A kid who flies past obstacles Sacramento Bee, USA - Nov 30, 2008 Born with a hole in his heart as a result of a rare congenital condition called tetralogy of Fallot, Todd underwent six surgeries by age 5, ...
Death of Hernando student touches many Tampabay.com, FL - Eric was born with a rare and complex congenital heart defect known as tetralogy of Fallot. The condition is composed of four specific defects that prevent ...
Young girl gives thanks for chance to be normal Joplin Globe, MO - Nov 26, 2008 Specialists in St. Louis later diagnosed the problem as tetralogy of Fallot with absence of pulmonic valve. Elise did not have Down syndrome, ...
Five-month-old among six kids to get open-heart surgery Jamaica Observer, Jamaica - Nov 10, 2008 He added: "One of the children had a special type of heart defect called tetralogy of fallot where not only was there a hole in the heart, ...
Lillian's family gives thanks every day Rockford Independent, MI - Nov 6, 2008 She was diagnosed with tetralogy of Fallot with pulmonary atresia, a congenital heart defect, as a baby. Lillian has had numerous surgeries and, on Nov. ...
Group puts its heart into giving kids a Gift of Life NJ.com, NJ - Nov 23, 2008 Wilson, now 13, was born with tetralogy of Fallot, a congenital heart defect that prevented blood from reaching his lungs. The syndrome is sometimes called ...
Topic: Congenital Heart Disease Cardiosource, DC - Nov 7, 2008 Patients with tetralogy of Fallot (TOF) should have regular follow-up with a cardiologist with expertise in ACHD. Postoperative issues include residual ...
'We were meant to have this dog' Chicago Sun-Times, United States - Nov 11, 2008 Kayla was born with a congenital heart defect called tetralogy of Fallot. She's had 29 heart surgeries, including an open-heart operation in June, ...
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Recent News and Articles on the Keywords: heart defect + heart + can Related to the article below (Last Update: 8/5/2008)
Clear picture of the heart Daily Commercial, FL - Lesmes is using a 3D transesophageal ecocardiogram probe the hospital bought this year to pinpoint Varros' heart defect. Hospitals across the nation are ...
Congenital heart disease: Disease of the innocent IBNLive.com, India - Aug 4, 2008 New Delhi: The Mehta couple is fighting for the right to terminate a pregnancy because the foetus is likely to be born with a congenital heart defect. ...
Taking cousin?s condition to heart, teens lend support Milwaukee Journal Sentinel, WI - Suzie Skalmoski, 12, was born with a heart defect that left her without a left ventricle. Matt and Danny McDonough, 17-year-old twin brothers from Whitefish ...
Amoxicillin: Drug Whys EMS1.com - Emergency Medical Service Resources, CA - The American Heart Association recommends prophylaxis with antibiotics for some dental procedures and a few highly invasive or surgical procedures (usually ...
Heart screening could save lives The Kingston Whig-Standard, Canada - Taylor, in fact, had confided to friends that she had bouts of dizziness and blackouts, classic symptoms of the deadly heart defect called arrhythmogenic ...
Genetic testing brings new hopes, hard choices Boston Globe, United States - Aug 3, 2008 A massive heart attack at age 44, they were told. In 2003, Downing's seemingly healthy brother, Gerard, the district attorney of Berkshire County, ...
Families put heart into horse event Norfolk Eastern Daily Press, UK - Just days after little Olivia Chapman was born to Norwich mum Tanya in an emergency Caesarean operation, it emerged the baby had a series of heart defects...
Fund set up for ailing tot Independent and Free Press, Canada - Abby Knight, born April 16, does not have a right ventricle in her heart, and has been in hospital for the past month undergoing heart surgeries and ...
Congenital Heart Disease Caused by Mutations in the Transcription Factor NKX2-5 - JJ Schott, DW Benson, CT Basson, W Pease, GM … - Science, 1998 - sciencemag.org ... of our site the best it can be. ... IV-4 (family MBF), whose defect spontaneously closed.
Other structural heart malformations identified in affected individuals ...
Congenital Heart Defects Natural Course and In Utero Development - S Yagel, A Weissman, Z Rotstein, M Manor, J Hegesh … - Circulation, 1997 - Am Heart Assoc ... Conclusions Our study presents novel data and information regarding the in utero
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Spatio-temporal image correlation(STIC): new technology for evaluation of the fetal heart - GR DeVore, P Falkensammer, MS Sklansky, LD Platt - Ultrasound in Obstetrics and Gynecology, 2003 - doi.wiley.com ... concepts and techniques described here can be adequately used by more sonographers
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Pregnancy Risky for Women with Heart Defect
Women with a congenital heart defect called tetralogy of Fallot can have successful pregnancies, but overall they have an increased risk for miscarriage and their offspring are at increased risk for birth defects, results of a study indicate.
In tetralogy of Fallot, major arteries are misconnected to the wrong chambers of the heart. The anomaly is usually corrected surgically in childhood.
"Although successful pregnancy has been documented in small series, data are incomplete for maternal and fetal outcomes in women with tetralogy of Fallot," Dr. Gruschen R. Veldtman and colleagues from the Mayo Clinic in Rochester, Minnesota note in the Journal of the American College of Cardiology.
In a review of data on 72 women with tetralogy of Fallot, the researchers found that 43 of the women had a total of 112 pregnancies and 82 of these pregnancies were successful. In eight women, tetralogy of Fallot remained unrepaired at the time of their successful pregnancies.
Adverse events for the mother were rare, but when they occurred they were often heart-related, the team reports. This was the case in five of the six women who experienced adverse events.
Unrepaired tetralogy of Fallot and abnormalities in the pulmonary artery were linked with low infant birth weight.
While premature delivery affected just 1 percent of women, 8.5 percent of infants were small for their gestational age; six out of the seven low-birthweight infants were born to women with unrepaired tetralogy of Fallot.
According to the medical records, the rate of spontaneous fetal loss was 24 percent, which is substantially higher than the national average of 10 percent, the team notes.
Birth defects, including congenital heart disease and stomach outlet obstruction, occurred in 6 percent of the infants, a rate double that seen in the general population.
In the journal, Dr. John S. Child comments that the findings are "reassuring in that women with well-repaired tetralogy of Fallot ... appear at an overall low risk of morbidity from pregnancy."
However, the editorialist from the Ahmanson-UCLA Adult Congenital Heart Disease Center in Los Angeles, adds that the relatively high rates of successful pregnancy plus the increased odds of birth defects in the children means that "the number of tetralogy of Fallot patients will steadily increase with each coming year."
