Helicobacter pylori: Friend and Foe? Medscape - Nov 21, 2008 Cure of Helicobacter pylori infection in patients with reflux oesophagitis treated with long term omeprazole reverses gastritis without exacerbation of ...
Slovenian synthetic biologists win competition at MIT Cordis News, Belgium - Nov 28, 2008 Effective vaccine against Helicobacter pylori is not available, although it could be a durable solution, particularly in a formulation affordable to the ...
How Chronic Inflammation Can Lead To Stomach Cancer Science Daily (press release) - Nov 5, 2008 "This study shows that accumulation of IL-1β, which is induced by infection with the bacterium Helicobacter pylori (H. pylori) in the gastrointestinal tract ...
Prevention is better than the cure for cancer Merinews, India - Nov 17, 2008 Helicobacter pylori infection of the stomach appears to be an important cause of gastric ulcers. 2. Chronic duodenal ulcer, this is a common condition of ...
Gutsy doc?s eureka moment Sun2Surf, Malaysia - Nov 12, 2008 By acting as his own guinea pig, Marshall had proven otherwise ? that it is the H pylori, that could bring on ulcers and gastritis and the world at large ...
Eradicating a bad bacteria Macleans.ca, Canada - Nov 6, 2008 The culprit, residents believed, was a common bacteria: Helicobacter pylori. The spiral-shaped bug, which lives in the human stomach or intestine, ...
Indian infection Daily News & Analysis, India - Nov 8, 2008 Ninety per cent of the population is exposed to H. Pylori bacteria, which is the leading cause for chronic gastritis in India,? found Dr HG Desai in his ...
A Jamboree With Reusable Parts Chemical & Engineering News - Nov 16, 2008 The Slovenia team won the grand prize at iGEM 2008 for its design of a vaccine to fight Helicobacter pylori, a bacterium that causes gastritis and ulcers. ...
Farmers tired of Bolante's fake illness Philippine Star, Philippines - Nov 4, 2008 ... series of tests done on Bolante showed ?the presence of multiple gastric ulcers, esophagitis, and erosive gastritis, which tested positive for H-pylori. ...
FARMERS TIRED OF BOLANTE'S FAKE ILLNESS Philippine Headline News, Philippines - Nov 6, 2008 ... series of tests done on Bolante showed ?the presence of multiple gastric ulcers, esophagitis, and erosive gastritis, which tested positive for H-pylori. ...
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Recent News and Articles on the Keywords: h pylori + h. pylori + pylori Related to the article below (Last Update: 8/7/2008)
Targeting focal adhesions: Helicobacter pylori-host communication ... 7thSpace Interactive (press release), NY - Aug 5, 2008 The human pathogen Helicobacter pylori (H. pylori) directly targets integrins with drastic consequences on the epithelial cell morphology and migration, ...
Helicobacter pylori and Peptic Ulcer The New Nation, Bangladesh - Aug 2, 2008 Helicobacter pylori (H. pylori) is a type of bacteria. Researchers believe that H. pylori is responsible for the majority of peptic ulcers. H. pylori...
Helicobacter pylori infection and the risk of gastric carcinoma. - J Parsonnet, GD Friedman, DP Vandersteen, Y Chang, … - New England Journal of Medicine, 1991 - content.nejm.org ... (2005). Activation of {beta}-catenin by carcinogenic Helicobacterpylori. Proc.
Natl. Acad. Sci. ...Hpylori colocalises with MUC5AC in the human stomach. ...
The complete genome sequence of the gastric pathogen Helicobacter pylori - JF Tomb, O White, AR Kerlavage, RA Clayton, GG … - Nature, 1997 - palgrave-journals.com ... value of complete genome sequence information for drug discovery and vaccine
development, we have sequenced the genome of a representative H.pylori strain by ...
Helicobacter pylori Infection and the Development of Gastric Cancer - N Uemura, S Okamoto, S Yamamoto, N Matsumura, S … - New England Journal of Medicine, 2001 - content.nejm.org ... patients who had duodenal ulcers, gastric ulcers, gastric hyperplasia, or nonulcer
dyspepsia at the time of enrollment; 1246 had H. pylori infection and 280 ...
Helicobacter pylori infection and gastric lymphoma - J Parsonnet, S Hansen, L Rodriguez, AB Gelb, RA … - New England Journal of Medicine, 1994 - content.nejm.org ... Randomised trial of endoscopy with testing for Helicobacterpylori compared with
non-invasive Hpylori testing alone in the management of dyspepsia. ...
Helicobacter pylori infection induces gastric cancer in Mongolian gerbils - T Watanabe, M Tada, H Nagai, S Sasaki, M Nakao - Gastroenterology, 1998 - Elsevier ...H. pylori TN2GF4 used in this study had been isolated from a patient with gastric
ulcer and was motile and urease, catalase, and oxidase positive. ...
Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. - A Nomura, GN Stemmermann, PH Chyou, I Kato, GI … - New England Journal of Medicine, 1991 - content.nejm.org ... Next Next. Helicobacterpylori infection and gastric carcinoma among Japanese Americans
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Helicobacter pylori
The bacteria H. pylori (Helicobacter pylori) usually don't cause problems in childhood. However, if left untreated the bacteria can lead to digestive illnesses, including gastritis (the irritation and inflammation of the lining of the stomach), peptic ulcer disease (characterized by sores that form in the stomach or the upper part of the small intestine, called the duodenum), and even stomach cancer later in life.
But even though the bacteria can cause these illnesses, experts believe that most H. pylori infections are "silent" and produce no symptoms.
The bacteria are found everywhere in the world, but especially in developing countries, where up to 10% of children and 80% of adults can have laboratory evidence of an H. pylori infection - usually without having any symptoms.
In industrialized countries, the infection is rare in children, and only about 40% of adults are infected. The risk of infection is higher for those who live in overcrowded or unsanitary conditions.
What Are the Signs and Symptoms?
Anyone, including a child, can have an H. pylori infection without knowing it. When the bacteria do cause symptoms, they're usually either symptoms of gastritis or peptic ulcer disease.
In children, symptoms of gastritis may include nausea, vomiting, and frequent complaints about pain in the abdomen. However, these symptoms are seen in many childhood illnesses.
H. pylori, which used to be called Campylobacter pylori, can also cause peptic ulcers (commonly known as stomach ulcers). In older children and adults, the most common symptom of peptic ulcer disease is a gnawing or burning pain in the abdomen, usually in the area below the ribs and above the navel. This pain typically gets worse when someone with ulcers has an empty stomach and improves as soon as he or she eats food, drinks milk, or takes antacid medicine.
Children who have peptic ulcer disease can have ulcers that bleed, causing hematemesis (bloody vomit or vomit that looks like coffee grounds) or melena (stool that's black, bloody, or looks like tar). Younger children with peptic ulcer disease may not have symptoms as clear-cut as those of older children, and their illness may be harder to diagnose.
Is It Contagious?
Scientists suspect that H. pylori infection may be contagious, because the infection seems to run in families and is more common where people live in crowded or unsanitary conditions. Although research suggests that infection is passed from person to person, exactly how this happens isn't really known.
How Is It Diagnosed?
Doctors can make the diagnosis of an H. pylori infection by using many different types of tests. Your child's doctor may:
look at the stomach lining directly with an instrument called an endoscope. This procedure is performed under sedation and involves inserting an endoscope - a small, flexible tube with a tiny camera on the end - down your child's throat and into the stomach and duodenum. The doctor may then take samples of the lining to be checked in the laboratory for microscopic signs of infection and for H. pylori bacteria.
do blood tests, which can detect the presence of H. pylori antibodies. Blood tests are common, although they typically aren't as accurate for children as they are for adults.
do breath tests, which can detect carbon broken down by H. pylori after the patient drinks a solution. But breath tests are also used mostly in adults.
How Is It Treated?
Doctors treat H. pylori infections using antibiotics. Because a single antibiotic may not kill the bacteria, your child may be given a combination of antibiotics.
If your child has symptoms of bleeding from the stomach or small intestine, these symptoms will be treated in a hospital.
Because H. pylori infection can be cured with antibiotics, the most important home treatment is to give your child any prescribed antibiotic medicine on schedule for as long as your child's doctor has directed. Your child's doctor may also give antacids or acid-suppressing drugs to neutralize or block production of stomach acids.
One way to help soothe the abdominal pain of H. pylori infections is by following a regular meal schedule. This means planning meals so that your child's stomach doesn't remain empty for long periods. Eating five or six smaller meals each day may be best, and your child should take some time to rest after each meal.
It's also important to avoid giving your child aspirin, aspirin-containing medicines, ibuprofen, or anti-inflammatory drugs because these may irritate the stomach or cause stomach bleeding.
How Long Does It Last?
With prolonged antibiotic therapy, H. pylori gastritis and peptic ulcer disease (especially ulcers in the duodenum, a portion of the small intestine) can often be cured.
Can It Be Prevented?
Right now, there's no vaccine against H. pylori. And because transmission isn't clearly understood, prevention guidelines aren't yet available. However, it's always important to make sure you and your family:
Wash your hands thoroughly.
Eat food that's been properly prepared.
Drink water from a safe source.
When Should You Call Your Child's Doctor?
Be sure to call your child's doctor immediately if your child has any of the following symptoms:
severe abdominal pain
vomit that's bloody or looks like coffee grounds
stool that's bloody, black, or looks like tar
persistent gnawing or burning pain in the area below the ribs that improves after eating, drinking milk, or taking antacids
However, it's important to remember that there are lots of reasons children can get stomachaches - just a few of them are indigestion, viruses, tension and worry, and appendicitis. Most stomachaches are not caused by H. pylori bacteria.