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Cancer centres look for alternatives

Cancer Research UK unveiled a multi-million pound programme of clinical research centres to give more patients access to experimental therapies in the hope they can receive the benefits sooner.

The centres have been described as a "melting pot" of doctors and scientists working together to bring the latest treatments to cancer patients.

The first centre was officially launched today at Barts and The London, Queen Mary's School of Medicine and Dentistry.

The charity will launch at least five more centres at its major sites across the UK this year, with the next set to open in Leeds.

The aim of the centres is to get new treatments to patients faster by finding practical applications for the large amount of new biological knowledge that has become available.

The 280 scientists and doctors working with the centre are to concentrate on the "frontiers of cancer research" such as viral treatments and tailored gene therapies.

Because of its location near two internationally-renowned London hospitals, Cancer Research UK said they would have more opportunity than ever to enrol patients into clinical trials for testing pioneering new treatments.

Trials will focus on areas including adult stem cell research, screening and prevention and imagining and targeting of cancers.

Centre costs £11m in first year

In its first year, Cancer Research UK and Queen Mary's will together spend £11 million in the new centre.

At the launch today Cancer Research UK's chief executive Prof Alex Markham said they wanted to improve the collaboration between scientists working in the lab and doctors treating patients.

"We hope this will act as a melting pot for all ideas developed by scientists and enhance the work of both scientists and doctors.

"At the moment collaboration happens in a rather ad hoc way, with no infrastructure to underpin this."

Prof Markham said the programmes was "the beginning of an exciting new strategy for the charity".

"We have generated a huge volume of biological knowledge about cancer.

"By pulling a variety of research programmes together we aim to translate that wealth of information into treatments as quickly as possible."

Experimental therapies

Professor Nick Lemoine, who will be director of the new clinical centre, said by allowing patients access to early phase clinical trials they would have access to "experimental therapies that might offer them a better chance".

He said: "The over-arching theme of the new research programmes at the centre is 'a molecular approach to cancer in patients and populations'.

"Put simply, that means turning our knowledge of the molecules which contribute to cancer into patient therapies we can test in hospitals and new strategies for cancer prevention."

Professor Nick Wright, warden of Barts and The London, Queen Mary's School of Medicine and Dentistry, said much of its effort in cancer research over recent years had been directed at a basic understanding of the disease.

"Our strategy within the Centre, while continuing such essential research, will be to take these recent ideas and translate them, as soon as we can, into direct benefits for patients with cancer.

"This will include not only treatment, but intervention by large trials directed at preventing the development of cancer.

"We are all very excited about our new centre, made possible through a strong collaboration between Cancer Research UK and the school," he added.