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Recent News and Articles on the Keywords: obesity + 148 + cancer  Related to the article below (Last Update: 8/4/2008)

A Clinical Nutrition Course to Improve Pharmacy Students' Skills ...
RedOrbit, TX - Jul 30, 2008
2002;25:148-98. 10. World Cancer Research Fund and American Institute for cancer Research. Food, nutrition, and the prevention of cancer: a global ...
Geriatric Screening and Preventive Care
RedOrbit, TX - Jul 16, 2008
I it reduces the rate of all-cause mortality and helps to prevent osteoporosis and obesity.14 a regular exercise program is an integral part of any ...
Endokrynologia - postępy 2007
Medycyna Praktyczna, Poland - Aug 1, 2008
Gelsolin: a novel thyroid hormone receptor-beta interacting protein that modulates tumor progression in a mouse model of follicular thyroid cancer. ...
Source: Google News

A prospective study of obesity and cancer risk (Sweden) -
A Wolk, G Gridley, M Svensson, O Nyr?n, JK … - Cancer Causes and Control, 2001 - Springer
... 29 years of follow-up among patients with obesity (only ?rst ... All cancer (140?209)
500 1.25 1.14?1.36 1477 1.37 ... Buccal (140?148) 13 1.1 0.6?1.9 13 0.9 0.5 ...

Obesity in youth and middle age and risk of colorectal cancer in men -
L Marchand, LR Wilkens, MP Mi - Cancer Causes and Control, 1992 - Springer
... Indeed, obesity has been associated rather consistently ... identified 737 male and
148 female histologically confirmed colorectal-cancer cases for ...

Obesity, body size, and risk of postmenopausal breast cancer: the Women's Health Initiative (United … -
LM Morimoto, E White, Z Chen, RT Chlebowski, J … - Cancer Causes and Control, 2002 - Springer
... Obesity, body size and breast cancer 745 ... a -adjusted relative risk (RR) of breast
cancer by anthropometric ... 22.6?24.9 41 1.13 0.63?2.04 148 0.84 0.64?1.09 ...

Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? -
JS Yudkin, M Kumari, SE Humphries, V Mohamed-Ali - Atherosclerosis, 2000 - Elsevier
... Atherosclerosis Volume 148, Issue 2, 1 February 2000 ... healthy subjects-associations
with obesity, insulin resistance ... for interleukin-6 in cancer cachexia, Cancer ...

Obesity and colorectal cancer risk in women -
PD Terry, AB Miller, TE Rohan - British Medical Journal, 2002 - gut.bmj.com
... For analyses by colon cancer subsite, proximal colon cancers ... to the sigmoid colon
(n=148); the location of ... according to the criteria for obesity established by ...

The role of the novel adipocyte-derived hormone adiponectin in human disease -
JJ Diez, P Iglesias - European Journal of Endocrinology, 2003 - eje.org
... 0.1480293 European Journal of Endocrinology, Vol 148, Issue 3 ... Implications for Features
of Obesity Obesity, December 1 ... Home page, J Natl Cancer Inst Home page EK ...

Diabetes, Body Size, and Risk of Endometrial Cancer -
SM Shoff, PA Newcomb - American Journal of Epidemiology, 1998 - Oxford Univ Press
... confers no additional risk of endometrial cancer in women ... Am J Epidemiol
1998;148:234-40 ... dependent; endometrial neoplasms; logistic models; obesity in diabetes ...

Obesity, adipocytokines, and insulin resistance in breast cancer -
DP Rose, D Komninou, GD Stephenson - Obesity Reviews, 2004 - Blackwell Synergy
... cells, and hyperinsulinaemia and the insulin resistance syndrome are likely candidates
for a mechanism by which obesity affects breast cancer risk and ...

Breast Cancer and Obesity: An Update -
GD Stephenson, DP Rose - Nutrition and Cancer, 2003 - Lawrence Earlbaum
... Despite the emphasis on estrogens to explain the effects of obesity on breast cancer,
other factors may prove to be equally or more important, particularly as ...

… study of diabetes, obesity, physical activity and risk of endometrial cancer among Mexican women -
E Salazar-Mart?nez, EC Lazcano-Ponce, GG Lira-Lira … - Cancer Causes and Control, 2000 - Springer
... 27. Sho? SM, Newcomb PA (1988) Diabetes, body size, and risk of endometrial cancer.
Am J Epidemiol 148: 234?240. Diabetes, obesity and endometrial cancer 711

Source: Google Scholar
 
 

Obesity 'to fuel rise in cancers'

Soaring obesity levels could result in up to 12,000 cases of weight-related cancer being diagnosed annually in the UK by 2010, say experts.

The Department of Health predicts a 14% increase in obesity by 2010, which will mean 27.6 million people in the UK will be classified as obese. Cancer Research UK has calculated that this will lead to around 1,500 extra weight-related cancers a year.

Researchers have estimated that excess weight causes 3.8% of cancers.

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The most recent figures show that in 2003 there were 24.2 million obese or overweight people in the UK.

The projected rise means that weight-related cancers are likely to rise from 10,500 cases per year to 12,000 in just seven years.

After smoking obesity is one of the most important preventable causes of cancer.

Lack of awareness

But few people are aware that being overweight or obese increases the risk of developing the disease.

A Cancer Research UK survey found that only 29% of overweight or obese people were aware of the cancer connection.

Professor Tim Key, an expert on diet and cancer, said: "It is now well established that being overweight increases the risk of developing several types of cancer.

"The effects on breast and womb cancer are almost certainly due to the increased production of the hormone oestrogen in the fatty tissue.

"We are less sure of the precise mechanisms in other obesity related cancers but we can confidently predict that the number of these cases will increase unless the rise in obesity in Britain can be reversed."

Research in the US has found that among men and women who have never smoked the risk of overall cancer death is increased by up to a third in obese people.

Cancer Research UK is calling for a comprehensive strategy to halt the rise in obesity in the UK, which must be particularly targeted at children and young adults.

Women who are overweight or obese are at increased risk of womb cancer and postmenopausal women have a greater risk of developing breast cancer.

There is also evidence for a link between obesity and cancers of the bowel and kidney.

Poor survival

Obese people who develop cancer are also less likely to survive than those with a healthy weight, possibly because the cancer is more difficult to diagnose and is therefore not treated until it is more advanced.

Dr Lesley Walker, the charity's director of cancer information, said: "Eating healthily and exercising regularly is the best way to maintain a healthy body weight and to reduce your cancer risk."

In the UK 23% of men and 25% of women are now classified as obese.

The numbers of obese children have almost tripled in the past 20 years, with more than 5% now obese and more than 20% overweight.

 

Taste test 'may show depression'

Scientists say it may be possible to develop a taste test to diagnose depression, and determine the best drugs to treat it.

They found taste perception is altered by two brain chemicals, serotonin and noradrenaline, imbalances of which are also implicated in depression. But they affect taste in different ways, so a taste test could potentially show which was causing illness. The University of Bristol study appears in the Journal of Neuroscience.

However, an independent expert has cast doubt on the usefulness of the findings.

 
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During the trial, 'healthy' volunteers were given two anti-depressant drugs, which raised the levels of both chemicals in their brain.

Increased serotonin levels appeared to improve sensitivity to sweet and bitter tastes, while increased noradrenaline levels appeared to improve sensitivity to bitter and sour tastes.

Exciting breakthrough

Lead researcher Dr Lucy Donaldson said: "Because we have found that different tastes change in response to changes in the two different neurotransmitters, we hope that using a taste test in depressed people will tell us which neurotransmitter is affected in their illness."

Dr Jan Melichar, the lead psychiatrist in the study, said: "This is very exciting. Until now we have had no easy way of deciding which is the best medication for depression.

"As a result, we get it right about 60-80% of the time. It then takes up to four weeks to see if the drug is working, or if we need to change it.

"However, with a taste test, we may be able to get it right first time."

The findings also suggest somebody who is anxious or stressed will have a less sensitive sense of taste - which may explain why people with depression have a diminished appetite.

Professor Dave Kendall, an expert on depression at the University of Nottingham, said the research was interesting - but was unlikely to be able to determine which drugs a patient should take.

"The most efficacious antidepressants are relatively dirty drugs that enhance the availability of both noradrenaline and serotonin.

"So knowing which of these neurotransmitters is dysfunctional doesn't really matter."

 

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