Advances in Treating Depression OR-Live, CT - So there is often a reason to combine antidepressants." Clinicians will look to combine medications if the patient with depression has tolerated the initial ...
Zapping depression Philadelphia Inquirer, PA - Neuronetics didn't seek approval to treat all major depression; when antidepressants work well, they are hard to beat. Still, the FDA rejected the initial ... Types of Brain StimulationPhiladelphia Inquirer all 2 news articles »
Treating depression seen important in heart failure Canada.com, Canada - The authors prospectively collected data on depression status and use of antidepressants. Roughly 16 percent of the study subjects were taking some form of ...
Serotonin Enhancing Pharmaceuticals OpEdNews, PA - Several decades ago, less than 1 percent of the US population were diagnosed with depression, some have said. Today, it is believed that about 10 percent of ...
Drug interactions can lead to adverse reactions Villages Daily Sun, FL - Depending on the combination, adverse reactions can include depression, bleeding, confusion, constipation, urine retention and dangerously low blood ...
Light Therapy for the Low-Light Months Examiner.com - 48 minutes ago It should be noted that the Food and Drug Administration has not approved Light Therapy as any official form of antidepressant. ...
2008 in Review Am J Psychiatry (subscription) - 9 minutes ago Perhaps no area has garnered more attention recently in child psychiatry than antidepressant safety and efficacy. In 1997, Emslie and colleagues (6) were ...
Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene - A Caspi, K Sugden, TE Moffitt, A Taylor, IW Craig, … - Science, 2003 - sciencemag.org ... a browser that does not support current Web standards ... the predicted direction (b =
?0.89, SE = 0.37, t = 2.39 ... events on self-reports of depression symptoms was ...
Changes in depression and anxiety after resective surgery for epilepsy - O Devinsky, WB Barr, BG Vickrey, AT Berg, CW Bazil … - Neurology, 2005 - AAN Enterprises ... anxiety are provided in table E-1 on the Neurology Web site; go ... of depression and
anxiety and the laterality (left vs right; depression, 2 = 0.37, p = 0.544 ...
Social supports and serotonin transporter gene moderate depression in maltreated children - J Kaufman, BZ Yang, H Douglas-Palumberi, S … - Proceedings of the National Academy of Sciences, 2004 - National Acad Sciences ... In predicting children's depression scores, generalized estimating equations (GEE)
were used ... 5-HTTLPR allele frequency between the two groups ( 2 = 0.37, df = 2 ...
Depression in Medicaid-Covered Youth: Differences by Race and Ethnicity - LP Richardson, D DiGiuseppe, M Garrison, DA … - Archives of Pediatrics & Adolescent Medicine, 2003 - archpedi.highwire.org ... because your Web browser does not support basic Web standards ... and black (OR, 0.31;
95% CI, 0.26-0.37) youth were less likely to have a depression diagnosis ... -
Comparison of six depression rating scales in geriatric stroke patients - B Agrell, O Dehlin - Stroke, 1989 - Am Heart Assoc ... http://stroke.ahajournals.org located on the World Wide Web at: The ... TABLE 2. External
and Concurrent Validity of Six Depression Rating Scales ... 0.77 0.86 0.37f ...
Cognitive Therapy vs Medications in the Treatment of Moderate to Severe Depression - RJ DeRubeis, SD Hollon, JD Amsterdam, RC Shelton, … - Archives of General Psychiatry, 2005 - Am Med Assoc ...Web browser does not support basic Web standards ... 1,173 = 1.67, P = .2, effect size = 0.37), whereas at ... Figure 3. Biweekly Hamilton Depression Rating Scale (HDRS ...
Antidepressants may do more than improve the symptoms of depression. According to a new study, these drugs may actually protect the brain in individuals who have repeated bouts of major depression.
Previously, investigators have reported that the size of the hippocampus, the brain area involved in learning and memory, is smaller in people who have experienced depression. This may be why patients with depression have trouble concentrating and paying attention, Dr. Yvette I. Sheline told.
Sheline, of the Washington University School of Medicine in St. Louis, and her colleagues speculated that the length of time a person is treated with antidepressants may affect the loss of hippocampal volume.
To investigate, the researchers interviewed 38 women with a history of depression. They used magnetic resonance imaging (MRI) to compare the size of the hippocampus in the depressed women with those of women who had never been depressed.
On average, the hippocampus was 10% smaller in the depressed subjects.
However, when they looked at the effect of antidepressants, they found that the hippocampus had not shrunk as much in patients who had been on antidepressants for a longer period of time.
Some of the subjects had never gone into full remission from their depression, Sheline told Reuters Health. But even among these subjects, she said, "there does seem to be a protective effect." Psychiatrists now recommend that patients who have multiple episodes of depression remain on antidepressants for the rest of their life, because they are less likely to relapse, Sheline noted. However, many patients don’t want to take antidepressants or don’t want to stay on them long enough. Her group’s findings suggest that, not only do patients feel better when taking the drugs, their physical brain is actually better off.
A lot of previous research in animals has shown that antidepressants do not harm the brain or the neurons, but that instead, there is a clear-cut benefit, Sheline noted. Her team’s study now shows the same is true for humans.
Her group now plans to invite the same women back for repeat MRI, in hopes of determining if the hippocampus shrinks more as time goes by, and if antidepressants "improve the situation."
