Health calendar Monroe News Star, LA - Parkinson's Disease Support Group ? 11 am second Monday of the month, St. Alban's Episcopal Church, 2816 Deborah Drive, Monroe. ...
Tech trio survives rare disease, readies for state showdown Macon Telegraph, GA - Nov 27, 2008 Diagnosed the year before with a heart condition known as Wolff-Parkinson-White syndrome, the 24-year-old?s heart ? for the first time in his life ? began ...
Art from the heart Helena Independent Record, MT - The 12-year-old twin brothers recently lost their mother to Parkinson?s Disease. Sylvia Michaelson spent more than 12 hours shopping on Black Friday, ...
Boynton Beach vet's life a battle since Gulf War Palm Beach Post, United States - Nov 30, 2008 It's no news to Pintos, a Marine master sergeant from Boynton Beach who suffers from Parkinson's disease and other muscular and intestinal ailments, ...
New Longevity Drugs Poised to Tackle Diseases of Aging ABC News - Nov 25, 2008 By BRANDOM KEIM Cancer, diabetes, Alzheimer's, Parkinson's, heart disease: All have stubbornly resisted billions of dollars of research conducted by the ...
The dark heart of a beloved hero The Australian, Australia - Nov 28, 2008 Do they endorse Dower's documentary, contributing to the evisceration of a beloved American hero who has Parkinson's disease? Or do they distance themselves ...
The greatest Philippine Star, Philippines - Perhaps partly as a result of all the punishment he took in the ring, Ali developed Parkinson?s disease after he retired in 1981. ...
After the Tears People Magazine - Nov 28, 2008 By Karen S. Schneider Michael J. Fox Faces An Uncharted Future with Courage and Compassion as He Confronts a Cruel Foe: Parkinson's Disease Michael J. Fox ...
Caregiver writes of hard, rewarding role WTOP, DC - Nov 30, 2008 ... Alzheimer's and Parkinson's disease. At 84, Kennedy herself has battled heart problems and osteoarthritis, but still does all the housework and cooking. ...
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Recent News and Articles on the Keywords: web + 0.14 Related to the article below (Last Update: 8/5/2008)
FelCor Reports Second Quarter Operating Results MarketWatch - 22 minutes ago Additional information can be found on the Company's Web site at www.felcor.com. We invite you to listen to our second quarter earnings Conference Call on ...FCH
How I Learned to Stop Worrying and Love Windows Vista. NOT! ZDNet - Aug 4, 2008 Granted, her older box used Firefox 2.0.0.14 and the new one 3.0, but when I regression tested 3.0 as the default browser on my own XP systems and with the ...
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Measuring the Independence of Central Banks and Its Effect on Policy Outcomes - A Cukierman, SB Web, B Neyapti - The World Bank Economic Review, 1992 - World Bank ... bank in- depen- dence" (index) 0.33 0.33 0.31 0.30 0.30 0.30 0.29 0.29 0.27 0.27
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classification ... MB MN MB MN MB MN 0 0.140.14 1 1 0.25 0.25 0.1 0.17 0.3 0.87 ...
Harvesting implicit group attitudes and beliefs from a demonstration web site - BA Nosek, MR Banaji, AG Greenwald - Group Dynamics: Theory, Research, and Practice, 2002 - content.apa.org ... 63 ms (d 0.28); conservative set: face 26 ms (d 0.12), name 29 ms (d 0.14). ... Explicit
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illustrate a need for high precision in Web IR algorithms ... 15 25 0.14 50 2 0.01 ...
[PDF]An Adaptive Agent for Web Exploration Based on Concept Hierarchies - S Parent, B Mobasher, S Lytinen - Proceedings of the 9th International Conference on Human …, 2001 - maya.cs.depaul.edu ... On the other hand, a user interested in searching the Web for specific medical ... music:
1.000 blue: 0.15 new: 0.14 artist: 0.13 jazz: 0.12 review: 0.12 band ...
[PDF]Phylogenetic constraints and adaptation explain food-web structure - MF Cattin, LF Bersier, C Banasek-Richter, R … - Nature, 2004 - unifr.ch ... by one order of magnitude?in the prediction of these standard food-web descriptors. ...
T 0.06 [0.04] 0.08 0.05 [0] 0.03 0.10 [0] 0.10 0.14 [0.28] 0.15 0.08 [0.38 ... -
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Parkinson’s Drug Linked to Heart Valve Damage
Heart valve disease appears to be relatively common in Parkinson’s disease patients treated with pergolide (Permax), according to results of a new study. Evidence suggests that the degree of damage correlates with lifetime dose of the drug, but the effects may be reversible.
Pergolide belongs to a class of drugs called dopamine agonists. It is derived from ergot, a substance obtained from plants, and works by acting in place of dopamine, a natural substance in the brain needed to control movement.
Several cases of valvular heart disease associated with pergolide treatment have been reported recently, but the prevalence of the condition is unknown, Dr. D. G. Baseman of the University of Texas Southwestern Medical School, Dallas, and colleagues report in journal Neurology.
Using the clinical database of the Clinical Center for Movement Disorders at their institution, the investigators identified 82 patients who were confirmed to be currently taking the drug.
Forty-six of these patients underwent cardiac evaluation, and scores for heart valve regurgitation, or backward flow of blood, were compared with those from a comparison (control) group of patients of the same age participating in the Framingham Heart Study. Baseman’s team observed some degree of valvular regurgitation in 89 percent of the patients. The risk of abnormal valves was up to three times that observed in the control group, and there was an estimated 14-fold increased risk of regurgitation of heart’s the tricuspid valve. Valve scores increased with increased duration of pergolide use, the authors note.
In three patients with disabling heart disease, cessation of the drug was followed by improvements on cardiac tests.
"We believe that dopamine agonist therapy should be initiated with a nonergot drug," Baseman’s group concludes. "In those currently taking pergolide, consideration should be given to switching to a nonergot agonist until the safety of pergolide can be firmly established."
