DHEC changes erode beach protection law The State, SC - Nov 20, 2008 Harris? worries are more immediate: Her daughter Ashley has asthma. Over eight months, reporters Sammy Fretwell and John Monk interviewed more than 200 ...
Exclusive: DHEC under fire The State, SC - Nov 15, 2008 Harris? worries are more immediate: Her daughter Ashley has asthma. The SC Department of Health and Environmental Control was formed in 1973 after several ...
SP says prospects are good for "best pipeline in history" Pharma Times, UK - Nov 25, 2008 Chief executive Fred Hassan said that ?our scientists have built a pipeline that we believe is the best in our history and one of the best in the industry?, ...
The surprising ways our climate can affect your health and how ... Southern Star, Ireland - Nov 13, 2008 We would all love to know the answer to asthma, but many sufferers find their condition worsens if there is a thunderstorm when pollen counts are high ? the ...
Flu season facts Chicago Daily Herald, IL - Nov 9, 2008 In most years, the new strains turn up first in Asia, and then spread around the world to the US That gives American scientists a chance to spot epidemic ...
Recent News and Articles on the Keywords: asthma + 250,000 + 0.29 Related to the article below (Last Update: 8/5/2008)
YorkTest Laboratories Reveal The UK's Top Ten Intolerant Foods ... Medical News Today (press release), UK - Symptoms such as irritable bowels, migraines, asthma and fatigue are synonymous with other conditions; they are often wrongly diagnosed and remain a real ...
Children?s Hospital to build in New Berlin Milwaukee Business Journal, WI - Aug 1, 2008 The clinic, to be named Children?s Hospital of Wisconsin Clinics-New Berlin, will include pediatric specialties such as allergy/asthma, audiology, ...
Olympics Notebook Winston-Salem Journal, NC - Jul 24, 2008 Asthma sufferers would be expected to encounter more problems if pollution in Beijing does not clear substantially. ■ The International Olympic Committee ...
Olymics notes Austin American-Statesman, TX - Jul 25, 2008 Clenbuterol is usually prescribed to those with breathing disorders, such as asthma, and also is well-known in horse racing circles as a treatment for ...
Ex-UNC midfielder makes US roster Charlotte Observer, NC - Jul 24, 2008 Clenbuterol is not approved for use in this country, but it is in some countries by prescription to help asthma patients breathe easier. ...
Master your mind New Straits Times, Malaysia - Jul 19, 2008 "This is how it brings about blood pressure, asthma and diabetes." Doctors today can treat the effects, but they do not address the root cause of the ...
North Canton to mark 100 years of Hoover sweepers Canton Repository (subscription), OH - Jul 18, 2008 Twenty years later, it sold more than 250000. Figures weren't available, but Clifford Wood, former vice president of the extinct Vacuum Cleaner ...
On the LAM Jewish Exponent, PA - Jul 17, 2008 ... lung and chest pain, they are frequently misdiagnosed with a host of other, more common diseases, like emphysema, chronic bronchitis or asthma. ...
Medical groups prep for physician networks Crain's Detroit Business, MI - Jul 14, 2008 The three groups represent 2000 independent physicians and 250000 managed care patients. ?There is a lot of variation in care between physicians,? said Dr. ...
Preparation and characterization of theophylline loaded chitosan/?-cyclodextrin microspheres - WF Zhang, XG Chen, PW Li, QZ He, HY Zhou - Journal of Materials Science: Materials in Medicine, 2008 - Springer ... due to its new effect on the treatment of asthma. ... of Food and Fermentation Industries,
Jinan 250000, PR China ... 0.23 8.26 ? 0.58 24 6.03 ? 0.29 13.20 ? 0.95 ... -
[CITATION] Fish Consumption and Risk of Sudden Cardiac Death MO Measure - JAMA, 1998 -
Intake assessment for benzoates in different subgroups of the Flemish population - M Bilau, C Matthys, C Vinkx, S De Henauw - Food and Chemical Toxicology, 2007 - Elsevier ... However, cases of urticaria, asthma, rhinitis or anaphylactic shock have ... from the
region of Ghent (?250000 inhabitants) in ... 1.0 (0.74), 2.4, 42, 0.3 (0.29), 0.9, 56 ...
[PDF]IMPACT AND DAMAGE COST ASSESSMENT METHODOLOGY - A METHODOLOGY - www-cenerg.ensmp.fr ... These include, for example, the number of asthma attacks, hospital visits or admissions
and mortality impacts, such as the number of Years Of Life Lost (YOLL ...
[PDF]Cost-Effectiveness Analysis of Face-to-face Smoking Cessation Interventions by Professionals - TL Feenstra, HH Hamberg-van Reenen, RT Hoogenveen, … - Institute for Medical Technology Assessment, 2003 - publishing.eur.nl ... Men Women Men Women Men Women Men Women Myocardial infarction 3.2 1.7 2.9 3.2 1.6
1.3 0.290.29 Coronary heart disease 3.1 2.2 2.9 3.2 1.6 1.3 0.290.29...
Source: Google Scholar
Scientists Spot Treatment Target for Severe Asthma
September 22, 2005 08:41:11 PM PST
Blocking a powerful immune system compound called tumor necrosis factor alpha (TNF alpha) may prove an effective way to treat severe asthma, according to a small study in the current issue of the journal Thorax.
About one in 10 people with asthma has a severe form of the disease, which correlates with relatively large amounts of circulating TNF alpha. TNF alpha is also found in a number of chronic inflammatory conditions such as rheumatoid arthritis, psoriasis and Crohn's disease.
The study, led by researchers at Southampton General Hospital in England, included 26 healthy people, 67 people with mild asthma and 51 people with severe asthma. Bronchial fluid and lung tissue samples showed that TNF alpha levels were much higher in the people with severe asthma and that the TNF was concentrated in mast cells, which are immune cells that play a role in the asthmatic inflammatory reaction.
For 12 weeks, 15 of the people with severe asthma received twice-weekly 25 mg. injections of the drug etanercept (brand name Enbrel), which blocks TNF alpha production. They continued to take their asthma medications. By the end of the study, these patients showed significant improvement in asthma symptoms and lung function, the researchers said.
Treatment with etanercept also curbed inflammatory reaction in the lungs and produced few side effects. While the findings suggest a potentially new method of treatment for severe asthma, further research is needed, the study authors said.
More information
The U.S. National Heart, Lung, and Blood Institute has more about asthma.
