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Recent News and Articles on the Keywords: malaria + 0.26 + parasitic  Related to the article below (Last Update: 8/4/2008)

Reduction of transmission from malaria patients by artemisinin ...
7thSpace Interactive (press release), NY - Jul 9, 2008
Artemisinin combination therapies (ACT), which are increasingly being introduced for treatment of Plasmodium falciparum malaria, are more effective against ...
Source: Google News

Genetic relationships between parasite virulence and transmission in the rodent malaria Plasmodium … -
MJ Mackinnon, AF Read - Evolution, 1999 - JSTOR
... gametocytemia Transmission 5. Maximum gametocytemia (0.26) (0.30) (0.31 ... Malaria renders
mice suscep- 701. MJ MACKINNON AND AF ... The evolution of parasitic diseases ...

[CITATION] Genetic and environmental determinants of malaria parasite virulence in mosquitoes -
HM Ferguson - Proceedings of the Royal Society B: Biological Sciences, 2002 - The Royal Society
... 1220 HM Ferguson and AF Read Malaria parasitic virulence in ... size (F 1,14 = 1.36,
p = 0.26) or anaemia ... mortality varies signi cantly with parasite genotype in ...

The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is … -
BJ Foth, LM Stimmler, E Handman, BS Crabb, AN … - Molecular Microbiology, 2005 - Blackwell Synergy
... www.ncbi.nih.gov/projects/Malaria/plasmodiumblcus.html ... For Western blot analysis,
parasite proteins from ... 2 U of phosphotransacetylase (Sigma) and 0.26 ?g of ...

lmmunitv to malaria during pregnancv: Different hosf, different parasite
PE Duffy - Malaria in Pregnancy: Deadly Parasite, Susceptible Host, 2001 - books.google.com
... examined the frequenc t of different parasite species infecting ... Frequencv of mixed
parasitemias causing pregnancv malaria Studv'and ... 4S 1. 8 20.8 2.2 0.26 13 3.1 ...

Virulence of mixed-clone and single-clone infections of the rodent malaria Plasmodium chabaudi -
LH Taylor, MJ Mackinnon, AF Read - Evolution, 1998 - JSTOR
... VIRULENCE OF MIXED INFECTIONS OF MALARIA 585 infection (PI ... blood count (F1,11 = 0.27,
Fl,11 = 0.26, F1,11 ... clone infections with initial CR:ER parasite ratios of ...

Emergence of a new neotropical malaria vector facilitated by human migration and changes in land use -
JE Conn - The American Journal of Tropical Medicine and Hygiene, 2002 - ASTMH
... 05/97 MJA 1144 0.26 0 0.70 0.70 90 0 ... to mem- bers of the Programa de Controle de
Malaria. ... A. Wirtz, Entomology Branch, Division of Parasitic Diseases, Centers ...

Why is the effect of malaria parasites on mosquito survival still unresolved? -
HM Ferguson, AF Read - Trends in Parasitology, 2002 - Elsevier
... counterparts (Table 3) and that overall, malaria does reduce ... size and sample size
(P = 0.26, n = 24 ... of natural combinations of vector and parasite species, ten ...

… AND SCHISTOSOMA HAEMATOBIUM: PROTECTIVE EFFECT OF SCHISTOSOMIASIS ON MALARIA IN SENEGALESE CHILDREN … -
V BRIAND, L WATIER, JY LE HESRAN, A GARCIA, M COT - The American Journal of Tropical Medicine and Hygiene, 2005 - ASTMH
... As expected, we observed that malaria parasite density decreased with age. ... more often
than girls, the association remained (? = ? 0.26, 95% confidence ...

Malaria therapy reinoculation data suggest individual variation of an innate immune response and … -
L Molineaux, M Tr?uble, WE Collins, GM Jeffery, K … - Transactions of the Royal Society of Tropical Medicine and …, 2002 - Elsevier
... or l? ovale, and whose second malaria inoculation was ... Heterologous 18 0.26
(-0.14,0.58) 0.53 (0.28, 0.79 ... the first local maxi- mum asexual parasite density ( ...

[PDF] Sex ratio and virulence in two species of lizard malaria parasites -
J Pickering, AF Read, S Guerrero, SA West - Evolutionary Ecology Research, 2000 - thereadgroup.net
... We studied two malaria parasite species, P. ?tropiduri? and P ... seen in other species
of lizard malaria (Schall, 1989 ... female bias in P. balli (0.26) than in P ...

Source: Google Scholar
 
 

Examining Genetic Variability Of Malaria Parasite Offers Insight

Article Date: 14 Dec 2006 - 11:00 PST
WHAT: Back-to-back papers published online in Nature Genetics reveal important new details about the genetic variability of the malaria parasite and provide new clues for how it causes disease. One paper, funded in part by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), reports the results of a massive effort to sequence and compare complete or partial genomes of 54 different samples from around the globe of the most deadly type of malaria parasite, Plasmodium falciparum. The sequencing, carried out in part at NIAID's Microbial Sequencing Center, has revealed nearly 47,000 genetic variations in the parasite's genome. The genetic diversity captured by this map will help researchers understand the parasite's evolution and study malarial drug resistance. Two companion studies being published simultaneously include one led by NIAID scientists that identifies new antigens--pieces of the pathogen that are recognized by the immune system. Some of these new antigens may be potential targets for new therapeutics or vaccines to help control malaria.

###

ARTICLES: "A genome-wide map of diversity in Plasmodium falciparum," by S Volkman et al. Nature Genetics DOI: 10.1038/ng1930 (2006). This study was conducted by scientists at the Harvard School of Public Health; the Broad Institute of the Massachusetts Institute of Technology and Harvard; Cheikh Anta Diop University in Dakar, Senegal; the Whitehead Institute for Biomedical Research; and Harvard Medical School.

Article continues below and (thank you)
 
"Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome," by J Mu et al. Nature Genetics DOI: 10.1038/ng1924 (2006). This study was conducted by scientists in NIAID's Laboratory of Malaria and Vector Research; North Carolina State University; and the University of Oxford.

SPOKESPERSONS: Martin John Rogers, Ph.D., Parasite Biology/Parasite Genomics Program Officer, Parasitology and International Programs Branch, NIAID Division of Microbiology and Infectious Diseases for the article by S Volkman et al.

Maria Y. Giovanni, Ph.D., Assistant Director for Microbial Genomics and Advanced Technology, NIAID Division of Microbiology and Infectious Diseases, can comment on NIAID's Microbial Sequencing Center.

Xinzhuan Su, Ph.D., Senior Investigator and Head of the Malaria Genomics Section, NIAID Laboratory of Malaria and Vector Research for the study by J Mu et al.

NIAID is a component of the National Institutes of Health. NIAID supports basic and applied research to prevent, diagnose and treat infectious diseases such as HIV/AIDS and other sexually transmitted infections, influenza, tuberculosis, malaria and illness from potential agents of bioterrorism. NIAID also supports research on basic immunology, transplantation and immune-related disorders, including autoimmune diseases, asthma and allergies.

The National Institutes of Health (NIH)--The Nation's Medical Research Agency--includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov/.

Contact: Jason Socrates Bardi
NIH/National Institute of Allergy and Infectious Diseases
 
 
 
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