Tried and tested Journal Live, UK - Nov 29, 2008 The mum-of-four feels so strongly about growing old gracefully that Serenity is running a Better than Botox campaign. ?The trend for Botox among 30 to ...
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Recent News and Articles on the Keywords: aging + skin + botox Related to the article below (Last Update: 8/5/2008)
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Source: Google Scholar
Botox: Not Just a Boon for Aging Skin
Most people have heard of it as an answer to forehead wrinkles and crow’s feet, but since its approval in 1989 for the treatment of certain eye disorders, Botox has made itself useful in multiple therapeutic areas. New research reported in the August 8 issue of the New England Journal of Medicine now confirms that Botox is also an effective treatment for post-stroke spasticity. Spasticity causes muscles in the arms or legs to tighten uncontrollably, and can lead to pain, discomfort, and disability. The condition is not uncommon in people who have suffered brain injury associated with stroke, and for those who have spasticity in the hands, tasks as simple as getting dressed or making meals can become nearly impossible to manage.
Although Botox has not received FDA approval for the treatment of spasticity, doctors have used it to address post-stroke muscle problems for some time. The drug works by entering nerve endings around the muscle where it is injected, and blocking the release of chemical messages that cause the muscle to contract.
The two-year study, which involved nineteen medical institutions, is the first large trial to show that one-time injections of Botox can improve hand function and muscle tone in post-stroke spasticity.
"This is great news." says Dr. Cindy Ivanhoe, Director of the Brain Injury Program at the Texas Institute for Rehabilitation and Research. "It validates what those of us who treat many patients have known for years. The use of Botox in conjunction with appropriate therapies can enhance the quality of life and function for many patients."
The placebo-controlled study involved 126 patients with some measure of spasticity in the hands. Forty of the 64 participants who received the Botox reported improvement in the area where it was injected, and no adverse side effects were reported. In the group that received placebo, 17 of the 62 patients reported improvement.
"Perhaps now more physicians will refer patients for Botox injections and acknowledge the benefits of those injections." says Ivanhoe. "I hope this study will help convince people that Botox can significantly improve function in patients with spasticity after an injury to their brain."