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Recent News and Articles on the Keywords: new + vaccine + drive  Related to the article below (Last Update: 8/4/2008)

Abbott faces Norvir suit; Vaccine may cure Black Death;
FierceHealthcare, DC -
The suit, like some others, accuses Abbott of hiking the price of Norvir to stifle competition from other drugs and drive patients to its combo drug Kaletra ...
Response To Drug Industry?s Criticism: Trial Lawyers Drive ...
NewYorkInjuryNews, New York -
Abusive personal injury lawyers extract punitive verdicts against selfless vaccine manufacturers from unthinking, sympathetic juries. Such verdicts drive ...
Gilead AIDS Drugs May Hold Key to Prevent Infections (Update3)
Bloomberg -
s AIDS vaccine, along with similar disappointing results from gels designed to protect women from HIV, have sent researchers in search of new preventive ...GILD
AIDS Infections 40% Higher Than US Has Estimated (Update2)
Bloomberg - Aug 2, 2008
The new US data serves as a reminder of the importance of developing an effective HV vaccine, said Larry Corey, principal investigator of the US-funded HIV ...
XVII International AIDS Conference Opens Amid Calls for Universal ...
Kaiser network.org, DC -
Disappointing news in the field of HIV vaccine research came last year when Merck halted clinical trials of an experimental vaccine over safety concerns, ...
New evidence to be presented at Aids meeting
The South African Star, South Africa - Aug 3, 2008
"HIV has spawned an interest in health systems that was never there before, and (investment in HIV) is helping to drive the expansion of public health ...
Community Briefly: Mansfield to have its first Night Out
Shreveport Times, LA - Aug 3, 2008
Vaccine is provided through the Louisiana Office of Public Health's Vaccine for Children Program. n Monday: Albertson's, 3121 Texas St. in Bossier City. n ...
Minister launches cancer jab drive
The Press Association - Jul 30, 2008
A campaign to raise awareness of a new vaccination programme against cervical cancer is due to be launched by public health minister Shona Robison. ...
In This Week's Issue
BioRegion News, NY -
The new lab will provide ?good laboratory practice? or GLP toxicology, immunology, vaccine, and bioanalytical services. "China is becoming a very attractive ...
Pencils, Paper And A Shot
WFMY News 2, NC -
The Tdap vaccine can protect adolescents and adults against three serious diseases: tetanus, diphtheria, pertussis; all caused by bacteria and are spread ...
Source: Google News

Progress on new vaccine strategies for the immunotherapy and prevention of cancer -
JA Berzofsky, M Terabe, SK Oh, IM Belyakov, JD … - J. Clin. Invest, 2004 - Am Soc Clin Investig
... 10, Room 6B-12, 10 Center Drive (MSC#1578 ... immunologic advances and the novel vaccine
strategies arising ... as the early clinical trials studying new approaches to ...

A? toxicity in Alzheimer?s disease: globular oligomers (ADDLs) as new vaccine and drug targets -
WL Klein - Neurochemistry International, 2002 - Elsevier
... for Neuroscience, 2153 North Campus Drive, Evanston, IL ... soluble A?-derived neurotoxins,
and that vaccination has neutralized ... years has given us a new view of ...

Exploring transgenic plants as a new vaccine source -
AS Moffat - Science, 1995 - sciencemag.org
... And if that were to occur, it would likely drive smaller companies out of business,
says Barton, because "you would have to have ... As a New Vaccine Source ...

Progress on new vaccine strategies against chronic viral infections -
JA Berzofsky, JD Ahlers, J Janik, J Morris, SK Oh, … - Journal of Clinical Investigation, 2004 - pubmedcentral.nih.gov
... Progress on new vaccine strategies against chronic viral infections. ... correspondence
to: Jay A. Berzofsky, Vaccine Branch, Center ... 6B-12, 10 Center Drive (MSC#1578 ...

[PDF] New hope for an AIDS vaccine -
HL Robinson - Nat Rev Immunol, 2002 - lsic.ucla.edu
... The new vaccines, which include DNA vaccines and ... Vaccine Research Center and Yerkes
Primate Research Center of Emory University, 954 Gatewood Drive,NE, Atlanta ...
-

[PDF] Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell … -
DG Brockstedt, KS Bahjat, MA Giedlin, W Liu, M … - Nature Medicine, 2005 - cerus.com
... We developed a new class of vaccines, based ... intracellular pathogen to test this vaccine
concept.L ... 1 Cerus Corporation, 2411 Stanwell Drive, Concord, California ...
-

Protection against tuberculosis by a plasmid DNA vaccine -
DB Lowrie, CL Silva, MJ Colston, S Ragno, RE … - Vaccine, 1997 - Elsevier
... Both promoters effectively drive expression of mycobacterial genes in ... it would be
surprising if new candidates are ... a vaccine that gives protection equal to BCG ...

MEDICINE: Enhanced: The Need for a Global HIV Vaccine Enterprise -
RD Klausner, AS Fauci, L Corey, GJ Nabel, H Gayle, … - Science, 2003 - sciencemag.org
... Thus, creative new public and public-private partnerships are necessary to drive
the vaccine discovery effort, with industry's development expertise a key ...

Cognitive processes and the decisions of some parents to forego pertussis vaccination for their … -
JR Meszaros, DA Asch, J Baron, JC Hershey, H … - Journal of Clinical Epidemiology, 1996 - Elsevier
... must incorporate an understanding of the cognitive processes that help drive these ...
Subjects were told that the new vaccine has not yet been tested on large ...

The cost-effectiveness of varicella vaccine programs for Australia -
PA Scuffham, AV Lowin, MA Burgess - Vaccine, 1999 - Elsevier
... These costs were based on per capita costs from New Zealand and ... annual purchases
and competition between manufacturers of the vaccine may drive the price ...

Source: Google Scholar
 
 

WHO launches new drive for malaria vaccine by 2015

Last Updated: 2006-12-04 9:12:21 -0400 (Reuters Health)

BANGKOK - The World Health Organization launched a new global effort on Monday to find a vaccine against malaria, which infects up to 500 million people each year, and the donors to pay for it.

The Malaria Vaccine Technology Roadmap aims to develop and license a first generation vaccine by 2015 against the mosquito-borne disease that kills more than one million people a year, mainly African children."The Roadmap marks the first concerted global attempt at mapping out a shared plan of action for making a preventive malaria vaccine reality," Marie-Paule Kieny, a top WHO official, said on the sidelines of a vaccine conference in Bangkok.Malaria is one of the world's oldest diseases, but only $79 million was invested on researching a vaccine in 2004, according to a report by the Malaria Research and Development Alliance.

That is a fraction of the money spent on finding a cure for HIV/AIDS or, more recently, the H5N1 bird flu virus that has killed 154 people since 2003 but has fanned fears of a global human pandemic.

Article continues below and (thank you)

 

For years, malaria was not seen as a profitable area of research, but that is changing slowly through private-public partnerships, said Zarifah Hussain Reed, a WHO expert on vaccine and immunization issues.

"The attention drives the research. That's not to say bird flu doesn't deserve the attention, but it should not be about one disease hijacking the agenda," she told reporters.

The Roadmap aims to have a first-generation vaccine by 2015 that is 50-percent effective and would last longer than one year.

It sets a goal for a second-generation vaccine by 2025 that is more than 80 percent effective and offers protection for more than four years.

The WHO said more than 30 potential vaccines are under development, but there is not enough capacity or money to test them in clinical trials, especially in countries where the disease is endemic.

To overcome these and other hurdles the Roadmap made a series of recommendations:

* Standardize procedures for assessing vaccine candidates and use the Internet to share information between laboratories and clinics

* Diversify the search for a vaccine

* Build up capacity for clinical trials in Africa and other areas where malaria is endemic

* Secure sustainable funding and develop a regulatory strategy to speed up approval of a safe vaccine.

Malaria is caused by protozoan parasites that thrive in humans and are passed between them by female Anopheles mosquitoes.

There is no vaccine against the parasite, which has grown resistant to a number of well-known antimalarial drugs, including chloroquine and pyrimethamine.

Artemisinin, a compound extracted from a Chinese herb, is regarded by medical experts as the best drug against malaria and the WHO recommended in 2001 it be used in combination with other drugs to slow down any development of resistance.

Copyright © 2006 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 

Anorexia can affect all age groups

Last Updated: 2006-12-04 9:22:51 -0400 (Reuters Health)

LONDON - Marg Oaten's daughter was a happy, healthy girl who loved table tennis and drama until at the age of 10 she developed anorexia. Twelve years on she is still fighting the illness, which almost killed her.

"I was absolutely distraught," said Oaten, 54. "It is the worst thing in the world to know your daughter might die." At her darkest point, Oaten said her daughter existed on five flakes of cereal a day, washed down with a mouthful of water.

Children as young as seven can suffer from eating disorders. The illness also afflicts older women as well as men and boys, though it is most common in young women, health experts say.

In Britain, about 5 to 10 percent of women ages 14 to 24 suffer from some form of eating disorder. The ratio falls to 1 percent for the whole female population, said Professor Janet Treasure, head of the eating disorders service and research unit at King's College London.

Bulimia nervosa, when a person binges and vomits, is two to five times more common than anorexia nervosa, when someone restricts their intake of food and drink, she said.

Both psychiatric disorders, can be fatal -- two models from Latin America died this year after becoming anorexic -- or cause permanent health defects such as brittle bones and infertility.

For Oaten's daughter, who wanted to remain anonymous, the fear of changes to her body as she approached adolescence coupled with bullying at school drove her to stop eating.

Her weight plunged and she ended up in hospital where she was treated as an inpatient and eventually allowed home. Two years later, however, she developed bulimia.

Now, at 22, she has had surgery for a prolapsed bowel and still makes herself sick, but she is trying to get better, said Oaten, who has used her experience with eating disorders to set up a support group in Hull, northern England, to help others.

CHILDREN AS YOUNG AS 7 HAVE ANOREXIA

DR Jon Goldin, a consultant child and adolescent psychiatrist at Great Ormond Street Hospital for Children in London, said: "We see children here as young as seven or eight with anorexia, but that is very rare."

Asked why youngsters develop a problem with food so early on, he said: "One contributing factor is that maybe children are under more pressure now than they were 10 or 20 years ago and somehow childhood is being prematurely shortened."

A perception in society that thin is glamorous, compounded by images of waif-like celebrities in magazines, is another of the many factors that triggers anorexia and bulimia.

But far from being sexy, the reality of the illness is lonely and desperate.

Victims say they secretly starve their bodies or binge and then vomit until there is nothing left but the taste of stomach acid on their lips. They often exercise obsessively and feel fat even when grossly underweight.

"I hated the hunger and the cold and the tiredness, but the feeling of being able to control what I ate was brilliant," said Rebecca Slack, now 23, who became anorexic when she was 15 and dropped to five stone (32 kilograms).

AGE NO BARRIER TO ANOREXIA

Young people are not the only ones at risk. Alison Alden, a married mother of three from southeast England, said starvation became a way of life when she was 43, prompted by a desire to lose weight at a time when she had been under pressure running a guest house.

Over three years, she dropped from 8 stone 7 (55 kilograms) to less than 6 stone (38 kilograms), but felt: "This couldn't be anorexia because I had never been ill in that way and I was too old."

Alden decided to get help for the sake of her family or she would die. She went to a doctor who diagnosed her as having anorexia fueled by depression. He prescribed her some anti-depressants that helped strengthen her resolve to recover.

For most sufferers, the first port of call is the doctor, who may refer him or her to an eating disorder unit at a hospital as an outpatient to receive advice on eating healthily as well as counseling to understand why the problem started.

There is no straight answer, but research has uncovered a likely genetic aspect that triggers the disorder when coupled with factors such as the onset of puberty, pressure from society to achieve, bullying and a low self-esteem, Treasure said.

Among a range of warning signs is an obsessive interest in dieting and a reluctance to eat around others, said Goldin.

It may take several years, but eating disorders can be cured and the faster they are spotted the greater the chance of recovery for people of all ages, the two experts said.

"It's all about having a reason to get better and building strategies to cope," said Alden, now 47, who has written a book , "Sleeping Dragons and Poppy Seeds," about her struggle.

Copyright © 2006 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
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