A study of lymph node ratio in stage IV colorectal cancer 7thSpace Interactive (press release), NY - The finding of metastasis in colorectal cancer, stage IV disease, has a major impact on prognosis and treatment strategy. Known important factors include ...
Cancer survivor gives thanks Detroit Free Press, United States - Nov 27, 2008 Because of a rare genetic predisposition to a particular kind of colorectal cancer, Kraus feared the same fate awaited her. But surgeons at Karmanos Cancer...
Lung Cancer Risk Following Detection of Pulmonary Scarring by ... Archives of Internal Medicine - Nov 24, 2008 Methods Cohort analysis of data from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. We included 66 863 cancer-free trial participants ...
Myriad Genetics: Profits In Predictive Medicine istockAnalyst.com (press release), OR - MYGN has tests for a predisposition for breast cancer, ovarian cancer, melanoma, and colorectal cancer. "Using the specific genetic characteristics of an ...MYGN
Living longer with cancer Wyoming Tribune, WY - Nov 29, 2008 Lawyer said screenings can catch an abnormal tissue growth before it becomes colorectal cancer. A push for cessation programs in Wyoming gives more people ...
Source: Google News
Recent News and Articles on the Keywords: cancer risk + colorectal cancer + cancer Related to the article below (Last Update: 8/7/2008)
Exercise Lowers Risk of Colon Cancer U.S. News & World Report, DC - 6 (HealthDay News) -- Physical activity can reduce the risk of colon cancer, but few American adults are aware of this, a new study shows. ...
Sticking to diet advice cuts colon cancer risk Reuters - She and her colleagues looked at the relationship between diet pattern and colorectal cancer risk in 492382 men and women participating in the National ...
Colossal Colon on display at Indiana State Fair Terre Haute Tribune Star, IN - 17 for a study called PROGRESS (PROstate Cancer ? Genetic Risk Evaluation of SNPs Study), which seeks to identify genetic risk factors that contribute to ...
Benefits of colonoscopy far outweigh minimal risks Asbury Park Press, NJ - Colonoscopy remains the gold standard for colorectal cancer screening. Any patient undergoing a medical procedure signs an informed consent stating the ...
High Milk Intake May Boost Ovarian Cancer Risk Online - International News Network, Pakistan - "In contrast, there is strong evidence that milk consumption (and a high intake of calcium, which is found in milk) may reduce the risk of colorectal cancer...
THC-like drug aids prevention of colon cancer UT The Daily Texan, TX - Aug 5, 2008 By Ashley Crooks Compounds similar to THC, the active ingredient in cannabis plants, may aid in the prevention and treatment of colon cancer, according to a ...
? Colonoscopy history WHOI, IL - It?s also the second leading cause of cancer death (following lung cancer), killing about 49960 men and women this year. The risk for colorectal cancer...
Dietary Fiber and the Risk of Colorectal Cancer and Adenoma in Women - CS Fuchs, EL Giovannucci, GA Colditz, DJ Hunter, … - New England Journal of Medicine, 1999 - content.nejm.org ... Diet and colorectalcancerrisk: Baseline dietary knowledge of colorectal patients. ...
Major Dietary Patterns and the Risk of ColorectalCancer in Women. ...
Aspirin Use and the Risk for Colorectal Cancer and Adenoma in Male Health Professionals - E Giovannucci, EB Rimm, MJ Stampfer, GA Colditz, A … - Annals of Internal Medicine, 1994 - annals.highwire.org ...Colorectalcancerrisk, chronic illnesses, operations and medications: case control
results from the Melbourne ColorectalCancer Study. Cancer. ...
Alcohol, Low-Methionine-Low-Folate Diets, and Risk of Colon Cancer in Men - E Giovannucci, EB Rimm, A Ascherio, MJ Stampfer, … - jnci, 1995 - jnci.oxfordjournals.org ... Lee, and JE Buring Folate, Vitamin B6, Multivitamin Supplements, and Colorectal CancerRisk in Women Am. J. Epidemiol., January 15, 2006; 163(2): 108 - 115. ...
Aspirin and the risk of colorectal cancer in women - E Giovannucci, KM Egan, DJ Hunter, MJ Stampfer, GA … - New England Journal of Medicine, 1995 - content.nejm.org ... Dietary Glycemic Load, Carbohydrate, Sugar, and ColorectalCancerRisk in Men
and Women. ... Aspirin and the Risk of ColorectalCancer in Women. ...
Source: Google Scholar
Statins not associated with reduced colorectal cancer risk
A study, published in the Journal of the National Cancer Institute, found that use of cholesterol reducing drugs is not associated with a reduced risk of colorectal cancer.
Previous studies have investigated the association between statins, the most commonly used type of cholesterol lowering drug, and colorectal cancer incidence, but these studies have produced mixed results.
Several randomized trials, generally considered the most reliable type of study, found no clear association between statin use and colorectal cancer, but these trials were relatively small and did not examine long-term statin use.
In contrast, a recent large study, the Molecular Epidemiology of Colorectal Cancer ( MECC ) study, which included almost 4000 people, showed that statin use for a period of more than 5 years was associated with a 47% reduction in the risk of colorectal cancer.
Eric J. Jacobs, of the American Cancer Society in Atlanta, and colleagues investigated the association between use of cholesterol-lowering drugs and colorectal cancer risk in the 132,136 men and women enrolled in the Cancer Prevention Study II Nutrition Cohort.
Researchers identified 815 cases of colorectal cancer in cohort participants during the period from 1997 to 2001. They found that use of cholesterol-lowering drugs, even use for 5 or more years, was not associated with colorectal cancer incidence.
This study measured use of cholesterol lowering drugs in general rather than use of statins in particular. However, the authors note that if statins strongly reduced the risk of colorectal cancer, use of any cholesterol-lowering drugs would likely have been associated with some reduction in risk because most users of cholesterol lowering drugs use statins.
" Our results do not support the hypothesis that statins, as a class of drugs, strongly reduce risk of colorectal cancer," they write.
In an accompanying editorial, John McLaughlin, of Cancer Care Ontario and the Prosserman Centre for Health Research in Ontario, calls the study a "prompt and timely contribution to the literature, because it capitalized on the existence of a large and well-characterized cohort." He writes that the study results suggest that a clinical trial that evaluates statins as a chemopreventive agent would be premature and that the results show that large cohort studies provide an excellent resource for hypothesis testing.
Source: Journal of the National Cancer Institute, 2006
