Brain injury victims learn to cultivate new self-confidence Times Online, UK - The shame felt by Brian Cullinan at being unable to talk or write after suffering severe brain injuries became a corrosive force that threatened to destroy ...
Cognitive tests required for Europe-based troops Stars and Stripes, DC - Traumatic brain injury is a blow or jolt to the head or a penetrating head injury that disrupts the function of the brain. Severity ranges from mild ? a ...
Crashing to the bottom of the country MinnPost.com, MN - Motorcycle helmets, meanwhile, cut the risks of fatality in a crash by 37 percent and of brain injury by 67 percent, according to NHTSA. ...
Business awards Kentucky.com, KY - Edward D. Hall, director of the University of Kentucky Spinal Cord & Brain Injury Research Center, has been inducted into the National Spinal Cord Injury...
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Recent News and Articles on the Keywords: injury + brain + use Related to the article below (Last Update: 8/5/2008)
Wes Sears NASM CPT-CES, Jan Sears NASM CPT-CES Maui Weekly, Hawaii - Dr. John Medina, author of Brain Rules: 12 Principles for Surviving and Thriving at Work, Home, and School puts it this way: ?Driving while talking on a ...
Home for brain-injury survivors opens this month Lexington Minuteman, USA - Aug 4, 2008 ?Douglas House is the third residence built by SLI to help advance its mission to develop appropriate and affordable housing for survivors of brain injury,? ...
Coroner details massive injuries sustained by 3 students Urbana Daily Citizen, OH - "I use the word 'pulpification' when the brain no longer has its own structural integrity," Harshbarger said. Harshbarger said if the head trauma had not ...
WA biotech fund announces $5 million in grants Seattle Post Intelligencer - Eberhard Fetz, University of Washington, $1.07 million to develop and test electrical stimulators to help people recover from brain injury. ...
Posted -50 sec ago Chatham Daily News, Canada - Their use is also advocated by the Brain Injury Association of Chatham-Kent and the Chatham-Kent Children's Safety Village. disappointing that children ...
Chadron police give a shocking demonstration Chadron Record, NE - As part of the demonstration, Wallage explained that the taser uses a brief, high voltage electric shock to disconnect the brain and prevent the body from ...
Senators Press Pentagon On Health Care CBS News, NY - Aug 4, 2008 ... and eight other senators urged the Pentagon on Monday to expand health benefits to cover cognitive rehabilitation treatments for traumatic brain injury. ...
Bright and dark sides of nitric oxide in ischemic brain injury - C Iadecola - Trends in Neurosciences, 1997 - Elsevier ... and sepsis. We have recently begun to use iNOS knockouts to study the role
of iNOS expression in ischemic braininjury. The data ...
The Use of Hypertonic Saline in the Treatment of Traumatic Brain Injury. - JA Doyle, DP Davis, DB Hoyt - The Journal of Trauma: Injury, Infection, and Critical Care, 2001 - jtrauma.com ... The Use of Hypertonic Saline in the Treatment of Traumatic BrainInjury. Doyle,
Julie A. MD; Davis, Daniel P. MD; Hoyt, and David B. MD. ...
Traumatic Brain Injury in High School Athletes - JW Powell, KD Barber-Foss - JAMA, 1999 - Am Med Assoc ... article we use MTBI to describe injuries for which the injured player was removed
from participation and evaluated for a traumatic brain or head injury by the ...
THE INCIDENCE OF ACUTE BRAIN INJURY AND SERIOUS IMPAIRMENT IN A DEFINED POPULATION - JF KRAUS, MANN BLACK, N HESSOL, P LEY, W ROKAW, C … - American Journal of Epidemiology, 1984 - Oxford Univ Press ... Page 5. 190 KRAUSETAL. TABLE 1 Hospital admission indexing code numbers
and rubrics used for braininjury casefinding Rubric no. ...
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Study Casts Doubt on NSAID Use After Brain Injury
WEDNESDAY, July 26 (HealthDay News) -- Long-term use of the painkiller ibuprofen after brain injury led to a decline in cognitive abilities in rats, a new study found.
The findings may have implications for the treatment of patients with traumatic brain injury, because they are often prescribed ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) for chronic pain, said researchers from the University of Pennsylvania School of Medicine.
They published their findings online in the July issue of Experimental Neurology.
Previous human and animal research has shown that long-term use of ibuprofen for inflammation improves outcomes for Alzheimer's disease patients by reducing symptoms and delaying the onset of dementia.
This prompted the University of Pennsylvania team to investigate whether ibuprofen would improve long-term cognitive outcomes in brain-injured rats.
The study focused on two groups of rats. Over four months, one group received ibuprofen in their food. The doses were proportional to those given to humans. The other group of rats did not receive ibuprofen. Both groups were tested on their ability to find an underwater platform in a maze, a common test used to measure cognitive ability in animals.
To their surprise, the researchers found that the rats that were given ibuprofen performed far worse than the other rats.
"Although most untreated injured animals could find the platform, they were much slower to learn its location than non-injured animals. In contrast, almost none of the treated, injured animals could find the platform at all," study author Dr. Douglas H. Smith, director of the Center for Brain Injury and Repair, said in a prepared statement.
The findings suggest that the effects of long-term NSAID treatment after brain injury are not well understood.
"We have to remember that these are animal studies, and what we can take home is that we need further examination of potential negative effects in patients," Smith said.
More information
The American Academy of Neurology has more about brain injury
