The angry breast cancer survivors Macleans.ca, Canada - Nov 20, 2008 Rakovitch believes post-treatment life is the next step in breast cancer research, noting studies are under way on the use of Ritalin to ease chemobrain. ...
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Recent News and Articles on the Keywords: cancer + beat + fatigue Related to the article below (Last Update: 8/7/2008)
Teens make the most of their vacation Sudbury Town Crier, MA - "Kids who have beat cancer hold up signs that say, ?Thanks to you I?m here.? It?s very emotional." Ray?s father, Jeff, is a five-time rider in the Pan-Mass ...
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[BOOK]Handbook of Cancer-Related Fatigue - R Patarca-Montero - 2004 - haworthpress.com ... suf- ferers of not only cancer but also ... Colloquial jargon to refer to fatigue states
also changes ... pink?; today they are ?bushed,? ?beat,? or ?washed ... -
The drug methylphenidate -- more commonly known as Ritalin, Concerta, Metadate, or Methylin -- can help cancer patients fight off fatigue, according to researchers from M.D. Anderson Cancer Center in Houston. The best effect comes from taking small doses throughout the day, they report in the Journal of Clinical Oncology (Vol. 21, No. 23: 4439-4443).
Most patients with advanced cancer will experience fatigue, a symptom that can destroy quality of life. Although the fatigue sometimes stems from anemia and improves with increases in blood counts, most often there is no specific cause and no ready treatment.
Methylphenidate is typically prescribed for ADHD, or attention deficit/hyperactivity disorder, but it has been used, with some success, to treat cancer fatigue. In this study, the researchers wanted to better document this success by measuring symptom improvement through the use of specially designed questionnaires.
Patients Felt Better Physically and Emotionally
The researchers enrolled 30 patients with advanced cancer and fatigue; the participants were given a one-week supply of 5-mg methylphenidate tablets and told to take them as needed for fatigue. After 7 days they had the option of stopping the medication or continuing for 3 more weeks. All the patients reported that the drug helped and all chose to continue taking it.
The researchers also found other evidence that the drug was helping. At the beginning of the study, the patients rated their fatigue on a 0-10 scale, with 10 being the worst. The average was 7.2. After 28 days of methylphenidate, their fatigue level had dropped to 4.4.
The patients also reported less depression and greater physical and emotional well-being. When the researchers measured patient fatigue during the day, they noted a drop from morning to evening as the effects of that day's treatment took hold.
Side Effects Minor
Side effects weren't a big problem. Two patients reported restlessness. Two others reported a loss of appetite, although most actually found their appetites improved.
The authors acknowledge that bigger studies are needed to understand why methylphenidate works, how long it remains effective, and how long it can safely be taken. But they were encouraged by the clear-cut benefit of the drug in improving both the fatigue and the quality of life of these patients.
