Are Vitamins Helpful, Ineffective, or Harmful? findingDulcinea, New York - Nov 25, 2008 Although vitamins such as B12 supplements for the elderly and folic acid for women, and calcium and vitamin D for women over 65 have been proven to be ...
B Vitamins Reduce Alzheimer?s Risk Stop Aging Now, DC - Nov 19, 2008 The study found that high doses of folic acid, vitamin B6 and vitamin B12 did not slow the progression of Alzheimer?s disease symptoms in people with ...
Vitamin B 12 and Folate and the Risk of Anemia in Old Age The ... Archives of Internal Medicine - Nov 10, 2008 Background Screening for deficiencies in vitamin B 12 and folate is advocated to prevent anemia in very elderly individuals. However, the effects of vitamin...
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Vitamin pill may beat blues in elderly The West Australian, Australia - Nov 28, 2008 A study of 3700 men has found that high levels of homocysteine increased the risk of depression in people over 70 by interfering with the ?happy? brain ...
News Keeps Getting Worse for Vitamins New York Times Blogs, NY - Nov 20, 2008 That said, some extra vitamins have proven benefits, such as vitamin B12 supplements for the elderly and folic acid for women of child-bearing age. ...
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Recent News and Articles on the Keywords: folate + 8,820 + web Related to the article below (Last Update: 8/7/2008)
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Dietary supplements of folate and vitamin B12 can reduce the risk of hip fracture in elderly patients following a stroke, according to a new Japanese study.
The risk of hip fracture is significantly higher in stroke patients than in other individuals of the same age, and is thought to be associated with increased blood levels of a substance called homocysteine, Dr. Yoshihiro Sato and others note in this week’s Journal of the American Medical Association. Because folate and mecobalamin (vitamin B12) reduce homocysteine levels, the team thought that supplements of these nutrients could reduce fracture risk. Sato, at Mitate Hospital in Tagawa, and colleagues studied 628 patients aged 65 years or more who had residual paralysis on one side of the body a year or more after having a stroke. The participants were randomly assigned to take folate and mecobalamin daily, or inactive placebos.
During 2 years of follow-up, the number of falls in each group was virtually the same, but there were only six hip fractures in the supplement group compared with 27 in the placebo group.
Even though homocysteine levels dropped in the active treatment group and rose in the placebo group, bone mineral density did not differ significantly between groups -- so that didn’t explain the fewer number of fractures. As two editorialists point out, although the results support a link between homocysteine levels and fracture risk, "final proof of causality will have to come from elucidation of the biological mechanism underlying this relationship."
Also, Sato’s group cautions that while they found folate and mecobalamin treatment to be associated with striking decreases in fracture risk, "generalization to broader non-Japanese populations should be performed with caution."