Statins and prostate cancer Endocrine Today, NJ - Nov 12, 2008 If that occurs, that would be another mechanism where statins could lower PSA and prostate cancer risk. Several other studies have investigated the effects ...
Drugs you can't have Stuff.co.nz, New Zealand - Nov 30, 2008 Here are a few of the good news stories: * Statins for heart disease: Around 300000 New Zealanders are now using cheap and effective anti- cholesterol drugs ...
High blood pressure during pregnancy Globe and Mail, Canada - Nov 7, 2008 But it's equally possible statins are producing misleading readings that could get in the way of an accurate diagnosis of cancer. ...
More good news about statins Drug Topics Magazine, NJ - Nov 14, 2008 The caveats: The effect of statins on the risk of prostate cancer was not determined in this study, and it is possible that lowered PSA levels resulting ...
Statins may disguise prostate cancer Healthcare Republic - Nov 6, 2008 'With lower PSA levels, physicians may be less likely to perceive patients to be at risk of prostate cancer and thus less likely to recommend a prostate ...
Recent News and Articles on the Keywords: cancer risk + risk + cancer Related to the article below (Last Update: 8/7/2008)
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Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study. - JM Chan, MJ Stampfer, E Giovannucci, PH Gann, J Ma … - The Journal of Urology, 1998 - jurology.com ... Plasma Insulin-Like Growth Factor-I and Prostate CancerRisk: A Prospective
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A meta-analysis of previous studies has shown that the statins, cholesterol-lowering medications, do not appear to reduce the incidence of cancer or cancer deaths.
Other studies have suggested that statins reduce the risk of developing cancer.
" Statins have been studied in numerous large-scale, randomized, active- or placebo-controlled trials for primary and secondary prevention of coronary artery disease. In these trials, statins reduced the risk of a first myocardial infarction and overall mortality. With long-term follow-up and collection of cancer data in a majority of studies, insight into the risk of cancer among statin-naïve persons and statin users can be derived," the authors write.
C. Michael White, from the University of Connecticut and Hartford Hospital, and colleagues, conducted a search of the medical literature from 1966 through July 2005 to identify randomized controlled trials of statins.
They found 27 articles ( n = 86,936 participants ) that met their criteria for inclusion, reporting 26 randomized controlled trials of statins with data on either cancer incidence ( n = 20 studies ) or cancer death ( n = 22 studies ).
" In our current meta-analysis, statins did not reduce the incidence of cancer or cancer death," the authors report. " No reductions were noted for cancers of the breast, colon, gastrointestinal tract, prostate, respiratory tract, or melanoma when statins were used." The authors continue, "… the patients in our meta-analysis were primarily treated with simvastatin and pravastatin. As such, we evaluated pravastatin alone and simvastatin alone on cancer incidence and death and found no impact."
" Statins have a neutral effect on cancer and cancer death risks in randomized controlled trials," the authors write in conclusion. " We could find no type of cancer that statins benefited or subtype of statin that reduced the risk of cancer.