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Recent News and Articles on the Keywords: cancer + skin + lapatinib  Related to the article below (Last Update: 12/1/2008)

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Recent News and Articles on the Keywords: cancer + 384 + 0.23  Related to the article below (Last Update: 8/7/2008)

Faces & Places
Jasper Newsboy,  USA - Aug 5, 2008
... District's breast and cervical cancer control program offers eligible women free breast exams, mammography and pap smears. Call Jasper - 384-6829; ...
Community Calendar
The Argus, CA -
Fundraiser? Noon to 5 pm Leukemia and Lymphoma Society Team in Training fundraising festival at Seven Hills Park, 384 Florence St., Union City. ...
Community Calendar
The Argus, CA - Aug 6, 2008
Fundraiser? Noon to 5 pm Leukemia and Lymphoma Society Team in Training fundraising festival at Seven Hills Park, 384 Florence St., Union City. ...
Wine/Food Events
Arizona Republic, AZ - Aug 5, 2008
520-384-2993. www.coronadovineyards.com. Super Tuscan Wine Tasting: 6:30 pm Aug. 24. Learn about and taste seven Tuscan wines, which are paired with food. ...
West Roxbury and Roslindale community notes
Wicked Local West Roxbury, MA -
For information call Nancy Sableski, manager of children?s education, at 617-384-5239 by Aug. 15 for fall training. ...
At Your Service
Times Colonist, Canada - Aug 3, 2008
250-384-9934 or www.citizenscounselling.com NEED Crisis and Information Line is available 24 hours a day, every day of the year, to listen and provide ...
NCI Assay Screens BRCA2 Mutations in Mouse ESCs
Cell Based Assay News (subscription), NY - Aug 1, 2008
Are you planning to develop this assay to be done in higher throughput, such as 384- or 1536-well plates? At present we are able to do, as I said, ...
Pink raises breast cancer awareness
Victoria News,  Canada - Jul 31, 2008
For questions about breast cancer or information about the CIBC Run for the Cure, please visit online at www.cbcf.org or call 250-384-3328.
Cancer laboratory robot works inside
Laboratory Talk, UK - Jul 21, 2008
The Portsmouth team will use the robot to test potential anti-cancer drugs against human tumour-derived cells in 96 and 384 well plates. ...
Community Calendar
The Argus, CA - Aug 4, 2008
Fundraiser? Noon to 5 pm Leukemia and Lymphoma Society Team in Training fundraising festival at Seven Hills Park, 384 Florence St., Union City. ...
Source: Google News

Consumption of fermented milk products and breast cancer: a case-control study in The Netherlands -
HS Gill - Cancer Research, 1989 - AACR
... none was 0.50 (95% confidence interval, 0.23-1.08 ... and dairy food consumption and
breast cancer: a pooled ... Health J. Nutr., February 1, 2000; 130(2): 384 - 384. ...

Preventive effects of drinking green tea on cancer and cardiovascular disease: Epidemiological … -
K Nakachi - BioFactors, 2000 - IOS Press
... nine-year follow-up study (384 cancer cases) [5 ... significantly exertedits
preventiveeffects on lung cancer in both ... 0.53 (0.17?1.57) and 0.69 (0.23? 1.88) for ...

Cancer-Preventive Effects of Drinking Green Tea among a Japanese Population -
K Imai, K Suga, K Nakachi - Preventive Medicine, 1997 - Elsevier
... cancer onset among a total of 384 cancer patients showed ... TABLE 3 Relative Risk of
Cancer Incidence by Green ... 1.0 1.20 (0.68?2.09) 0.53 (0.23?1.23) Females ...

[CITATION] A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer -
S Paik, S Shak, G Tang, C Kim, J Baker, M Cronin, … - New England Journal of Medicine, 2004 - Mass Med Soc
... quantitative TaqMan RT-PCR reactions in 384-well plates ... multigene assay to predict
recurrence of breast cancer ... 0.48?1.05) Clinical tumor size 0.23 1.26 (0.86 ...

Sulfotransferase 1A1 (SULT1A1) polymorphism and bladder cancer risk: a case-control study -
L Zheng, Y Wang, MB Schabath, HB Grossman, X Wu - Cancer Letters, 2003 - Elsevier
... determined the SULT1A1 Arg213His genotypes in 384 incident bladder ... significant reduced
risk of bladder cancer only in women (OR=0.42; 95% CI 0.23?0.78) and ...

Hormone replacement therapy, reproductive history, and colon cancer: a multicenter, case-control … -
E Kampman, JD Potter, ML Slattery, BJ Caan, S … - Cancer Causes and Control, 1997 - Springer
... HRT use tend to be associated more obviously inversely with colon cancer risk among ...
of these with family history were, respectively, 0.11 and 0.23 ? see also ...

Contralateral Breast Cancer in BRCA1 and BRCA2 Mutation Carriers -
K Metcalfe, HT Lynch, P Ghadirian, N Tung, I … - Journal of Clinical Oncology, 2004 - jco.ascopubs.org
... was 9.1% for 171 women who received radiotherapy, and was 33.8% for 17 women who
did not receive radiotherapy (HR, 0.23; P = .01 ... Br J Cancer 83:384-386, 2000 ...

[PDF] Breast Cancer Risk and Fatty Acids in the Breast and Abdominal Adipose Tissues -
JA Petrek, LC Hudgins, B Levine, MN Ho, J Hirsch - jnci, 1994 - jnci.oxfordjournals.org
... cancer J Natl Cancer Inst 85:384-388, 1993 ... patients per year would develop breast
cancer) according to ... 0.85 ? 0.23 (0.00-1.74) 0.03 ? 0.05 (0.00-0.27) 0.19 ...
-

… compared neoadjuvant chemoradiation and surgery to surgery alone for resectable esophageal cancer -
JD Urschel, H Vasan - The American Journal of Surgery, 2003 - Elsevier
... cancer recurrences (OR 0.38, 95% CI 0.23 to 0.63 ... Record in Scopus | Cited By in Scopus
(384). ... chemoradiation for squamous cell esophageal cancer: a prospective ...

Nutrient intake and cancer of the pancreas: a case-control study in Athens, Greece -
V Kalapothaki, A Tzonou, C Hsieh, A Karakatsani, A … - Cancer Causes and Control, 1993 - Springer
... 384 Cancer Causes and Control. ... odds ratios (OR) and 95% confidence intervals (CI)
for cancer of the pan ... Crude fiber 0.88 (0.72-1.08) 0.23 0.70 (0.54-0.90) 0.005 ...

Source: Google Scholar
 
 

Liver cancer: skin rash in patients treated with Lapatinib linked to response to treatment

In a study of a new drug for liver cancer, researchers found that the development of a skin rash correlated directly with the patient's response to treatment.
Patients who developed a rash lived twice as long as those who did not.

The study included 57 patients with advanced liver, gallbladder and bile duct cancers who were not candidates for surgery and who received a new agent called Lapatinib that prevents two epidermal growth factors receptor ( EGFR ) pathways from becoming activated in cancer cells.

The EGFR pathway has been implicated in the growth and spread of many cancers.

When the researchers evaluated the toxic effects of treatment with Lapatinib, they found that twenty of the patients treated had developed a skin rash. Patients who developed the rash lived for an average of 10 months, compared to five months for those patients who did not develop a rash.

" While we don't yet know exactly why this has been reported here and in other studies, it has implications for predicting the growth of cancer and could be a method to identify patients with advanced cancer who would be most likely to respond to this treatment," said Ramesh K. Ramanathan, principal investigator of the study and at the University of Pittsburgh School of Medicine.

According to the study results, Lapatinib was well-tolerated by the patients.
Two of the patients with primary liver cancer in the study had a partial response to treatment and the disease was stabilized in an additional 17 patients.

Source: University of Pittsburgh Medical Center, 2006

 
 
 
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