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Recent News and Articles on the Keywords: metastatic cancer + metastasis gene + gene  Related to the article below (Last Update: 7/1/2008)

Metastatic susceptibility locus, an 8p hot-spot for tumour ...
7thSpace Interactive (press release), NY -
Both up and down-regulation of 8p21-22 gene expression was associated with metastasis. ADAMDEC1 mRNA and protein expression decreased during both ...
Identification Of 5 Genes Involved In The Metastasis Of Breast ...
Science Daily (press release) - Jun 20, 2008
This new discovery in the complex network that is the metastasis process of tumours provides key data on the knowledge of cancer and its spreading, ...

TopCancerNews.com
Possibility of suppressing cancer metastasis by eliminating mutant ...
TopCancerNews.com, TX - Jun 11, 2008
... degrades p53 can have the perverse effect of protecting mutated p53 and promoting metastasis. The p53 gene is inactivated in many types of cancer. ...
Cornerstone for development of new cancer treatments TopCancerNews.com
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Nanoparticles carry drugs into cells; new gene signature for ...
FierceBioResearcher, DC - Jun 3, 2008
... have identified a gene signature responsible for the spread of cancer from one organ to another, a process scientifically known as metastasis. ...
Researchers find gene signature profile for metastasis
News-Medical.net, Australia - Jun 2, 2008
... of the American Society of Clinical Oncology in Chicago, may represent a novel diagnostic tool in characterizing gene targets in metastatic cancer. ...
Intestinal Proteins May Be Effective Anti-Tumor Antigens
Science Daily (press release) - Jun 25, 2008
ScienceDaily (June 25, 2008) ? Mice immunized with an intestinal protein developed fewer lung and liver metastases following injection with colon cancer ...
Molecular-Genetic Imaging Based on Reporter Gene Expression
RedOrbit, TX - Jun 25, 2008
Noninvasive reporter imaging gene expression offers excellent opportunities to understand cancer progression, metastasis, and therapy in whole animals. ...
Noninvasive Imaging of Cell-Mediated Therapy for Treatment of Cancer RedOrbit
In Vivo Detection of Apoptosis RedOrbit
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We Need a New War on Cancer
U.S. News & World Report, DC - Jun 12, 2008
With unique markers on their surface and a set of different gene pathways, which are normally turned on in embryos but silent in mature cells, these cancer ...
Primary Tumors Fuel Growth of Cancer Cells Washington Post
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How Advanced Prostate Cancer Becomes Resistant To Androgen ...
Science Daily (press release) - Jun 1, 2008
In addition to measuring androgen levels in distant tumor sites, the researchers analyzed gene-expression patterns in the metastatic tissue to confirm the ...

The Money Times
Idle computer time can help contribute to global cancer fight
Sify, India - Jun 24, 2008
"Instead of studying one molecule or one gene, it is studying a host of problems in cancer. Cancer, as we know, is not a disease of a single gene or a ...
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Source: Google News

[CITATION] … IN PATIENTS WITH METASTATIC MELANOMA TREATED WITH AN ANTIGENIC PEPTIDE ENCODED BY GENE MAGE-3 AND … -
E Rankin, G Parmiani, F Arienti, Y Humblet, A … - Int. J. Cancer, 1999
... Accordingly, about 21% of the metastatic melanomas are ... Publication de l?Union
Internationale Contre le Cancer ... Patients with brain metastasis, as assessed by ...

Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer -
H Suzuki - Cancer Research, 1998 - AACR
... allele was found in all metastases in a ... occur frequently in lethal prostate cancer,
although a ... heterogeneity is found among different metastatic sites within ...

Survey of Gene Amplifications during Prostate Cancer Progression by High-Throughput Fluorescence in … -
L Bubendorf, J Kononen, P Koivisto, P Schraml, H … - Cancer Research, 1999 - AACR
... often found in the distant metastatic deposits sampled ... of MYC involvement in prostate
cancer metastases to pelvic ... the true prevalence of gene amplification in ...

Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis -
I Vlodavsky, Y Friedmann, M Elkin, H Aingorn, R … - Nature Medicine, 1999 - nature.com
... cDNA acquired a highly metastatic phenotype in ... Cloning of the heparanase gene enables
the ... for early detection and treatment of cancer metastasis and autoimmune ...

Drg-1 as a Differentiation-related, Putative Metastatic Suppressor Gene in Human Colon Cancer 1 -
RJ Guan, HL Ford, Y Fu, Y Li, LM Shaw, AB Pardee - Cancer Research, 2000 - AACR
... molecules, angiogenesis, and growth factors are involved in metastasis. Therefore,
understanding the gene expression changes in metastatic cancer cells may aid ...

… protein/Erk kinase 1 (MKK4/SEK1), a prostate cancer metastasis suppressor gene encoded by human … -
BA Yoshida, Z Dubauskas, MA Chekmareva, TR … - Cancer Res, 1999 - ncbi.nlm.nih.gov
... to the effect of a gene(s) at the metastatic site (MA Chekmareva et al., Cancer
Res., 58 ... kinase 1 (MKK4/SEK1) gene as a candidate metastasis suppressor gene ...

A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic -
Y Toh, SD Pencil, GL Nicolson - Journal of Biological Chemistry, 1994 - ASBMB
... the genes involved in breast cancer invasion and ... we analyzed a novel candidate
metastasis-associated gene ... 13762NF rat mammary adenocarcinoma metastatic system. ...

Overexpression of the c-erbB-2 gene enhanced intrinsic metastasis potential in human breast cancer -
M Tan - Cancer Research, 1997 - AACR
... has been correlated with lymph node metastasis and poor prognosis in breast cancer
patients ... overexpression of p185 can enhance the metastatic potential of ...

… Analysis of Prostate Cancer Reveals Distinct Transcriptional Programs Associated with Metastatic -
E LaTulippe, J Satagopan, A Smith, H Scher, P … - Cancer Research, 2002 - AACR
... high-throughput gene expression analysis to study prostate cancer metastases. One
reason is that well-preserved surgical tissue samples of metastatic prostate ...

CD44 is a metastasis suppressor gene for prostatic cancer located on human chromosome 11p13 -
AC Gao - Cancer Research, 1997 - AACR
... to introduce normal human chromosomes into highly metastatic rodent prostatic cancer
cells to map the location of a metastasis suppressor gene(s). Using this ...

Source: Google Scholar
 
 

Scientists link gene to metastatic cancer

SEOUL, South Korea (UPI) -- South Korean scientists have reportedly discovered a gene linked to metatastic cancers of the breast, liver and intestine.

Im Dong-soo and his colleagues at the Korea Research Institute of Bioscience and Biotechnology worked with mice to show that E2-EPF ubiquitin carrier protein triggers metatastic cells, the Korea Times reported Monday.

'By targeting the protein, which has something to do with cancers in the breast, liver and bowel, we think we will be able to come up with effective drugs in the future,' he said.

The research has been published in the journal Nature Medicine. Im and his colleagues have applied for a patent on the protein.

 
 
 
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