Cardiologists Debate Expensive Heart Scans New York Times, United States - 50 minutes ago Dr. Joao AC Lima, an associate professor of medicine at Johns Hopkins Medical School and an author of the study, suggested CT angiography, or CTA, could be ...
I-10 bypass west of city urged Arizona Daily Star, AZ - Nov 29, 2008 The bypass would reconnect with I-10 in Pinal County, likely near the Interstate 8 junction. The route could also act as a bypass for Interstate 19 traffic, ...
A Slow Crash and Burn American Spectator - Whereupon I'd lie down, my heart would stop, and I'd sit up in another panic. This could have gone on for hours. I kept it up for about 45 minutes, ...
'I've always been the fat kid' Appeal-Democrat, CA - Nov 30, 2008 31, she's scheduled to undergo gastric bypass surgery, a little more than one year after she began the process that would lead her to rapid weight loss. ...
Florida manhandles Missouri-Kansas City Florida Today, FL - As for Donovan being back in Orlando, he said he doesn't regret his decision to bypass the Magic and return to Florida. He is friends with Magic coach Stan ...
Spanish Springs resident awaits heart transplant Sparks Today, NV - Nov 28, 2008 "I was never in a condition where they could give me a bypass," Wyman said. "It wasn't because of clogged arteries." Wyman said the doctors have told him ...
A Real Bailout for Auto Makers Barron's - Nov 29, 2008 In the end, a prepackaged bankruptcy would be risky and scary. But so is a bypass operation for a heart patient in imminent danger of dying. ...
Source: Google News
Recent News and Articles on the Keywords: bypass + web + 0.22 Related to the article below (Last Update: 8/7/2008)
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Long-term results of coronary artery bypass grafting in patients with renal insufficiency - Y Nakayama, R Sakata, M Ura, T Itoh - The Annals of Thoracic Surgery, 2003 - Soc Thorac Surgeons ... 2/496 located on the World Wide Web at: The ... reports have been published on coronary
artery bypass grafting (CABG ... mellitus 245 (31%) 55 (47%) 35 (42%) 0.018 0.22...
Release of S100B during coronary artery bypass grafting is reduced by off-pump surgery - RE Anderson, LO Hansson, J Vaage - The Annals of Thoracic Surgery, 1999 - Soc Thorac Surgeons ... 67/6/1721 on the World Wide Web at: The ... artery bypass grafting with and without
cardiopulmonary bypass (CPB ... pump and CPB groups reached a maximum level of 0.22...
Leg wound infection after coronary artery bypass grafting: a meta-analysis comparing minimally … - T Athanasiou, O Aziz, P Skapinakis, B Perunovic, J … - The Annals of Thoracic Surgery, 2003 - Soc Thorac Surgeons ... 2141 located on the World Wide Web at: The ... for revascularization in coronary ar-
tery bypass grafting (CABG ... invasive vein harvest group (odds ratio 0.22 with 95 ...
Modified Fontan without use of cardiopulmonary bypass - VKH Tam, BE Miller, K Murphy - The Annals of Thoracic Surgery, 1999 - Soc Thorac Surgeons ... for the open discussion forum on the STS Web site: http ... The child was quickly placed
on cardiopulmonary bypass. ... p 0.22 0.016 12 Hours postop No CPB 10.9 3.4 4.6 ...
Cost-effectiveness of minimally invasive coronary artery bypass surgery - KV Arom, RW Emery, TF Flavin, RJ Petersen - The Annals of Thoracic Surgery, 1999 - Soc Thorac Surgeons ... full/68/4/1562 on the World Wide Web at: The ... by- pass; NS not significant; OPCAB
off pump coronary artery bypass. ... pt) Cryo 0 0.32 0.06 FFP 0 0.22 0.39 Plt 0.18 ...
Source: Google Scholar
Gene injection could end need for heart bypass
A simple jab can revive dead heart tissue and may herald the end of bypasses, saving thousands of lives, say scientists. The treatment, which could take only 30 minutes, increases blood flow through parts of the heart damaged by attacks or clogged by fat. Patients with severe coronary heart disease, whom doctors expected to die at any time, have had their lives transformed by the injection.
'When I met one of my patients before treatment he was at death's door, ' said Dr Richard Schatz, who led a U.S. study into the new therapy. 'Two years after treatment, he remains pain-free and he's digging ditches in his yard.' The breakthrough involves injecting patients with a gene which stimulates the growth of new blood vessels in the heart.
Unveiling the results of the first long-term study of the gene therapy, Dr Schatz, of the Scripps Clinic in San Diego, said the majority of patients reported less severe chest pain. Many too weak even to move around experienced remarkable improvements in their daily lives, he told the American Heart Association's scientific conference in California. The 'one-hit' jab direct into the heart allowed a significant number of patients to stop taking pain-relieving medication.
Experts are so excited by the results they are planning much bigger trials. These will involve a group of patients in the UK, where heart disease claims 140,000 lives a year.
About 100,000 Britons survive a heart attack each year and some 24,000 go on to have bypass surgery.
At least 500 patients die before reaching the operating theatre and thousands more are not suitable for treatment.
Dr Schatz said the long-term trial in the U.S. suggested a gene injection could offer an alternative, safe treatment.
'I'm very comfortable saying this gene therapy is definitely safe,' he said. 'There has never been a complication from the gene itself.'
Patients involved in his study, and another in Boston, Massachusetts, had 'end-stage' coronary heart dis-ease, suffered disabling angina and were at high risk of sudden death.
None of them could be helped by procedures such as bypass surgery or balloon angioplasty.
In Boston, Dr Peter Vale treated 30 patients aged 48 to 74 with the gene, VEGF-1, which controls the production of a protein called vascular endothelial growth factor. This is involved in the growth of new blood vessels.
Two years after the therapy, 27 of the 30 patients reported fewer weekly angina episodes - from an average of 56 to about four. They also reported taking around three painkillers a week instead of an average 60.
'Most of our patients also have had a continued improvement in their ability to function during their daily lives,' said Dr Vale.
In the second study, Dr Schatz reported results of tests on 30 patients aged between 39 and 77 at five different medical centres. They recorded similar, dramatic improvements.
'The question now is why so many of our patients - all but two - are still alive,' said Dr Schatz.
'Studies have shown that 20 to 25 per cent of people with advanced coronary artery disease and this level of angina die each year. So these results are striking.'
To inject the gene, an incision was made in the patient's chest to expose the heart.
Other experts are working on ways to deliver the gene via a thin guide wire threaded into the body via the groin. This would take only half an hour.
Leading cardiologist Dr Duncan Dymond, of St Bartholomew's Hospital, London, said the results were 'incredibly exciting'.
He added: 'We have to be cautious because we need many more trials, but it's looking encouraging. If these results are reproduced elsewhere then it's a huge breakthrough.
'Anything we can do that improves symptoms for people in this situation is wonderful. We are talking about increasing numbers of people.'