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Recent News and Articles on the Keywords: vorinostat + patients + cutaneous  Related to the article below (Last Update: 12/1/2008)

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Recent News and Articles on the Keywords: 0.37 + web + 6,560  Related to the article below (Last Update: 8/7/2008)

VeriSign Reports Second Quarter 2008 Results
CNNMoney.com -
A listen-only live web cast and accompanying slide presentation of the earnings conference call will also be available at http://investor.verisign.com. ...
Web.com Reports Second Quarter 2008 Financial Results istockAnalyst.com
all 454 news articles »  VRSN

FLEXNEWS
Lydall Announces Financial Results for the Second Quarter and Six ...
CNNMoney.com - Aug 4, 2008
The call may be accessed in a listen-only mode at 877-440-5804 and will be webcast live on the Company's web site www.lydall.com under the Investor ...
Amkor Reports Second Quarter 2008 Results MarketWatch
Henry Schein Reports Record Second Quarter Results Trading Markets (press release)
Altra Holdings Announces Record Financial Results for the Second ... MarketWatch
all 498 news articles »  AMKR - LDL - AIMC
j2 Global Reports Q2 2008 Results Revenues of $60.7 million; EPS ...
MarketWatch - Aug 5, 2008
The Company offers faxing and voicemail solutions, document management solutions, Web-initiated conference calling, and unified-messaging and communications ...JCOM - WAR:CFL
AtriCure Reports Record Second Quarter 2008 Financial Results
PR Newswire (press release), NY - Aug 5, 2008
A live web cast of the conference call will be available online from the investor relations page of AtriCure's corporate web site at http://www.atricure.com ...ATRC

EFYTimes (press release)
Cuil The Conquerer: No Way!
EFYTimes (press release), India - Jul 28, 2008
(0.37 seconds) . This gives an idea of how much comprehensive the search is as of now. Now coming to the content, when we searched for EFYTimes, ...
Ashford Hospitality Trust Reports Second Quarter Results
MarketWatch -
Additional information can be found on the Company's web site at www.ahtreit.com. Certain statements and assumptions in this press release contain or are ...AHT
ALLETE Reports Second Quarter Earnings and Reaffirms 2008 Earnings ...
MarketWatch - Aug 1, 2008
More information about the company is available on ALLETE's Web site at www.allete.com. The statements contained in this release and statements that ALLETE ...ALE
Caribou Coffee Reports Second Quarter 2008 Results
Trading Markets (press release), CA - Aug 5, 2008
For more information, visit the Caribou Coffee web site at www.cariboucoffee.com . Certain statements in this release, and other written or oral statements ...CBOU
Manhattan Associates Reports Second Quarter 2008 Revenue and Earnings
FOXBusiness - Jul 23, 2008
Manhattan Associates will make its earnings release and published expectations available on its Web site (www.manh.com). Beginning September 15, 2008, ...MANH - OTC:CMTX
Littelfuse Reports Second Quarter Results
MarketWatch - Jul 30, 2008
The call will be broadcast live over the Internet and can be accessed through the company's Web site: www.littelfuse.com. Listeners should go to the Web ...LFUS
Source: Google News

Evolution of Dust Shells and Jets in the Inner Coma of Comet C/1995 O1 (Hale?Bopp) -
O LARDI?RE, S GARRO, JC MERLIN - Earth, Moon, and Planets, 1997 - Springer
... 6560) and processed by the RSD algorithm. ... expansion velocity of the dust shells is
about 0.37 km/s ... the expansion of shells are available on our web site: http ...

[PDF] Radiation-driven winds of hot luminous stars. XV. Constraints on the mass-luminosity relation of … -
AWA Pauldrach, TL Hoffmann, RH Mendez - Arxiv preprint astro-ph/0307040, 2003 - arxiv.org
... from the INES Archive Data Server on the Web at http ... was f/4, giving a pixel size
of 0.37 arc sec ... 650 ? in wavelength, with central wavelengths of 6560 ? and ...
-

From the Cover: Breed distribution and history of canine mdr1-1 {Delta}, a pharmacogenetic mutation … -
MW Neff, KR Robertson, AK Wong, N Safra, KW Broman … - Proceedings of the National Academy of Sciences, 2004 - National Acad Sciences
... their current relative frequencies (0.63 and 0.37, respectively ... supporting information
on the PNAS web site ... (2002) Biochemistry 41, 6548?6560.[CrossRef][Medline ...

Homograft and SVC Syndrome -
JR Oyarzun, JR McCormick - The Annals of Thoracic Surgery, 1998 - Soc Thorac Surgeons
... located on the World Wide Web at: The ... of Surgery Baylor College of Medicine 6560
Fannin St ... and 3 iatrogenic tracheobronchial lacerations (0.37%) were diagnosed ...

[PDF] Common and Distinct Patterns of Affective Response in Dimensions of Anxiety and Depression -
CL Larson, JB Nitschke, RJ Davidson - Emotion, 2007 - psyphz.psych.wisc.edu
... 3140, 3150, 3168, 3170, 3266, 3350, 3400, 3500, 3530, 6212, 6230, 6260, 3212, 6313,
6350, 6360, 6510, 6560, 6570, 9040 ... Men 2.22 a 0.38 4.98 b 0.37 7.41 c 0.32 ...

in the Galactic thin and thick disks?,?? -
T Bensby, S Feltzing, I Lundstr?m, I Ilyin - A&A, 2005 - edpsciences.org
... we have used the UVES solar spec- trum that is available on the web: www.eso.org ...
10306 13555 646 F5V 5.23 33.19 0.85 -0.17 6560 4.04 1.75 1.48 -0.07 SOFIN ...

PER KI N
E Beer, J Daub, C Palivan, G Gescheidt - J. Chem. Soc., Perkin Trans. 2, 2002 - rsc.org
... Accepted 18th June 2002 First published as an Advance Article on the web 17th July ...
Structure of the doublet-state radical ions The hfcs of 0.35 and 0.37 mT in ...
-

S100? correlates with neurologic complications after aortic operation using circulatory arrest -
SA LeMaire, JK Bhama, ZC Schmittling, PJ … - The Annals of Thoracic Surgery, 2001 - Soc Thorac Surgeons
... full/71/6/1913 on the World Wide Web at: The ... Address reprint requests to Dr Coselli,
6560 Fannin, #1100, Houston ... & hemiarch 24 (65%) 24 (100%) 0 (0%) 0.37 21 (88 ...

Empirical Modelling of Genetic Algorithms -
R Myers, ER Hancock - Evolutionary Computation, 2001 - MIT Press
Page 1. Empirical Modelling of Genetic Algorithms Richard Myers
rich@cs.york.ac.uk Department of Computer Science, University of ...

Nanostructural control of cup-stacked carbon nanotubes with 1-benzyl-1, 4-dihydronicotinamide dimer … -
K Saito, M Ohtani, S Fukuzumi - Chemical Communications, 2007 - rsc.org
... First published on the web 15th November 2006. ... Chem. Soc., 2006, 128, 6560 [Links]. ...
Calcd for C 577 (C 12 H 13 N 2 O)?26(H 2 O): C, 93.06; H, 0.89; N, 0.37. ...
-

Source: Google Scholar
 
 

Vorinostat in patients with advanced, refractory cutaneous T-cell lymphoma

A pivotal Phase IIb open-label study evaluated Vorinostat ( Zolinza ) in patients with advanced, refractory cutaneous T-cell lymphoma ( CTCL ).

In the study, 30 percent of the patients ( 22 of 74 ) responded to treatment with Vorinostat as measured by the objective response rate.

The single-arm, non-randomized study included 74 patients with advanced disease who had previously failed a median of three systemic therapies.
Patients were given 400 mg once daily until disease progression or intolerable toxicity, with modifications to the dose, as needed, to either 300 mg once daily or 300 mg once daily for five days per week.

Secondary endpoints from the study included the following: duration of response, time to progression, time to response, and relief from pruritus.
Median response duration for all patients: this endpoint was not reached because the majority of patients continued to respond, but was estimated to be at least four months ( 118 days )
Median time to progression in patients who responded to treatment: this endpoint was not reached but was estimated to be at least five months ( 148 days ).
In addition, the median time to response was less than two months ( 55 days ).
Vorinostat also reduced pruritus in nearly 32 percent ( 23 of 72 ) of study participants.

The most common side effects observed in the study were diarrhea ( 49 percent ), fatigue ( 46 percent ), nausea ( 43 percent ), anorexia ( 26 percent ), dysgeusia ( 24 percent ) and thrombocytopenia ( 20 percent ).

Vorinostat, also known as suberoylanilide hydroxamic acid ( SAHA ), belongs to a new class of targeted anticancer agents called histone deacetylase ( HDAC ) inhibitors.
Histone deacetylation is thought to be a mechanism for silencing some tumor suppressor genes and other genes responsible for cell cycle progression, cell proliferation, programmed cell death ( apoptosis ), and differentiation.

Source: 2006 American Society of Clinical Oncology ( ASCO ) – Annual Meeting

 
 
 
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