How to prevent Alzheimer?s disease ? part 1 Food Consumer, IL - Nov 21, 2008 The results were presented for the first time at the world's largest dementia conference held in July 2008. Previous research has shown that an active ...
Submitting to the Science of Prevention Wall Street Journal - Nov 25, 2008 These are inflammation, immune function, the inefficient use of oxygen and the capacity to regenerate stem cells in the blood. While these are not specific ...
HIV/AIDS Canada.com, Canada - Nov 13, 2008 At this point the virus begins rapidly taking over immune cells in the blood. The symptoms of this phase are flu-like and include: When the symptoms begin ...
Health: Alzheimer?s disease & dementia The New Nation, Bangladesh - Nov 13, 2008 Alzheimer's destroys brain cells, causing problems with memory, thinking and behavior severe enough to affect work, lifelong hobbies or social life. ...
Stem cell research focus of meeting San Diego Union Tribune, United States - Nov 8, 2008 Science must overcome several issues, such as immune-system rejection of transplanted cells or the risk of the cells creating tumors, said Joseph Wu, ...
A Powerful, Beauty Enhancing Oil from Morocco Natural News.com, AZ - Nov 28, 2008 The antioxidants and essential fats make it a great brain food, preventing Alzheimer's and dementia. Couple formation of prostaglandins, some of which ...
MS patients donate brains to the Cleveland Clinic for valuable ... The Plain Dealer - cleveland.com, OH - Nov 25, 2008 Most study Alzheimer's disease and dementia. The Clinic's program is different from most others, said Bruce Trapp, program founder and chairman of the ...
Are Vaccinations Causing Early Alzheimer?s? American Chronicle, CA - Nov 23, 2008 Forgetting recently learned information is one of the most common early signs of dementia. A person begins to forget more often and is unable to recall the ...
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Recent News and Articles on the Keywords: key + 0.50 + immune Related to the article below (Last Update: 8/5/2008)
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Immune Cells Key to HIV-linked Dementia
September 23, 2005 08:41:15 PM PST
Macrophages, immune system cells that fight infection, may help cause the dementia seen in some patients with HIV, according to a new study.
Researchers at the University of Florida and the University of California, San Francisco, found that macrophages, in their attempts to attack HIV, may damage the brain's temporal lobe, where many memories are stored.
Because HIV mutates almost 100 times faster in the temporal lobe than in other parts of the brain, large numbers of macrophages migrate to this area to attack the virus, resulting in a potentially damaging inflammation.
"In a way, it's not the virus that causes the dementia," researcher Marco Salemi, a UF assistant professor of pathology and immunology, explained in a prepared statement. "It's the fact that there is this continuous migration of infected macrophages to the temporal lobe. The virus mutates much faster there, [so] the macrophages keep accumulating and keep creating this inflammation that leads to dementia."
About 15 percent of people with HIV will develop dementia as their disease progresses. This research may help scientists find ways to block the migration of macrophages to the brain and prevent HIV-associated dementia, Salemi said.
The study was published in the Journal of Virology.
