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Recent News and Articles on the Keywords: psoriasis + smoking + severity  Related to the article below (Last Update: 12/1/2008)

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Recent News and Articles on the Keywords: psoriasis + severity + smoking  Related to the article below (Last Update: 8/7/2008)

Manhattan Falls Short on Phase II Trial for Psoriasis
FDA news (subscription), VA - Aug 5, 2008
While a primary safety objective was achieved, the data did not demonstrate a significant improvement in the overall severity of lesions or symptoms such as ...OTC:MHAN
When health problems are skin deep
Chester DailyLocal.com,  USA - Aug 4, 2008
Psoriasis, a chronic skin disorder, is one such condition. August is National Psoriasis Month, and several area medical professionals recently shared their ...
Study Reveals Novel LCD Solution Provides Significant Benefits ...
MarketWatch - Jul 31, 2008
The findings, representing interim results for 48 patients, evaluate categorical and mean changes in PASI (Psoriasis Area Severity Index) Improvement as ...
Manhattan Pharmaceuticals Announces Results of Phase 2a Study of ...
MarketWatch - Jul 31, 2008
... demonstrate a statistically significant improvement in the overall disease severity of treatment lesions or signs and symptoms of psoriasis (redness, ...OTC:MHAN
Manhattan Pharmaceuticals reports encouraging results from ...
Pharmaceutical Business Review - Aug 1, 2008
... improvement in the overall disease severity of treatment lesions or signs and symptoms of psoriasis as compared to the vehicle (placebo) gel. ...OTC:MHAN
European Commission Approves Once-Weekly Etanercept for Psoriasis
DG News - Jul 8, 2008
... was measured with patient-reported outcome (PRO) impairment, Dermatology Life Quality Index (DLQI) score, and Psoriasis Area and Severity Index (PASI). ...
European Commission Announces Marketing Authorisation for 50mg ...
PR Newswire UK (press release), UK - Jul 9, 2008
The 318 study design comprised a primary endpoint of 75 per cent improvement in Psoriasis Area and Severity Index (PASI 75) score and included a number of ...
Top-Line Results of Boceprevir Phase II Study Showed High Rate of ...
CNNMoney.com (press release) - Aug 4, 2008
... development or exacerbation of autoimmune disorders including thyroiditis, RA, systemic lupus erythematosus, psoriasis, pulmonary disorders (dyspnea, ...SGP
Regional Factors Driven by Genetic Diversity Add Complexity to ...
PharmaLive.com (press release), PA - Jul 24, 2008
Because of the individual genetic variability underlying the incidence and severity of autoimmune symptoms, regional variations in the market for autoimmune ...
Mom's marathon effort yields a diagnosis
Southtown Star, IL - Jul 20, 2008
Her mother Toni scheduled an appointment with dermatologist Sarah L. Chamlin at Children's Memorial Hospital, who diagnosed the girl with psoriasis. ...
Source: Google News

Relationship Between Smoking and the Clinical Severity of Psoriasis -
C Fortes, S Mastroeni, K Leffondre, F Sampogna, F … - Archives of Dermatology, 2005 - Am Med Assoc
... 28. In men, family history of psoriasis was a stronger prognostic factor
for psoriasis severity than smoking. Our findings are in ...

Cigarette smoking in men may be a risk factor for increased severity of psoriasis of the extremities … -
MA Gupta, AK Gupta, GN Watteel - Br J Dermatol, 1996 - ncbi.nlm.nih.gov
1996 Nov;135(5):859-60. Cigarette smoking in men may be a risk factor for increased
severity of psoriasis of the extremities. Gupta MA, Gupta AK, Watteel GN. ...

Smoking, alcohol and life events related to psoriasis among women -
K POIKOLAINEN, T REUNALA, J KARVONEN - British Journal of Dermatology, 1994 - Blackwell Synergy
... Severity of psoriasis Patients with psoriasis reported significantly more ... the 12
months preceding the examination (Table 3), Neither smoking nor life ...

The impact of psoriasis on quality of life -
LHF de Arruda, APF de Moraes - British Journal of Dermatology, 2001 - Blackwell Synergy
... 16 Smoking is also more common among patients with psoriasis than in ... a new scoring
system for psoriasis may provide an holistic measure of psoriasis severity. ...

A review of the epidemiology of psoriasis vulgaris in the community -
A Plunkett, R Marks - Australasian Journal of Dermatology, 1998 - Blackwell Synergy
... studied include the frequency, severity and morbidity ... been associated with causing
psoriasis or triggering ... in- fectious agents, cigarette smoking and feelings ...

Alcohol, smoking and psoriasis. -
E Higgins - Clin Exp Dermatol, 2000 - ncbi.nlm.nih.gov
... Initial anecdotal evidence that both smoking and drinking have an influence ... in lifestyle
may reduce both the prevalence and severity of psoriasis offers an ...

[CITATION] Risk of Myocardial Infarction in Patients With Psoriasis -
JM Gelfand, AL Neimann, DB Shin, X Wang, DJ … - JAMA: The Journal of the American Medical Association, 2006 - JAMA
... such as diabetes, hyperlipidemia, hypertension, and smoking. ... have indicated that
the severity of rheumatoid ... mediated diseases such as psoriasis and rheumatoid ...

Smoking habits in psoriasis: a case control study -
CM MILLS, ED SRIVASTAVA, IM HARVEY, GL SWIFT, RG … - British Journal of Dermatology, 1992 - Blackwell Synergy
... of smokers.' We have examined smoking habits in ... hundred and fifty patients with
psoriasis living in ... in-patient records, without reference to severity of disease ...

Assessment of depression in subjects with psoriasis vulgaris and lichen planus -
A Akay, A Pekcanlar, KE Bozdag, L Altintas, A … - Journal of the European Academy of Dermatology & Venereology, 2002 - Blackwell Synergy
... between the Beck Depression Inventory (BDI) and the Psoriasis Area and Severity
Index (PASI ... We also highlight the smoking and drinking habits in both ...

Impact of Obesity and Smoking on Psoriasis Presentation and Management -
MD Herron, M Hinckley, MS Hoffman, J Papenfuss, CB … - Archives of Dermatology, 2005 - Am Med Assoc
... Impact of Obesity and Smoking on Psoriasis Presentation and Management ... ABSTRACT,
Objective To study the impact of obesity and smoking on psoriasis. ...

Source: Google Scholar
 
 

Smoking associated with severity of psoriasis

Cigarette smoking is associated with the clinical severity of the skin disease psoriasis, and both smoking and obesity are more prevalent among psoriasis patients.

Psoriasis is a chronic, persistent, lifelong disease characterized by scaly red plaques on the surface of the skin. Although psoriasis is not a life-threatening disease, the disability experienced by patients with psoriasis is comparable with that of patients with other chronic illnesses, such as heart disease, diabetes, cancer, and depression, according to background information in the article. Cigarette smoking is a risk factor for many chronic diseases, including psoriasis, but little is known about the effect of smoking on psoriasis severity.
 
Cristina Fortes, of Istituto Dermopatico dell'Immacolata, Rome, Italy, and colleagues conducted a cross-sectional study to evaluate the association between different components of smoking history and the clinical severity of psoriasis. They analyzed data on 818 adults with psoriasis in inpatient wards of a hospital for skin diseases.

The study is published in the Archives of Dermatology.

" Specifically, patients who smoked more than a pack of cigarettes ( more than 20 cigarettes ) daily had twice the risk of more severe psoriasis compared with those who smoked ten cigarettes or less per day," the authors report.

Cigarette-years, measured as the product of the intensity and duration of smoking, significantly increased the risk of clinically more severe psoriasis. " Separate analyses for men and women showed that the effect of cigarette-years on psoriasis severity was stronger for women than for men, " the authors write.

" Smoking is associated with the clinical severity of psoriasis and highlights the importance of smoking cessation in patients with psoriasis," they conclude.

In another article, published in Archives in Dermatology, researchers report that the prevalence of both smoking and obesity is higher among patients with psoriasis than in the general population.

Mark D. Herron, and colleagues from the University of Utah School of Medicine, Salt Lake City, studied the impact of obesity and smoking on psoriasis. A case series of patients with psoriasis enrolled in the prospective Utah Psoriasis Initiative ( UPI ) was compared with three population databases: the Behavioral Risk Factor Surveillance System of the Utah population, the 1998 patient-member survey from the National Psoriasis Foundation, and 500 adult patients who attend the University of Utah Department of Dermatology clinics and do not have psoriasis.

" The prevalence of obesity in patients within the UPI population was higher than that in the general Utah population ( 34 percent vs. 18 percent ) and higher than that in the non-psoriatic population attending our clinics," the authors write. " The prevalence of smoking in the UPI population was higher than in the general Utah population ( 37 percent vs. 13 percent ) and higher than in the non-psoriatic population."

The authors found that obesity appears to be the consequence of psoriasis, and not a risk factor for onset of the disease. " Smoking appears to have a role in the onset of psoriasis, but obesity does not," they write.

" It seems certain that the cost of providing care for psoriasis – when coupled with the increased frequency of obesity and smoking in patients attending clinics such as ours – will continue to increase," the authors conclude. " An effort to control obesity and smoking in psoriasis patients and an increased appreciation of the effects of these comorbidities are clearly needed."

Source: American Medical Association, 2005
 
 
 
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