Cannabis "tax" nothing new PR CannaZine (press release), UK - Nov 25, 2008 Speaking to ITV chat show host Michael Parkinson, the singer said he was not "advocating" the drug for everyone, but the 43 year old mega-star added, ...
Janet Street-Porter: Two dinosaurs, two outdated world-views Independent, UK - Nov 4, 2008 Michael Parkinson and Paul O'Grady are infinitely more graceful with words. I accept that millions watch Clarkson because he embodies the mind-numbing ...
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EPL Announces Second Quarter 2008 Results StreetInsider.com (subscription), MI - The conference call will be webcast live as well as for on-demand listening at the Company's web site, www.eplweb.com. Listeners may access the call through ...EPL - NBL
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Power-One Announces Second Quarter 2008 Results MarketWatch - Jul 24, 2008 The call will be available over the Internet through the Company's investor relations Web site at www.power-one.com. To listen to the call, please go to the ...PWER
Actel Announces Second Quarter 2008 Financial Results CNNMoney.com - Jul 29, 2008 A live web cast and replay of the call will be available. Web cast and replay access information as well as financial and other statistical information can ...ACTL
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[PDF]Performance Analysis of TETRA and TAPS and Implications for Future Broadband Public Safety … - C Hoymann, D Kuypers, P Sievering, P Stuckmann, B … - Workshop on Broadband Wireless Ad-Hoc Networks and Services, …, 2002 - projectmesa.org ... e-mail size (upper 20 %) [byte] log 2 -normal 15700 62.9 ? 10 9 ... 0.1 0.2 0.3 0.4 0.5
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One million Britons who take Ecstasy every weekend are playing Russian roulette with their brains, scientists warn today.
Taking three tablets in an evening causes changes in the brain similar to those seen in people who go on to develop Parkinson's disease, research shows.
It suggests the explosion in Ecstasy use is storing up terrifying public health problems for the future.
The findings, the most devastating so far on the dangers of the drug, follow tests on monkeys and baboons.
Weeks after they were given the drug, the animals had 'extensive damage' to crucial cells in the brain that produce dopamine - a chemical which helps control body movement.
Dopamine levels were reduced by up to 80 per cent. Parkinson's results when there is a 90 per cent loss.
'The most troubling implication of our findings is that young adults using Ecstasy may be increasing their risk for developing parkinsonism, a condition similar to Parkinson's disease, as they get older,' said Professor George Ricaurte, who headed the research, details of which are published today in the journal Science.
Parkinson's-type disorders, characterised by loss of coordination, immobility and uncontrollable shaking, could set in as a result of taking the drug because brain dopamine already declines with advancing age, he said.
Professor Ricaurte, neurologist at the Johns Hopkins University School of Medicine in Baltimore, added: 'The lack of obvious immediate harmful effects of Ecstasy is partly responsible for the widely held belief that the drug is safe.
'But the use of Ecstasy in doses similar to those used in recreational settings can damage brain cells, and this can have serious effects.
'People are now using the drug in the setting of all-night parties where they take several doses through the course of the evening.
'What Ecstasy does is damage nerve endings in the brain over a period of hours.
'We don't know what happens to these injured cells long-term. But potentially, the implications are very serious. The margin of safety for Ecstasy appears to be extremely small, if any.'
Dr Alan Leshner, of the American Association for the Advancement of Science, which publishes Science, said: 'This study shows that even very occasional use can have long-lasting effects on many different brain systems.
'It sends an important message to young people: using Ecstasy is like playing Russian roulette with your brain.'
Professor John Henry, Britain's leading drug abuse expert, of St Mary's Hospital in West London, described the Baltimore findings as 'unexpected and important'.
He said some doubt remained about whether the doses given to the primates in the experiment were directly comparable with those taken by people, since two of the ten animals died, far higher than the number that would have been expected in humans.
But he added: 'It is beyond doubt that Ecstasy affects the brain and causes decrement of memory.'
Professor Andy Parrott, head of the Recreational Drugs Research Group at the University of East London, said: 'We found that 38 per cent of heavy Ecstasy users report motor dysfunction - tremors and twitches - that are more likely to be related to dopamine.
'That is consistent with these new findings.'
The report comes amid considerable debate about the legal classification of Ecstasy, with some MPs calling for the drug to be downgraded from Class A to Class B.
Previous research has shown Ecstasy, sometimes known as MDMA, can cause dramatic changes in heart rate and blood pressure.
It can lead to dehydration and death.
According to anecdotal reports, regular users can suffer severe mood swings, depression and memory loss years after giving up the drug.
Other experts say the drug appears to alter brain chemistry to produce an effect likened to permanent jet lag.
There were 56 Ecstasyrelated deaths in Britain last year, compared with 20 in 2000, 17 in 1999 and 11 in 1998.
Estimates suggest as many as one in five of those aged 15 to 25 have used Ecstasy, with up to five million pills consumed each week.
Dealers in many areas have slashed prices. One tablet costs on average £3, but as little as £1.25 in some areas.
