Recent News and Articles on the Keywords: colon cancer + cancer treatment + cancer  Related to the article below (Last Update: 8/7/2008)


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High Concentrations of Vitamin C Injections Tested to Fight Cancer
eFluxMedia -
There was also some evidence that vitamin D may help prevent colon cancer. However, the study shows the need for more research.
Study Finds Vitamin C May Stop Cancer Growth NBC 10.com
all 163 news articles »
Goldman-Led Genentech's Avastin May Force Higher Bid (Update1)
Bloomberg -
The usual treatment for colon cancer now is surgery to remove the tumor and six months of chemotherapy, followed by annual colonoscopies. ...DNA - OTC:RHHBY - SWF:RO
Cannabis compound clue to colon cancer
New Scientist (subscription), UK -
This opens up a possible two-step treatment for colon cancer. First, switch CB1 back on using decitibine, a drug already approved for use in humans which ...

CTV.ca
Perceived Medical Discrimination May Discourage Cancer Screening
MedPage Today, NJ -
6 -- Perceived discrimination in medical care translated into lower rates of screening for breast and colorectal cancer in minority patients, ...
Prostate cancer rate spurs campaigners So Md News
Why should 75 years old men avoid prostate cancer screening? Food Consumer
Prostate Cancer Screening: Making Decisions Without Evidence Wall Street Journal Blogs
Medscape (subscription) - Earthtimes (press release)
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For swimmer battling cancer, pool is his comfort zone
USA Today -
"You have cancer; it doesn't have you," Rick Shanteau, a lung cancer patient for the last year, told his son. Eric, 24, has been living those words every ...
YM BioSciences stock drops 22 per cent following release of ...
The Canadian Press,  Ont. - Aug 5, 2008
He said one of YM's product licensors has some "highly encouraging" preliminary data on the treatment of brain metastases and non-small cell lung cancer in ...
NOTICE OF YM BIOSCIENCES CONFERENCE CALL TO DISCUSS PHASE II DATA ... MarketWatch
YM BIOSCIENCES ANNOUNCES STAFFING CHANGES Canada NewsWire (press release)
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EntreMed Reports Second Quarter 2008 Financial Results
FOXBusiness -
EntreMed, Inc. is a clinical-stage pharmaceutical company developing therapeutic candidates primarily for the treatment of cancer and inflammation. ...
GeneNews Announces Second Quarter Results PR Newswire (press release)
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Micromet, Inc. Reports Second Quarter 2008 Financial Results
Earthtimes (press release), UK -
7 -- Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company focusing on the development of novel, proprietary antibodies for the treatment of cancer, ...MITI
New Gene Therapy Kills Pancreatic Cancer Cells
Science Daily (press release) - Aug 5, 2008
"We are very excited at the prospect of this chemoprevention gene therapy as a means of both preventing and treating pancreatic cancer, and it has ...OTC:CTHP - BIT:MLM
Cancer: World`s worst killer
Triumph, Nigeria -
The commonest forms of cancer are breast cancer, prostate cancer and skin cancer. Others include lung cancer, colon cancer, endometrial cancer, ...
Source: Google News

… alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial -
JY Douillard, D Cunningham, AD Roth, M Navarro, RD … - The Lancet, 2000 - Elsevier
... tolerated regimens that combine irinotecan and high-dose fluorouracil and calcium
folinate may be beneficial in the first-line treatment of colorectal cancer. ...

… and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer -
A de Gramont, A Figer, M Seymour, M Homerin, A … - Journal of Clinical Oncology, 2000 - jco.ascopubs.org
... examined as adjuvant therapy for colon cancer (Multicenter International Study of
Oxaliplatin 5FU-LV in the Adjuvant Treatment of Colon Cancer) to verify ...

Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer -
H Hurwitz, L Fehrenbacher, W Novotny, T Cartwright … - The New England Journal of Medicine, 2004 - nejm.org
... 4 , 5 In a phase 2 trial of the treatment of colorectal cancer, the addition of
bevacizumab to fluorouracil plus leucovorin 6 increased the response rate, the ...
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… Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer -
D Cunningham, Y Humblet, S Siena, D Khayat, H … - New England Journal of Medicine, 2004 - content.nejm.org
... of cetuximab in combination with irinotecan with that of cetuximab alone in metastatic
colorectal cancer that was refractory to treatment with irinotecan. ...

Cyclooxygenase regulates angiogenesis induced by colon cancer cells -
M Tsujii, S Kawano, S Tsuji, H Sawaoka, M Hori, RN … - Cell, 1998 - journals.indexcopernicus.com
... whether COX-2 expression in colon cancer cells affected ... in which the lower chamber
contained colorectal carcinoma cells ... 2 cells, and NS-398 or aspirin treatment ...

Cancer Statistics, 2005 -
A Jemal, T Murray, E Ward, A Samuels, RC Tiwari, A … - CA: A Cancer Journal for Clinicians, 2005 - Am Cancer Soc
... by triterpenoid B-group soyasaponins in colon cancer cells Carcinogenesis ... with
Implications for Prevention and Treatment of Prostate Cancer Cancer Res ...

… colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial -
AM Lacy, JC Garc?a-Valdecasas, S Delgado, A … - The Lancet, 2002 - Elsevier
... LAC is more effective than OC for treatment of colon cancer in terms of morbidity,
hospital stay, tumour recurrence, and cancer-related survival. ...

… to Chronomodulated Fluorouracil-Leucovorin as First-Line Treatment of Metastatic Colorectal Cancer -
S Giacchetti, B Perpoint, R Zidani, N Le Bail, R … - Journal of Clinical Oncology, 2000 - jco.ascopubs.org
... III Multicenter Randomized Trial of Oxaliplatin Added to Chronomodulated
Fluorouracil?Leucovorin as First-Line Treatment of Metastatic Colorectal Cancer. ...

… Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer -
F Kabbinavar, HI Hurwitz, L Fehrenbacher, NJ … - Journal of Clinical Oncology, 2003 - jco.ascopubs.org
... mouse xenograft model of human colon cancer metastasis ... nude mice injected with human
cancer xenografts has ... compared with antibody or chemotherapy treatment alone ...

Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells -
H Sheng - Cancer Research, 1998 - AACR
... Here we report that PGE2 treatment of human colon cancer cells leads to
increased clonogenicity of HCA-7, but not HCT-116 cells. ...

Source: Google Scholar
 
 

Stopping Chemo Early Doubles Risk of Death from Colon Cancer

For seniors undergoing chemotherapy for colon cancer, seeing treatment through to the end is essential for survival, new research suggests. However, up to one-third of all stage III colon cancer patients do not complete their full chemotherapy regimen, leading to almost twice the risk of death as patients who do.

"Basically we found that if you stop therapy early you get no benefit," said Dr. Alfred Neugut, study author from Columbia University Medical Center.

In a study, Neugut and his colleagues identified over 1,500 stage III colon cancer patients over the age of 64, who began chemotherapy as part of their cancer treatment. All of the patients were prescribed fluorouracil-based adjuvant chemotherapy, standard treatment used to kill any remaining cancer cells after cancer-removing surgery. The treatment may be prescribed in various ways but generally lasts at least six months.

Of these patients, 69 percent continued with treatment for five to seven months, but over 30 percent stopped before four months. While it may seem like four months of chemotherapy would be better than none at all, that's not the case. Those who stopped treatment early lived almost half as long as those who finished. "If you don't get all of the treatment, you don't get all of the benefit," said Neugut.

 

It is not clear why patients do not follow through with chemotherapy, but the researchers discovered that patients who were older, unmarried and had health problems in addition to colon cancer were the most likely to stop treatment early. In an earlier study, Neugut found that most women who discontinue adjuvant chemotherapy for breast cancer were most likely to stop because of the adverse side effects.

For colon cancer, however, Neugut suspects that a variety of factors may play into a person's decision to stop treatment, including side effects of the drug, a patient's overall health and lack of support at home.

 
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