Physicians open eyes to medical issues of sleep Fort Worth Business Press, TX - Bad sleep ? and sleep apnea, one of the leading causes of bad sleep ? can exacerbate a whole host of health problems, and physicians are referring patients ...
Health Matters Sleep Disorders LocalNews8.com, ID - Sleep apnea - This potentially life-threatening disorder is linked to irregular heartbeat, high blood pressure and heart failure. Sleep apnea can cause you ...
Baby boomers plagued by sleep disorders Mohave Valley News, NV - ?Now one of the major findings in sleep medicine has been the recognition that if you treat sleep apnea, you can prevent cardiovascular disease. ...
Doctor drifts into snoring business Dallas Morning News, TX - Nov 30, 2008 Craig can sell." Dr. Schwimmer doesn't claim that the Pillar procedure is perfect. "Up to 80 percent of sleep apnea patients have clinically significant ...
Slumber the Pounds Away KUNC, CO - To make matters worse, sleep apnea is related to obesity. So if you don't sleep enough you can gain weight and, when you gain weight you are more likely to ...
Healthy Families, Healthy Homes: Sleep Apnea KFYR-TV, ND - Nov 24, 2008 Many people do not realize their sleep is being affected. They go years without seeing a doctor. Living tired becomes the norm for many. Sleep apnea can be ...
Airspan Announces Second Quarter 2008 Results FOXBusiness - Airspan is the industry's leading WiMAX pure player, ranked #1 for IEEE802.16-2004 WiMAX revenue in 2007 and has now been selected for some of the world's ...AIRN
Douglas Emmett, Inc. Announces 2008 Second Quarter Earnings Results Trading Markets (press release), CA - Aug 5, 2008 Interested parties can access the call via the Internet by going to the Investor Relations section of the Company's Web site at www.douglasemmett.com or by ...DEI
Sun Healthcare Group, Inc. Reports Second Quarter Earnings ... Trading Markets (press release), CA - Any documents filed by Sun with the SEC may be obtained free of charge at the SEC's web site at www.sec.gov. In addition, investors and stockholders of Sun ...SUNH
Allos Therapeutics Reports 2008 Second Quarter Results MarketWatch - Aug 5, 2008 The webcast will be available from the homepage and the investors/media section of the Company's web site at www.allos.com and will be archived for 30 days. ...ALTH
June 2008 Quarterly Activities and Cashflow Report Sydney Morning Herald, Australia - Jul 21, 2008 Results included: - BL08-15: 34m @ 2.12g/t Pt+Pd, 0.29% Cu & 0.21% Ni from 138m, including 11m @ 3.15g/t Pt+Pd, 0.40% Cu & 0.25% Ni - BL08-39: 28m @ 2.22g/t ...ASX:MMB
EPL Announces Second Quarter 2008 Results StreetInsider.com (subscription), MI - Aug 5, 2008 The conference call will be webcast live as well as for on-demand listening at the Company's web site, www.eplweb.com. Listeners may access the call through ...EPL - NBL
Are Dividends the Cure for Your Ailing Portfolio? Morningstar.com, IL - Jul 29, 2008 It recently got a new manager, Michael Reckmeyer, but its ultralow 0.29% expense ratio means that it's still one of our favorites. ...
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terms reflect interest in ... The Web query vocabulary contains a very large ...
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of 0.69 0.64 0.61 0.50 0.48 0.45 0.44 0.42 0.36 0.34 0.33 0.29 0.28 0.27 ...
Real life information retrieval: a study of user queries on the Web - BJ Jansen, A Spink, J Bateman, T Saracevic - ACM SIGIR Forum, 1998 - portal.acm.org ... that have a frequency of 11,577 occurrences - that is 0.29% of unique ...Web queries
are short. ... Queries in searching of regular IR systems are some three to ...
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Prader-Willi syndrome: growth hormone can worsen sleep apnea in some children
Researchers at the University of Florida ( UF ) have that growth hormone treatment can worsen a dangerous nighttime breathing problem.
Sleep apnea disrupts breathing during sleep and is common among morbidly obese children, including those with Prader-Willi syndrome, a disease that compels them to eat nonstop.
Growth hormone has shown to be one of the most effective ways to treat children and adults with Prader-Willi. But UF researchers found that starting treatments can worsen or trigger sleep apnea in obese children exposed to colds, potentially leading to death.
The findings are published in The Journal of Clinical Endocrinology and Metabolism.
" Every kid we studied had abnormal sleep at the beginning, before growth hormone," said Jennifer Miller, lead author. " On growth hormone, most of them got better but not all of them. The ones that got worse tended to be school age. Some of them were just entering school and then they were coming home with upper-respiratory infections.
" The combination of starting growth hormone, still having weak muscle tone, having an illness and/or being obese tends to put you at risk for having really bad obstructive sleep apnea."
The researchers urge doctors to monitor patients' sleep before and during treatment for signs of obstructive sleep apnea, such as loud snoring or abnormal daytime sleepiness. Sleep studies are recommended for all obese children, not just those with Prader-Willi, Miller added.
Prader-Willi syndrome is caused by a rare chromosomal defect and occurs in only one of every 12,000 to 15,000 people, according to the Prader-Willi Syndrome Association. Children and adults with the disease have mental impairment, poor muscle tone and appetites so insatiable their parents often have to lock up food. Many patients become morbidly obese.
Overall, about 9 million children in the United States are overweight or obese. That's about three times as many as in 1980, and the causes vary, according to the Centers for Disease Control and Prevention.
" Prader-Willi syndrome highlights the major problem of obesity - it's more than just overeating," said Bryan E. Hainline, at the Indiana University. " There are genes that control it and other physiological factors that impair health."
Obesity also can lead to severe respiratory problems as fat accumulates in the upper body and throat, and these effects cause the most problems for obese patients, including those with Prader-Willi, Hainline said. The UF study highlights this, he added.
Growth hormone was approved in the United States to treat Prader-Willi in 2000, but several children with the disease died after beginning the treatments. All died in their sleep and had been battling infections. To understand the problem, UF researchers decided to study how growth hormone affected sleep, monitoring patients on the therapy closely and performing sleep studies before and during treatment, Miller said.
The researchers studied 25 children and adults with Prader-Willi syndrome, a large sample for such a rare disorder. Four school-age children had increased difficulty breathing at night shortly after the treatment began. All began having problems after they were exposed to upper respiratory infections in school, the findings show.
The children's muscles were so weak at the beginning of the treatment they couldn't breathe with a stuffed-up nose, Miller said. Growth hormone worsened the problem, causing the tonsils to swell and exacerbating their sleep apnea.
Some children could also need to have their tonsils removed if necessary. This helps, but because of their poor muscle tone and obesity, Prader-Willi patients have more risks to anesthesia, Miller said.
