.01 ... of ultrsound in the assessment of
osteoporosis: a review ... Cummings S, Genant H. Searching for new and improved ...

Application of a New Serum Assay for Type I Collagen Cross-Linked N-Telopeptides: Assessment of … -
BJ Gertz - Calcified Tissue International, 1998 - Springer
... of ~33% (10.08 ? 0.71 versus 6.75 ? 0.37 nmol BCE ... In: Riggs BL, Melton LJ III,
(eds) Osteoporosis. Raven Press, New York, pp 297?316 3. Seibel MJ, Robins ...

… influence the success of calcitriol therapy for recurrent vertebral fracture in osteoporosis. -
NA Morrison, PM George, T Vaughan, MW Tilyard, CM … - Pharmacogenetics and Genomics, 2005 - jpharmacogenetics.com
... trial when treated with calcitriol (OR=0.37, 95% CI ... Because the new fracture rate
is low in the ... originally suggested to protect against osteoporosis [17]: the ...

2MD, a new anabolic agent for osteoporosis treatment -
LA Plum, LA Fitzpatrick, X Ma, NC Binkley, JB … - Osteoporosis International, 2006 - Springer
... ORIGINAL ARTICLE 2MD, a new anabolic agent for osteoporosis treatment LA Plum .
LA Fitzpatrick . X. Ma . NC Binkley . JB Zella . M. Clagett-Dame . HF DeLuca ...

A randomized trial of sodium fluoride as a treatment for postmenopausal osteoporosis -
M Kleerekoper, EL Peterson, DA Nelson, E Phillips, … - Osteoporosis International, 1991 - Springer
... Fluoride 42 111.13 5 45 0.48 (0.10-2.39) 0.37 ... P. Long-term fluoride therapy of
postmenopausal osteoporosis. ... New York: Wiley, 1977: chapter 6. 7. Laird NM, Ware ...

IV. Meta-Analysis of Raloxifene for the Prevention and Treatment of Postmenopausal Osteoporosis -
A Cranney, P Tugwell, N Zytaruk, V Robinson, B … - Endocrine Reviews, 2002 - Endocrine Soc
... Lufkin trial 0.52 (95% CI 0.12?2.18, P = 0.37) (6, 14 ... Med Assoc J Home page ER Yendt
Osteoporosis guidelines Can ... Alert me when: new articles cite this article. ...

Source: Google Scholar
 
 

Cannabinoid receptor blockers, new drugs for osteoporosis ?

 

 
Researchers at University of Aberdeen have made a finding that could pave the way for new drugs to treat osteoporosis and other bone diseases.

Their studies also suggest that cannabis use might affect users’ bone health, although researchers stress that further research would be required to confirm this.

As part of an Arthritis Research Campaign funded study into brittle bones and other diseases, the research team explored the effects of chemicals produced naturally in our body called endogenous cannabinoids on bone.

Cannabinoids act in the same way that cannabis does by attaching themselves to receptors in our body which then play a part in a number of the body’s processes including controlling our appetite.

The researchers reveal their discovery that these receptors are also present in bone cells and play a crucial role in regulating bone density and bone turnover.

They also discovered that if they used drugs to block the cannabinoid receptors, this was highly effective in preventing bone loss.

Stuart Ralston, who led the research project, and is now based at the University of Edinburgh, said: “ This is an important finding since it demonstrates that the receptors which cannabis acts upon are not only important in the nervous system, but also in the control of bone metabolism.

“ The fact that compounds which blocked cannabinoid receptors are highly effective at preventing bone loss is particularly exciting, since it shows that these drugs could provide us with a completely new approach to the treatment of osteoporosis and other bone diseases. “

Ruth Ross, who is a cannabinoid research scientist at the University of Aberdeen, added: “ Cannabinoid receptor blockers have recently been shown to be safe and effective for the treatment of obesity. The fact that they may also be potent inhibitors of bone loss has major therapeutic implications. "

Conversely, the researchers also discovered that drugs which stimulate these receptors - and mimic the effects of cannabis – were detrimental to bone and caused increased bone loss, which could, in turn lead to osteoporosis.

However, the most widely used of drug treatments for osteoporosis, cancer-related bone diseases, rheumatoid arthritis and other bone diseases are inconvenient to take and can be associated with various undesirable side effects.

Source: University of Aberdeen, 2005
 
 
 
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