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Recent News and Articles on the Keywords: web + 0.30  Related to the article below (Last Update: 8/4/2008)

begins at: 10:15 PM ET
USA Today -
While Jurrjens has struggled to find success lately, he has still been outstanding on the road, posting a 0.30 ERA in winning his last four away from Turner ...
Endeavour Announces Record Revenues and Cash Flow
MarketWatch - 16 minutes ago
Endeavour will host a conference call and web cast tomorrow to discuss 2008 second quarter financial and operational results at 9:00 am Central Daylight ...WAR:CFL - END
Puget Energy Reports Second Quarter 2008 Financial Results
WELT ONLINE, Germany -
11, 2008, a copy of which will be available through the SEC?s Web site at www.sec.gov or at www.pugetenergy.com. Investors are encouraged to read the ...PSD
Lydall Announces Financial Results for the Second Quarter and Six ...
CNNMoney.com -
The call may be accessed in a listen-only mode at 877-440-5804 and will be webcast live on the Company's web site www.lydall.com under the Investor ...LDL
Royal Gold to Acquire Barrick Gold's Royalty Portfolio
Your Metal News (press release), UK - Aug 1, 2008
Royal Gold currently owns an additional 0.30%-1.50% sliding-scale NSR royalty on the property. This acquisition consolidates the Mulatos royalty and ...ABX - RGLD
Actel Announces Second Quarter 2008 Financial Results
CNNMoney.com - Jul 29, 2008
A live web cast and replay of the call will be available. Web cast and replay access information as well as financial and other statistical information can ...ACTL
Mexico?s inflation accelerates more than forecast
Tehran Times, Iran - Jul 25, 2008
?If inflation expectations deteriorate, we?ll see a hike in August,? said Casillas, the only analyst in the survey to forecast inflation above 0.30 percent. ...
Japan stocks likely range-bound amid econ worries
Forbes, NY -
... new supply Platinum falls nearly 6 pct on fears over car demand Oil falls to 3-month low as OPEC output rises STOCKS TO WATCH -- Rakuten Inc Web ...
First Stump Delivery Arrives on Schedule
FOXBusiness - Aug 1, 2008
CONTACT INFORMATION Corporate Inquiries: Kevin Hull or Alan Campbell (604) 685-2222 Email: Email Contact Or visit Klondike Silver's web-site: ...CVE:KS - PINK:KLSVF - TSE:X

CPI Financial
Peapack-Gladstone Financial Corporation Reports 27% Increase in ...
MarketWatch - Aug 1, 2008
To learn more about Peapack-Gladstone Financial Corporation and its services please visit our web site at www.pgbank.com or call 908-234-0700. ...
Bluegreen Corporation Reports 2008 Second Quarter Financial Results WELT ONLINE
ADP Reports Fiscal 2008 Results; Provides Fiscal 2009 Guidance Trading Markets (press release)
State Bancorp, Inc. Reports Second Quarter Earnings and Declares ... CNNMoney.com (press release)
MarketWatch - MarketWatch
all 977 news articles »  ADP - BANR - PGC
Source: Google News

Measuring the Independence of Central Banks and Its Effect on Policy Outcomes -
A Cukierman, SB Web, B Neyapti - The World Bank Economic Review, 1992 - World Bank
... Legal central bank in- depen- dence" (index) 0.33 0.33 0.31 0.30 0.30 0.30 0.29
0.29 0.27 0.27 0.27 0.27 0.25 0.24 0.24 0.22 0.21 0.21 0.21 0.20 0.20 0.18 0.17 ...

… This article has been selected for the open discussion forum on the STS Web site: http://www. sts. … -
A Yamaguchi, T Ino, H Adachi, S Murata, H Kamio, M … - The Annals of Thoracic Surgery, 1998 - Soc Thorac Surgeons
... ctsnetjournals.org/cgi/content/full/65/2/434 the World Wide Web at: The ... heart failure
in 41 patients with a preoperative ejection fraction of less than 0.30. ...

Creating Adaptive Web Sites Through Usage-Based Clustering of URLs -
B Mobasher, R Cooley, J Srivastava - Proceedings of the 1999 Workshop on Knowledge and Data …, 1999 - doi.ieeecs.org
... We used the access logs from the University of Minnesota Computer Science Web server
to evaluate ... A cut-off value of 0.30 was used for the recommendation score. ...

The Hidden Web -
HA Kautz, B Selman, MA Shah - AI Magazine, 1997 - cs.rochester.edu
... Before presenting the REFERRAL WEB system in more detail, let us first evaluate
the feasi- bility of any approach to automating ... 1.00 0.30 0.1 377.2 94.6 ...

Temperature controlled method of coating a paper web -
S Saji, Y Tanaka, K Yokota, M Yamamoto - US Patent 5,032,225, 1991 - freepatentsonline.com
... What is claimed is: 1. A method of making a coated paper by coating on a paper machine
a paper web having a wet value of -0.30 to +0.20 g by weight, in which ...

Effect of a platelet activating factor antagonist, WEB 2086, on allergen induced asthmatic responses -
A Freitag, RM Watson, G Matsos, C Eastwood, PM O' … - British Medical Journal, 1993 - thorax.bmj.com
... The log difference (before and after allergen) in histamine PC20 was 0.35
(0.06) after placebo treatment and 0.30 (0.1) after WEB 2086. ...

[PS] On the Implications of Zipf?s Law for Web Caching -
L Breslau, P Cao, L Fan, G Phillips, S Shenker - 3rd International WWW Caching Workshop, 1998 - linofee.org
... Once again the model predicted by Zipf?s law is consistent with data observed at
operational web servers [RV98, CI97], that is, the probability that a ... 0.30 ...

Silk from a sow's ear: extracting usable structures from the Web -
P Pirolli, J Pitkow, R Rao - Proceedings of the SIGCHI conference on Human factors in …, 1996 - portal.acm.org
... Home Page + + + + 0.30 Personal Home > 1 k & < 3 - - 0.51 Page k Content ... the ripper",
was used to extract characteristics directly from the Web server's file ...

Curriculum Sequencing in a Web-Based Tutor -
MK Stern, BP Woolf - Intelligence Tutoring System (Proc. 4th Int'l Conf. ITS'98) - Springer
... Curriculum Sequencing in a Web-Based Tutor 579 ... Equation Used Quizzed Studied Reviewed
Total 1 5 0.90 0.90 0.10 0.90 2 4 0.50 0.80 0.70 0.605 3 4 0.30 0.40 0.15 ...

Developing and validating an instrument for measuring user-perceived web quality -
AM Aladwani, PC Palvia - Information & Management, 2002 - Elsevier
... correlated significantly with users? overall quality rating for the web site; the ...
between OQR and specific content was the lowest (Pearson?s r=0.30). ...

Source: Google Scholar
 
 

More Insight Into Alzheimer's Disease With Stanford Discovery Of Possible Cause

Article Date: 26 Nov 2006 - 18:00pm (PST)
A peacekeeper in the body's defenses against infection may hold the key to understanding - and eventually treating - Alzheimer's disease. Researchers at the Stanford University School of Medicine discovered that when a molecule responsible for dialing down the immune system malfunctions in the brain cells of mice, the rodents develop symptoms of the degenerative brain disease.

The finding, published in the November issue of the Journal of Clinical Investigation, offers researchers an insight into how humans may develop Alzheimer's, said the study's senior author Tony Wyss-Coray, PhD, associate professor of neurology and a researcher at the Veterans Affairs Palo Alto Health Care System.

Alzheimer's disease is characterized by an excessive buildup of proteins into plaques and tangles of cellular gunk that are likely to cause brain cells to die and lose their connections to other neurons. But for the most part, scientists do not understand the underlying biological problems behind Alzheimer's, making it difficult for doctors to treat, let alone cure.

Article continues below and (thank you)
 
"We don't have a treatment that alters the course of the disease," said Wyss-Coray.

Wyss-Coray and Ina Tesseur, PhD, an instructor in the Department of Neurology, examined thin slices of the brains of Alzheimer's patients who had died, and discovered abnormally low levels of a molecule involved in controlling the body's response to infection. That molecule allows the brain to detect and respond to TGF-beta, or transforming growth factor, a protein teeming through our bodies, involved in fighting infection, stopping cancer and perhaps keeping brain cells alive.

No other researchers had seen this change before, so Tesseur and Wyss-Coray set out to investigate whether it had some connection to Alzheimer's disease. They hypothesized that by protecting neurons, TGF-beta may help prevent Alzheimer's disease. If the TGF-beta pathway is turned off, the brain becomes more susceptible to a toxic buildup of proteins.

"We tried to see what happens if we block neurons from getting this beneficial signal," said Wyss-Coray.

To investigate that hypothesis, the researchers genetically engineered mice with a defect similar to the one they found in the brains of Alzheimer's patients: These mice had brain cells that could no longer respond to TGF-beta's salutary signal.
 
The mutation did not directly affect the TGF-beta protein, which is found throughout the body. Instead, it blocked brain cells' ability to detect and respond to the molecule. This way, the TGF-beta pathway was active everywhere else besides the neurons of the mice.

Unable to receive the beneficial TGF-beta signal, the rodents with the broken pathway showed signs of Alzheimer's disease. Brain cells died as the mice grew older, and the cells failed to make connections to other brain cells, a defining trait of the cells.

The results were even more striking when the researchers blocked the TGF-beta pathway in mice that were already susceptible to an Alzheimer's-like disease. These mice had a rare version of a human gene that causes people to develop Alzheimer's in their 40s and 50s, said Wyss-Coray. Blocking TGF-beta in these mice caused the animals to display signs of Alzheimer's disease that researchers had until then failed to recreate. The brains of the mice had more dead cells and a protein buildup characteristic of the disease in humans.

"Our study offers the possibility that if you have a reduction in this pathway, then you can accelerate the pathology," said Wyss-Coray. The flip side is that activating the TGF-beta pathway may offer a treatment for Alzheimer's, he said.

In the past, researchers have tried using molecules that work like TGF-beta to provide protection against Alzheimer's, but they had trouble getting them into the brain, said Wyss-Coray. Those proteins, or the cells used to carry them, are too large to enter the brain through the bloodstream.

To sidestep that problem, Wyss-Coray is working with chemists to identify small molecules - drugs - that can boost the TGF-beta pathway in neurons. Because of TGF-beta's many roles in the body, Wyss-Coray will also be searching for molecules that act only on brain cells. He will test whether these drugs can ameliorate the Alzheimer's-like disease he created in mice.

Wyss-Coray said that for now the strategy is "wishful thinking," but based on the results of this study, it's worth trying.

###

Co-authors of the study included Kun Zou, PhD; Elisabeth Berber, PhD; Judith Van Can, and Amy Lin, PhD, who all were involved in the research while at the medical school's Department of Neurology. The John Douglas French Alzheimer's Foundation, the Alzheimer's Association and the National Institutes of Health funded the research.

Stanford University Medical Center integrates research, medical education and patient care at its three institutions - Stanford University School of Medicine, Stanford Hospital & Clinics and Lucile Packard Children's Hospital at Stanford. For more information, please visit the Web site of the medical center's Office of Communication & Public Affairs at http://mednews.stanford.edu/.

Contact: Rosanne Spector
Stanford University Medical Center
 
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