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Recent News and Articles on the Keywords: cancer + against + breast  Related to the article below (Last Update: 8/4/2008)


Ottawa Citizen
How will cancer news affect Christina Applegate's Emmy bid?
The Envelope, CA -
The news that Christina Applegate is battling breast cancer comes just as Emmy judges are watching the nominees' sample DVDs and checking off ballots to ...
AssociatedPress
Applegate is treated for breast cancer Carlsbad Current Argus
Personalities: John Cusack, Christina Applegate, Annie Lennox ... Poughkeepsie Journal
FanIQ
all 971 news articles »
Editors' Notebook: Why we?re going ?Against the Tide?
Harwich Oracle, MA -
It?s why we decided this year to participate in the Against the Tide breast cancer prevention fund-raiser happening at Nickerson State Park in Brewster on ...
Starkey Speaks at Men Against Breast Cancer
LSUSports.net, LA - Aug 1, 2008
The organization also targets and mobilizes men to be active participants in the fight to eradicate breast cancer as a life threatening disease. ...
Essex County Sheriff?s Department Employees Golf Tournament
Wicked Local Middleton, MA -
All money raised will be donated toward breast cancer prevention research and prevention education initiatives conducted by the Massachusetts Breast Cancer ...
Relay for Life of Grand County makes great strides in second year
Sky Hi Daily News, CO -
Breast cancer survivor Penny Hamilton was one of 15 cancer survivors who walked in the Survivors Lap at the start of the relay. ?It was festive,? she said. ...
City pub event boosts new cancer charity's funds
Express & Echo, UK -
The Showman pub, in St Thomas, organised a bingo session and pink-themed raffle to raise money for the charity Against Breast Cancer. ...
Fight against breast cancer has Clinic seeing pink
Great Falls Tribune, MT - Jul 31, 2008
Those were just a few of the contestants in Clinic Cancer Care's second annual Prettiest in Pink contest. The event is a fundraiser for Women Against Breast ...
In Vietnam, Alongside Progress, A Battle For Life With The ...
Medical News Today (press release), UK -
The diagnosis: advanced breast cancer. The treatment: radical mastectomy, followed by chemotherapy, then 25 fractions of radiotherapy spread over five weeks ...
Smart Levels Media Helping Raise Money To Find A Cure For Breast ...
PowerHomeBiz.com (press release) -
We all want to win the fight against cancer, and being able to support a local organization like the Susan G. Komen Orange County affiliate allows us to ...
Battle against breast cancer
The Vail Trail, CO - Jul 30, 2008
Each year, the annual ?Celebration of Life? Breast Cancer Awareness luncheon reaches new heights. I thought it impossible to match last year?s event with ...
Source: Google News

… plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2 -
DJ Slamon, B Leyland-Jones, S Shak, H Fuchs, V … - New England Journal of Medicine, 2001 - content.nejm.org
... Activity of Suberoylanilide Hydroxamic Acid Against Human Breast Cancer Cells with
Amplification of Her-2. Clin Cancer Res 11: 6382-6389 [Abstract] [Full Text]; ...

Protection against breast cancer with genistein: a component of soy -
CA Lamartiniere - American Journal of Clinical Nutrition, 2000 - Am Soc Nutrition
... Clinical Nutrition Article. Protection against breast cancer with genistein:
a component of soy 1 ,2 ,3. Coral A Lamartiniere 1 From ...

… A Is a Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer in Vivo -
DM Vigushin, S Ali, PE Pace, N Mirsaidi, K Ito, I … - Clinical Cancer Research, 2001 - AACR
... Preclinical Pharmacology. Trichostatin A Is a Histone Deacetylase Inhibitor with
Potent Antitumor Activity against Breast Cancer in Vivo 1. ...

… antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer … -
J Baselga, L Norton, J Albanell, YM Kim, J … - Cancer Res, 1998 - ncbi.nlm.nih.gov
... anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and
doxorubicin against HER2/neu overexpressing human breast cancer xenografts. ...

… CONTRIBUTIONS Independent Protective Effect of Lactation against Breast Cancer: A Case-Control … -
KY Yoo, K Tajima, T Kuroishi, K Hirose, M Yoshida, … - American Journal of Epidemiology, 1992 - Oxford Univ Press
... Printed in USA AO rights reserved ORIGINAL CONTRIBUTIONS Independent Protective
Effect of Lactation against Breast Cancer: A Case-Control Study in Japan ...

Specific protection against breast cancers by cyclin D1 ablation -
Q Yu, Y Geng, P Sicinski - Nature, 2001 - nature.com
... cyclin D1 -/- mice against breast cancers. To address this possibility, we crossed
cyclin D1 -/- mice with four different strains of breast-cancer-prone mouse ...

… 4-aminophenyl) benzothiazoles and evaluation of their activities against breast cancer cell lines in … -
DF Shi, TD Bradshaw, S Wrigley, CJ McCall, P … - J. Med. Chem, 1996 - pubs.acs.org
... 3. 1 Synthesis of 2-(4-Aminophenyl)benzothiazoles and Evaluation of Their Activities
against Breast Cancer Cell Lines in Vitro and in Vivo. ...

Does pregnancy immunize against breast cancer? -
B Agrawal - Cancer Research, 1995 - AACR
... Research. ARTICLES. Does pregnancy immunize against breast cancer? B ... Multiparity
has been linked with protection against breast cancer. T cells ...

Cytotoxic activity of epidermal growth factor-genistein against breast cancer cells. -
FM Uckun, RK Narla, X Jun, T Zeren, T … - Clin Cancer Res, 1998 - ncbi.nlm.nih.gov
Clin Cancer Res. 1998 Apr;4(4):901-12. Click here to read Cytotoxic activity of
epidermal growth factor-genistein against breast cancer cells. ...

Growth inhibition of human breast cancer cells in vitro with an antibody against the type I … -
CL Arteaga - Cancer Research, 1989 - AACR
... Research. ARTICLES. Growth inhibition of human breast cancer cells in vitro
with an antibody against the type I somatomedin receptor. CL ...

Source: Google Scholar
 
 

Pro-vitamin E Shown To Be Active Against Breast Cancer Cells

Article Date: 14 Dec 2006 - 5:00 PST
A precursor of vitamin E has been shown to be effective against breast cancer cell lines which over-express human epidermal growth factor receptor (HER2).

About 30% of breast cancers exhibit high levels of HER2 - a feature that appears to make the disease resistant to many common treatments including chemotherapeutic agents.

Now researchers in Griffith University's School of Medical Science have shown that pro-vitamin E or alpha-tocopheryl succinate can reduce tumour volume in experimental animals with high levels of HER2.

Chief investigator Associate Professor Jiri Neuzil said alpha-tocopheryl succinate (alpha-TOS) had the potential to be an inexpensive, safe and selective therapy for hard-to-treat breast cancers.

"Alpha-TOS has already shown promise as a potent anticancer agent in diseases such as colon cancer and mesothelioma. It induces controlled cell death or apoptosis in tumour cells."

Article continues below and (thank you)
 
Transgenic mice with high HER2 breast cancers were treated over a three week period and tumour size was monitored every three days by ultrasound imaging.

The high resolution ultrasound allows for more accurate measurement of tumour volume than any other non-invasive technique.

The research team found that while alpha-TOS is effective alone, it can be delivered into the tumour cells more efficiently when given in a conjugate form with a targeting peptide.

"Tumour volume reduced more than 50% when animals were treated with the conjugate rather than free alpha-TOS," Associate Professor Neuzil said.

He said one of the benefits of alpha-TOS as a potential anti-cancer drug was that it was metabolised in the liver to vitamin E and unlikely to cause dangerous side effects.

Associate Professor Neuzil is presenting his results at the Gold Coast Health and Medical Research Conference. The conference, an initiative of the Griffith Institute of Health and Medical Research, is being held December 14-15, at the Radisson Palm Meadows Resort, Gold Coast.

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Contact: Mardi Chapman
Research Australia
 
 
 
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