The Role of Traditional Medicine in Drug Discovery OUPblog, New York - Nov 24, 2008 The isolation of the antimalarial drug quinine from the bark of cinchona trees (eg, Cinchona officialinis) was accomplished by the French chemists Pierre- ...
Think research for cancer, think big Martinsburg Journal, WV - Nov 17, 2008 Everyone deserves a chance for that "future" drug that is sitting on the shelf in the research lab screaming "pick me, pick me." Every cancer diagnosis is ...
Police investigate Union student's home lab Jackson Sun, TN - Nov 11, 2008 He said some of Cook's family members have had cancer and noted that some chemicals in certain types of tree bark could be used to treat the condition. ...
Rainforest drugs could cure cancer Sky News Australia, Australia - Nov 13, 2008 It's scientists are trawling the forest in far north Queensland for drugs. Bark, leaves and seeds, that all contain chemicals never seen before are being ...
Low on Crestor? First Consider Natural Means to Lower Inflammation NewsReleaseWire.com (press release) - Nov 12, 2008 New research on fermented extracts such as sweet potato extract, and toyo-FYG, a fermented pine bark extract, has created a stir among integrative medicine ...
Program helps make parents aware of possible drug use by youths Mount Vernon News, OH - Nov 19, 2008 Caesar, a enthusiastic German Shepherd, is trained to find and locate various illegal drugs, Osborn explained, and will scratch and bark at the site of the ...
Can Red Wine in Pill Form Help You Lose Weight? HealthNews, CA - Nov 6, 2008 Resveratrol and the other bioflavoniods and polyphenols are present in large amounts in bark of grape vines, twigs, and leaves. In turn, red wine, ...
Danville Weekly Online Calendar Danville Weekly, CA - Nov 23, 2008 For information, call 1-800-572-BARK (572-2275) or visit www.cci.org. The Contra Costa County Child Abuse Prevention Council needs volunteer speakers for ...
India almond extracts show promise in diabetes, premature ... FreshPlaza, Netherlands - Nov 14, 2008 The leaves, bark, roots, fruit and seeds of Indian almond have been used to effectively reverse blood sugar regulating functions in damaged pancreas of ...
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Recent News and Articles on the Keywords: drug help + cancer drug + cancer Related to the article below (Last Update: 8/7/2008)
Deal could generate more jobs in long run Indianapolis Star, United States - ... a new drug for humans in three years. But the company said it has dozens of compounds in development for a wide array of diseases, including cancer, ...
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… Compared With Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian Cancer. - WP McGuire, WJ Hoskins, MF Brady, PR Kucera, EE … - Obstetrical & Gynecological Survey, 1996 - obgynsurvey.com ... when we are talking about ovarian cancer, the costs ... of responsiveness to various drugs and, thus, help the clinician ... costs about $1400 (for the drug alone--not ...
Smart drugs: Tyrosine kinase inhibitors in cancer therapy - LK Shawver, D Slamon, A Ullrich - Cancer Cell, 2002 - Elsevier ... including reduced likelihood of genetic drug resistance and broad ... an imaging component
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PDGF receptors as cancer drug targets - K Pietras, T Sj?blom, K Rubin, CH Heldin, A ?stman - Cancer Cell, 2003 - Elsevier ... changes in tumor uptake of drugs upon PDGF ... Ingeg?rd Schiller assisted with expert
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Tests on a drug made from tree bark have produced 'conclusive' evidence that it can help beat tumours, scientists revealed yesterday.
Combretastatin, which has been hailed as a potential cancer cure, produced encouraging results when used in patient trials.
This follows laboratory tests which proved it to be 85 per cent effective in combating the disease.
The drug, derived from the bark of the African bush willow tree, has been shown to work by starving tumours of oxygen.
The great hope is that, when combined with radiation therapy, combretastatin could offer an effective weapon against many types of cancer. Speaking at an international cancer conference in America yesterday, specialists said they had no doubt that the drug 'successfully reduces blood flow that feeds malignant tumours'.
Most forms of cancer are caused by tumours, which rely on a supply of blood and create a special network of capillaries - tiny blood vessels - as they grow.
Dr Scot Remick told the International Conference on Molecular Targets and Cancer Therapeutics, meeting in Miami, that combretastatin appears to deprive a tumour of the nutrients it needs to grow while leaving healthy vessels untouched.
Scans of blood flow in patients being treated with the drug showed 'significant reduction in the tumour blood flow' within four to six hours.
'We were able to demonstrate the ability to reduce tumour blood supply at tolerable dosage levels, without traditional toxic side effects,' said Dr Remick. However, used on its own combretastatin leaves an outer rim of cancerous cells which require radiation therapy to kill them off.
A combined drug and radiation therapy could be available to patients in the UK by 2005.
Researchers reported 'definitive and promising' results from the first phase trial, which involved giving combretastatin to 25 patients, Dr Remick told the conference. Several showed positive responses to treatment. One 55-year-old man with an
aggressive form of thyroid cancer underwent 'complete remission' and remains
disease-free more than two years later.
Two patients experienced 'prolonged periods of freedom from progression of their disease'.
A patient with colon cancer remained stable for 19 months, while another with thyroid cancer remained stable for 12 months.
Kate Law, head of science at the Cancer Research Campaign in London, which helped develop the drug with the backing of the American company OXiGENE, said similar tests on British patients had suggested the drug could have negative side effects, including skin pain and diarrhoea.
But she added: 'On the face of it, these latest American trials are encouraging.
'I don't believe that on its own, this drug will be a dramatic answer to cancer. But it may be very useful alongside other therapies, such as radiation.'
Trials of the combined drug and radiation therapy are due to be launched in the U.S. next year.
'We will be watching the results of those trials with interest,' she said.
When British scientists used combretastatin, combined with locally directed radiation treatment, to combat human colon tumours grafted into mice, 85 per cent of the cancers were eliminated.
The therapy has the potential to work on most cancers, including bowel, breast, liver and lung.
Miss Law added that there were several other drugs in the pipeline which combat cancers by starving them of blood and oxygen.
