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Recent News and Articles on the Keywords: healing + 0.34 + insulin  Related to the article below (Last Update: 8/4/2008)


Jamaica Gleaner
Petersfield Sunset Healing Mountain
Jamaica Gleaner, Jamaica -
A friend, who had tried Sunset Heal Mountain Retreat and Healing Centre in Petersfield, Westmoreland, did such a great job of selling me the place, ...
Reiki had initial problems gaining acceptance, but users find a ...
Irish Times, Ireland -
REIKI IS a spiritual philosophy and complementary hands-on healing technique, during which a therapist channels universal life-force energy through their ...
Doctors learn healing qualities of an apology
National Post, Canada - 7 minutes ago
Her course of chemotherapy finished, the Winnipeg cancer patient headed home with a blister pack of what were supposed to be anti-nausea pills. ...
Burkhart Healing After Big Crash at X Games
AMASupermoto.com, OH -
Mark Burkhart (Graves Motorsport Yamaha), 2008 Moto X World Champion, 2007 X-Games Supermoto Gold winner, and 2007 AMA Supermoto Champion is healing back at ...
New Medical Center Serves as National Model of Design, Healing and ...
Earthtimes (press release), UK -
... of hospitality and health care design to create a place that promotes healing and wellness and lifts the spirits of patients, visitors and employees. ...
Self-Healing Hardware: Not Always A Good Thing
Washington Post, United States -
I had the opportunity to ponder this paradox earlier today. I'd showed up at a Sprint service center on L Street downtown to get a malfunctioning phone ...
Healing help
Edmonton Sun,  Canada -
By KEVIN CRUSH, SUN MEDIA Thousands of people across Canada are mourning beheading victim Tim McLean Jr., with at least 18 Internet groups calling for a ...
Knee healing on time
In-Forum, ND - Aug 3, 2008
Washington said his knee is still healing. There?s still some inflammation, he said. ?With his speed and his ability, it?s hard to keep him off the field,? ...
?It was a healing time?
Albany Democrat Herald, OR - 23 minutes ago
?It was beautiful,? she said. ?It was a healing time for a lot of people. It was great, and it was a huge help to have them go through the tall corn.?
Healing through hypnosis
St. Joseph News-Press, MO -
In her own life, Ms. Frederick experienced healing through hypnosis while attending the Hypnotherapy Academy of America in Santa Fe, NM, in 2006. ...
Source: Google News

Effect of insulin-like growth factor I (IGF-I) administration on the healing of colonic anastomoses … -
TI Petersen, P Kissmeyer-Nielsen, A flyvbjerg, S … - International Journal of Colorectal Disease, 1996 - Springer
... soit par l'interm6diaire d'un insulin-like facteur de ... anastomoses in the important
early healing phase. ... 8.18 (1.35) Energy absorption (newton) 0.34 (0.04) 0.28 ...

Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in … -
AP Furnary, KJ Zerr, GL Grunkemeier, A Starr - The Annals of Thoracic Surgery, 1999 - Soc Thorac Surgeons
... that continuous intravenous insulin infusion induced a significant decrease in the
risk of deep sternal wound infection (p 0.005; relative risk, 0.34), whereas ...

The effects of blood glucose control upon fracture healing in the BB Wistar rat with diabetes … -
H BEAM - Journal of Orthopaedic Research, 2002 - doi.wiley.com
... early and late parameters of fracture healing in DM ... Fourteen days after insulin
treatment, a closed middiaphyseal fracture ... 5.62 f 0.50 1.79 zt 0.34",b 5.70 i ...

… , transforming growth factor-alpha, acidic fibroblast growth factor, insulin-like growth factor-I, … -
JL Andresen, N Ehlers - Current Eye Research, 1998 - ingentaconnect.com
... early stages of corneal stromal wound healing, we performed ... Insulin is a peptide
hormone of a comparable ... 1.4 ? 0.12 1.5 ? 0.30 ? 1.8 ? 0.34 1.6 ? 0.23 ...

[CITATION] The Stimulating Effect of Growth Hormone on Fracture Healing Is Dependent on Onset and Duration of … -
BUE BAK, PH JBRGENSEN, TTOW ANDREASSEN - Clinical Orthopaedics and Related Research, 1991
... indirectly by increasing the responsiveness to insulin- like growth ... on the Biomechanical
Properties of Healing Tibia1 Fractures ... f 5.9 263.9 f 42.0* 0.34 f 0.04 ...

Pulp-capping with recombinant human insulin-like growth factor I (rhIGF-I) in rat molars -
H Lovschall, O Fejerskov, A Flyvbjerg - Advances in Dental Research, 2001 - IADR
... Key Words Insulin-like growth factor I, pulp capping ... The pulp-healing response to
growth factor-gel capping was ... 9 7 16 0.34 ? 0.12 0.29 ? 0.04 p > 0.26 ...

Effect of growth hormone replacement on wound healing in healthy older men -
MA Papadakis, G Hamon, N Stotts, MJ Tierney, E … - Wound Rep. Reg., 1996 - Blackwell Synergy
... that GH andits effector arm in adults, insulin-like growth ... ePTFE sample to assess
the wound healing poten- tial ... IGF-1 levels (r = 0.29, p = 0.34), treatment IGF ...

Insulin-like growth factor-l blood levels in severely burned patients: effects of time post injury, … -
T Abribat, P Brazeau, I Davignon, DR Garrel - Clinical Endocrinology, 1993 - Blackwell Synergy
... Moreover, it improves wound healing when adminis- tered with IGF ... 4 Insulin-like growth
factor I concentrations in A ... 0.56 -0.70* -0.75** D/u TBSA burn -0.34 -0.L7 ...

Correlation of proliferative and anti-apoptotic effects of HGF, insulin, IGF-1, IGF-2, and EGF in … -
R Yanai, N Yamada, M Inui, T Nishida - Experimental Eye Research, 2006 - Elsevier
... into the regulatory mechanisms of homeostasis and wound healing in the ... nM PDGF-BB,
0.33 nM TGF-? 1 , 0.34 nM TGF-? 2 , 35 nM HGF, 35 nM insulin, 39.9 nM ...

… sequentially exposed to transforming growth factor- 1 in monolayer and insulin-like growth factor-I … -
AA Worster, BD Brower-Toland, LA Fortier, SJ Bent, … - J Orthop Res, 2001 - doi.wiley.com
... taining insulin-like growth factor I (IGF-I). Bone marrow aspirates and chondrocytes
were ... of OA is due in part to the minimal in- trinsic healing capacity of ...

Source: Google Scholar
 
 

Why Applying Insulin To Wounds Significantly Enhances Healing

Article Date: 14 Dec 2006 - 13:00 PST
Insulin is a hormone known primarily for regulating sugar levels in the blood, yet researchers at the University of California, Riverside, recently found that applying insulin directly to skin wounds significantly enhanced the healing process.

Skin wounds in rats treated topically with insulin healed faster"surface cells in the epidermis covered the wound more quickly and cells in the dermis, the deeper part of the skin, were faster in rebuilding blood vessels.

In follow-up studies of human skin cells in culture, Manuela Martins-Green and colleagues explored the molecular impact of topical insulin on keratinocytes, the cells that regenerate the epidermis after wounding, and on microvascular endothelial cells, the cells that restore blood flow.

Using various cell and molecular techniques, the researchers discovered that insulin stimulates human keratinocytes in culture to proliferate and migrate. In cultured human microvascular endothelial cells, the insulin stimulates only migration into the wound tissue. The insulin works by switching on cellular signaling proteins called kinases (specifically Src, PI3K, and Akt) and a protein (SREBP) that binds elements in DNA that regulate the production of cholesterol and its relatives.

Article continues below and (thank you)

 
Chronic or nonhealing wounds take an immense toll on American health and on health care systems. It particularly affects millions of patients with impaired mobility, as well as those with diabetes. Because diabetes is a disease caused by impaired production or utilization of insulin, this work may help explain the connection between diabetes and poor healing.

Says Martins-Green, "This work is important because when we know which cells respond to insulin and which molecules are involved, we may be able to develop ways in which we can make insulin work even better or find ways in which more affordable molecules that mimic these functions of insulin can be developed to treat people who suffer from poor healing."

###

Insulin and Healing: Cell and Molecular Mechanisms Leading to Acceleration of Wound Healing

Y. Liu, M. Yao, M. Martins-Green

Contact: John Fleischman
American Society for Cell Biology
 
 
 
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