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Recent News and Articles on the Keywords: you + 3,080,000 + continues  Related to the article below (Last Update: 8/4/2008)

Deceived pal of Clark Rockefeller wonders: ?Who are you, really??
Boston Herald, United States -
And who are you, really?? ? Though ?very despondent? that his socialite ex-wife Sandra Lynne Boss, 41, had moved to London with their 7-year-old daughter ...
What The Housing Bailout Means To You
Wall Street Journal -
Of course when you get to managing your own finances in the real world, you need to pay as much attention to politics as you do to dollars and cents. ...
God wants you to be rich: 5 faith-based rules
MarketWatch -
I'll lay 'em out, you refine 'em. Nothing's wrong with getting really rich on a little faith, especially when our leaders have screwed things up so badly. ...
You?ve got Vista x64 questions, I?ve got answers
ZDNet -
Rather than try to explain that here, I?m going to refer you to a very crisply written blog post by Microsoft?s Mark Russinovich, entitled ?Pushing the ...

Wall Street Journal
Summer Job: Nice Pay, if You Can Cut It
Wall Street Journal -
It might sound odd at best, nightmarish if you're shy -- and a far cry from an elite internship at an investment bank, law firm, or media company. ...
A Cutco Sales Rep's Story Wall Street Journal
all 2 news articles »

Boston Globe
John Rash: Economy got you down? Take the long view
Minneapolis Star Tribune, MN -
"If you want price stability, it takes disciplined monetary policy. We recognize that and intend to provide that." Stern is even quicker to negate the ...
It's Rate Decision Week: Do You Know What the Fed Plans to Do with ... World Currency Watch
all 602 news articles »

Wall Street Journal
You Can't Control Animal Spirits
Wall Street Journal -
Without going into the details of how the stock-loan market works, let me assure you that this SEC action had absolutely no effect on anyone's ability to ...
What do you think of the choices on kids' menus?
Atlanta Journal Constitution,  USA -
Just the kind of place you?d expect lots of healthy food and fresh vegetables served within a couple of days of harvest, right? Sure, if you?re ordering ...

MTV.com
If You Never Played ?Skate,? Should You Care About ?Skate 2′?
MTV.com -
Oh, and in case you were wondering, you can (finally) be a female skater. As for me, despite having passed on ?Skate,? my limited time with the sequel has ...
Why Do You Play Fantasy Baseball?
SportingNews.com -
I am here to tell you that fantasy baseball is much more than just names and numbers, and if played the right way, fantasy baseball is a highly beatable ...
Source: Google News

Nutrition Intervention Trials in Linxian, China: Supplementation With Specific Vitamin/Mineral … -
WJ Blot, JY Li, PR Taylor, W Guo, S Dawsey, GQ … - jnci, 1993 - jnci.oxfordjournals.org
METHODS: Individuals of ages 40?69 were recruited in 1985 from four Linxian
communes. Mortality and cancer incidence during March 1986-May 1991 were
ascertained for 29584 adults who received daily vitamin and mineral ...

Cell Growth Arrest and Induction of Cyclin-Dependent Kinase Inhibitor p21WAF1/CIP1 Mediated by STAT1 -
YE Chin, M Kitagawa, WCS Su, ZH You, Y Iwamoto, XY … - Science, 1996 - sciencemag.org
Signal transducers and activators of transcription (STAT) proteins can be
conditionally activated in response to epidermal growth factor (EGF) and
interferon (IFN)- . STAT activation was correlated with cell growth ...

Nonlocal Boundary Layer Vertical Diffusion in a Medium-Range Forecast Model -
SY Hong, HL Pan - Monthly Weather Review, 1996 - ams.allenpress.com
In this paper, the incorporation of a simple atmospheric boundary layer
diffusion scheme into the NCEP Medium-Range Forecast Model is described. A
boundary layer diffusion package based on the Troen and Mahrt nonlocal ...

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and bold beta APP processing -
G Yu, M Nishimura, S Arawaka, D Levitan, L Zhang, … - Nature, 2000 - nature.com
Nicastrin, a transmembrane glycoprotein, forms high molecular weight complexes
with presenilin 1 and presenilin 2. Suppression of nicastrin expression in
Caenorhabditis elegans embryos induces a subset of notch/glp-1 phenotypes ...

Activation of the I?B Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme … -
… E Spencer, L Yang, A Braun, J You, C Slaughter, C … - Cell, 2000 - Elsevier
TRAF6 is a signal transducer in the NF-?B pathway that activates I?B kinase
(IKK) in response to proinflammatory cytokines. We have purified a heterodimeric
protein complex that links TRAF6 to IKK activation. Peptide mass ...

Control of Memory Formation Through Regulated Expression of a CaMKII Transgene -
M Mayford, ME Bach, YY Huang, L Wang, RD Hawkins, … - Science, 1996 - sciencemag.org
One of the major limitations in the use of genetically modified mice for
studying cognitive functions is the lack of regional and temporal control of
gene function. To overcome these limitations, a forebrain-specific promoter ...

Present-Day Crustal Deformation in China Constrained by Global Positioning System Measurements -
… , R Bilham, KM Larson, X Lai, X You, Z Niu, J Wu, … - Science, 2001 - sciencemag.org
Global Positioning System (GPS) measurements in China indicate that crustal
shortening accommodates most of India's penetration into Eurasia. Deformation
within the Tibetan Plateau and its margins, the Himalaya, the Altyn Tagh, ...

Expression cloning of a mammalian proton-coupled oligopeptide transporter -
YJ Fei, Y Kanai, S Nussberger, V Ganapathy, FH … - Nature, 1994 - palgrave-journals.com
* Renal Division, Department of Medicine, Brigham and Women's Hospital and
Harvard Medical School and Department of Biological Chemistry and Molecular
Pharmacology, Harvard Medical School, 75 Francis Street, Boston, ...

Hepatitis Be Antigen and the Risk of Hepatocellular Carcinoma -
HI Yang, SN Lu, YF Liaw, SL You, CA Sun, LY Wang, … - New England Journal of Medicine, 2002 - content.nejm.org
Methods In 1991 and 1992, we enrolled 11,893 men without evidence of
hepatocellular carcinoma (age range, 30 to 65 years) from seven townships in
Taiwan. Serum samples obtained at the time of enrollment were tested for ...

Ubiquitination of hypoxia-inducible factor requires direct binding to the bold beta-domain of the … -
M Ohh, CW Park, M Ivan, MA Hoffman, TY Kim, LE … - Nature Cell Biology, 2000 - nature.com
Results pVHL binds to a region of HIF implicated in oxygen-dependent
protoeolysis. To determine the structural requirements for binding of pVHL to
HIF, we fused various fragments of HIF1 to the Gal4 DNA-binding domain, ...

Source: Google Scholar
 
 

Churchgoes Breathe Easier
Article Date: 02 Dec 2006 - 12:00pm (PST)

Going to church might help you breathe easier. A new study by Temple University's Joanna Maselko, Sc.D., found that religious activity may protect and maintain pulmonary health in the elderly.

"Pulmonary function is an important indicator of respiratory and overall health, yet little is known about the psychosocial factors that might predict pulmonary function. At the same time, religious activity is emerging as a potential health promoting factor, especially among the elderly. We wanted to determine whether there was a connection between the two," Maselko said.

"Religious Service Attendance and Decline in Pulmonary Function in a High-Functioning Elderly Cohort," published in the November 2006 issue of the Annals of Behavioral Medicine, was conducted while Maselko, assistant professor of public health, was at Harvard University.

Using peak expiratory flow rate (PEFR), researchers measured pulmonary function in 1,189 study subjects ranging in age from 70 to 79 years. They found that regular religious service attendance (at least weekly attendance) was associated with a slower pulmonary function decline among men and women, compared to those who never attend services. The findings could not be explained by differences in smoking or physical activity.

Maselko and her colleagues believe that this is the first study to examine the relationship between religious engagement and lung function over time. Religious activity could benefit health in a number of ways. Overall, going to church provides social contact and emotional support, thereby reducing the isolation that afflicts many elderly and boosting psychological well-being.

The researchers recommend that future research look at congregation specific benefits, as the current study focused on Christian religious services. Maselko, a social epidemiologist and an expert in religion-health research, is currently looking at the relationship between spiritual coping and mental and physical health among individuals in India who are predominantly Hindu.

###

Co-authors of the study were Laura Kubzansky, Ph.D., and Ichiro Kawachi, M.D., Ph.D., Department of Society, Human Development and Health, Harvard School of Public Health; John Staudenmayer, Ph.D., Department of Mathematics and Statistics, University of Massachusetts, Amherst; Lisa Berkman, Ph.D., Department of Society, Human Development and Health, Harvard School of Public Health.

Contact: Eryn Jelesiewicz
Temple University

Article continues below and (thank you)
 

Fatigue Reduced In Auto-Immune Conditions By Low Impact Aerobic Exercise Says Multi-study Review

Low impact aerobic exercise, such as walking and cycling, can effectively reduce fatigue in adults with chronic auto-immune conditions, according to a research review in the latest issue of the UK-based Journal of Advanced Nursing.

A team led by nurse researcher Dr Jane Neill from Flinders University in Adelaide, examined 162 research studies published between 1987 and 2006, analysing 36 in detail.

They discovered that there was evidence that people with conditions like multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus could benefit from exercise that gradually increased in intensity, duration and frequency.

"Fatigue is a major symptom in all three conditions and can cause a range of physical, psychological and social problems" says Dr Neill.

"Our review showed that aerobic exercise can significantly reduce fatigue and that some behavioural, nutritional and physiological interventions are also very effective."

Studies reviewed by the team tested 38 interventions on more than 1,700 patients. 24 resulted in statistically reduced fatigue or increased vitality levels.

The effective aerobic exercise programmes lasted an average of 12 weeks, with participants exercising for 30 to 60 minutes, three times a week.

Group interventions involved supervised exercise classes, including warm up, low impact aerobic activity and strengthening or stretching exercises before cool down.

Home-based programmes made use of exercise bicycles, walking, cycling, jogging or swimming.

"There is good evidence that people experiencing fatigue from chronic auto-immune conditions can benefit from a range of non-medicinal interventions" concludes Dr Neill.

"Other effective strategies, apart from aerobic exercise, include health education and cognitive behavioural therapy."

"Cooling techniques and nutritional supplements such as acetyl-L-carnitine and fish oil showed a number of benefits, but need to be looked at in more detail."

The authors suggest electro-magnetic field devices also warrant further investigation, due to promising results.

But they add that low-cost, low technology interventions that promote self-management of fatigue are probably more appropriate and feasible than those requiring specialised equipment or professional expertise.

They stress that any exercise programmes must be suitable for each individual and take account of issues that affect how people manage their conditions, like reduced mobility, pain, nausea and stress.

"Healthcare professionals should ask people about their fatigue and assess each person's symptoms" adds Dr Neill. "People with fatigue should be encouraged to design their own exercise routines based on awareness of their individual fatigue patterns and daily priorities, while group activities must take account of the changing nature of fatigue over time."

Previous research suggests that 70 per cent of people with multiple sclerosis suffer daily fatigue, 57 per cent of people with rheumatoid arthritis experience fatigue and 81 per cent of those with system lupus erythematosus find fatigue moderately to severely disabling.

"Any measures that can reduce people's fatigue and improve their quality of life are to be welcomed. Our review shows that some interventions have great potential, particularly in the short term, but that more research is needed to measure their long-term effectiveness" says Dr Neill.

###

* Effectiveness of non-pharmacological interventions for fatigue in adults with multiple sclerosis, rheumatoid arthritis or systemic lupus erythematosus: a systematic review. Neill J, Belan I and Ried K. Journal of Advanced Nursing. Volume 56.6, pages 617-635.

* Journal of Advanced Nursing, which is celebrating its 30th anniversary in 2006, is read by experienced nurses, midwives, health visitors and advanced nursing students in over 80 countries. It informs, educates, explores, debates and challenges the foundations of nursing health care knowledge and practice worldwide. Edited by Professor Alison Tierney, it is published 24 times a year by Blackwell Publishing Ltd, part of the international Blackwell Publishing group. http://www.journalofadvancednursing.com/

Contact: Annette Whibley
Blackwell Publishing Ltd.
 

New Hope For Children With Wilms' Tumour

Scientists at The Institute of Cancer Research have made a significant breakthrough in predicting the behaviour of Wilms' tumour (a type of childhood kidney cancer). For children with the aggressive form of the disease, who have a lower chance of survival, this research offers new hope through the possibility of targeted treatments. The publication coincides with the launch of Childhood Cancer Awareness Month.

In the UK around 70 children are diagnosed with Wilms' tumour each year - the fifth most common childhood cancer. The majority of these children have a good chance of survival following standard treatment. However, around 15% have a form of the disease which is more prone to return and have only a 50% chance of survival. At present it is not possible to predict whether a child's cancer is likely to relapse or not.

The research by scientists at The Institute of Cancer Research, funded by Cancer Research UK, has been published in the journal Cancer Research*. Using DNA microarrays, which allow the measurement of thousands of genes at the same time, the scientists found a significant link between an increased number of copies of the IGF1R gene and an increased risk of treatment failure and relapse.

The IGF1R gene codes for the IGF1R protein, a cell surface receptor that plays a key role in cell growth and division. The scientists found that children with more copies of the IGF1R gene have a greater number of these receptors on the surface of their cancer cells. It is hoped that this development will provide a new target for treating children with this aggressive form of Wilms' tumour.

Lead investigator, Dr Chris Jones, Team Leader in Paediatric Molecular Pathology at The Institute of Cancer Research said:

"These early results represent a significant development in our understanding of why some Wilms' tumours may be resistant to conventional treatment. They are particularly exciting as we have identified a defect for which there are already new drugs entering clinical trials."

Professor John Toy, medical director of Cancer Research UK, said:

"This research finding of subtle genetic differences within the same type of cancer may help in identifying which Wilms' tumours are likely to respond less well to treatment. It may, therefore, one day lead to new and different, more successful options for treating children with this particular sub-type of the disease."

###

* Cancer Research issue 66 volume 23

Childhood Cancer Awareness Month runs from 1st - 31st December 2006

The results are based on a study of 68 Wilms' tumour samples

Contact: Nadia Ramsey

The Institute of Cancer Research

The Institute of Cancer Research is Europe's leading cancer research centre with expert scientists working on cutting edge research. It was founded in 1909 to carry out research into the causes of cancer and to develop new strategies for its prevention, diagnosis, treatment and care. Website at http://www.icr.ac.uk.

The Institute works in a unique partnership with The Royal Marsden NHS Foundation Trust, forming the largest Comprehensive Cancer Centre in Europe. This relationship enables close daily contact with those on the frontline in the fight against cancer - the clinicians, the carers and most importantly, the patients.

The Institute is a charity that relies on voluntary income. The Institute is one of the world's most cost-effective major cancer research organisations with over 90p in every £ directly supporting research.

About Cancer Research UK

Together with its partners and supporters, Cancer Research UK's vision is to beat cancer.
  • Cancer Research UK carries out world-class research to improve understanding of the disease and find out how to prevent, diagnose and treat different kinds of cancer.
  • Cancer Research UK ensures that its findings are used to improve the lives of all cancer patients.
  • Cancer Research UK helps people to understand cancer, the progress that is being made and the choices each person can make.
  • Cancer Research UK works in partnership with others to achieve the greatest impact in the global fight against cancer.
For further information about Cancer Research UK's work or to find out how to support the charity, please visit Cancer Research UK.

Source:
The Institute of Cancer Research
 
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