Klutz?s capillaries always at greater risk Lawrence Journal World, KS - I miss those Cabbage Patch melees of 1983. It?s just that I bruise too easily to be in the game. For as long as I can remember, my limbs have been peppered ...
Hector Elizondo: Caring for a Loved One with Alzheimer's Dementia HispanicBusiness.com (press release), CA - Nov 21, 2008 ... such as the Exelon(R)Patch (rivastigmine transdermal system), which is the first and only skin patch for the treatment of mild to moderate Alzheimer's...
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Chapter 9: Tracking the monster leads me north to Illinois Jackson Clarion Ledger, MS - Nov 15, 2008 In December, she donated a patch of skin to Dr. Kimonis' research for more tests on the family disease. A smile crosses her face. "Guess who's in line to be ...
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Recent News and Articles on the Keywords: patch + alzheimers + skin Related to the article below (Last Update: 8/7/2008)
Skin patch helps reduce woman's affair paranoia Electric New Paper, Singapore - Jul 24, 2008 He prescribed a medicated patch (Exelon Patch), the only skin patch approved for the treatment of mild to moderately severe Alzheimer's dementia here. ...
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Alzheimer's skin patch 'reduces drug side effects'
Alzheimer's patients may soon be given a tried and tested drug through a skin patch to treat the creeping brain degeneration.
The patch infuses the drug Exelon through the patient's skin. "It would be good to have an alternative" to oral medication, said research leader Dr Bengt Winblad of Sweden's Karolinska Institute, who led the patch research. "It's a useful approach, a new treatment strategy that would be very appreciated not only by the patients, but the caregivers."
Alzheimer's affects 500,000 people in the UK. It gradually robs sufferers of their memories and ability to care for themselves, eventually killing them.
There is no known cure or prevention; today's drugs only temporarily treat symptoms. Exelon does that by inhibiting the breakdown of a brain chemical called acetylcholine, which is vital for nerve cells to communicate with each other. The longer acetylcholine sticks around, the longer those cells can call up memories.
But it can be hard to get Alzheimer's patients to swallow pills, and Exelon can cause serious nausea and vomiting. Applied once a day, the new skin patch sends Exelon straight into the bloodstream, bypassing the gastrointestinal tract in hopes of fewer side effects, and maintaining a consistent daylong dose.
The Novartis-funded study found the low-dose patch was just as effective as the high-dose pills - but pill users suffered three times more nausea and vomiting than patch users.
The patch headlines a trio of innovative potential treatments unveiled Wednesday at an international Alzheimer's meeting.
Also under study are a prostate cancer drug that may also help dementia and an immune therapy to ward off the sticky gunk that is Alzheimer's brain-clogging hallmark.