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Recent News and Articles on the Keywords: web + 0.14  Related to the article below (Last Update: 8/4/2008)


Earthtimes (press release)
Web.com Reports Second Quarter 2008 Financial Results
istockAnalyst.com, OR -
"Despite challenging economic conditions, Web.com was able to hit the top of its quarterly revenue and earnings guidance. The operating leverage potential ...
athenahealth, Inc. Reports Second Quarter 2008 Results WELT ONLINE
Actuate Reports Second Quarter 2008 Financial Results MarketWatch
Sonic Foundry Reports Third Quarter 2008 Results IT News Online
Trading Markets (press release) - PR Newswire (press release)
all 672 news articles »  ACTU - ATHN - THOR

ZDNet
How I Learned to Stop Worrying and Love Windows Vista. NOT!
ZDNet -
Granted, her older box used Firefox 2.0.0.14 and the new one 3.0, but when I regression tested 3.0 as the default browser on my own XP systems and with the ...
Triad Guaranty Inc. Reports Second Quarter Loss as Reported ...
MarketWatch -
For more information, please visit the Company's web site at www.triadguaranty.com. Diluted realized investment gains (losses) per share, net of taxes, ...TGIC
Boots & Coots Reports Second Quarter and Six Month Results
MarketWatch -
... to these forward-looking statements are found in Boots & Coots' SEC filings, which are available free of charge on the SEC's web site at www.sec.gov. ...WEL
Six Flags Announces Second Quarter Results
CNNMoney.com (press release) -
The teleconference will be broadcast live to all interested persons as a listen-only Web cast on http://investors.sixflags.com/. The Web cast will be ...SIX
TheStreet.com Reports Second-Quarter Financial Results
MarketWatch - Jul 31, 2008
It engages audiences on video and digital platforms through some of the Web's best known sites: TheStreet.com, RealMoney.com, Stockpickr.com, ...
ScottsMiracle-Gro Announces Record Third Quarter Sales Based on ... PR Newswire (press release)
LoopNet, Inc. Announces Second Quarter 2008 Financial Results Trading Markets (press release)
all 475 news articles »  TSCM - LOOP - SMG

CPI Financial
ADP Reports Fiscal 2008 Results; Provides Fiscal 2009 Guidance
Trading Markets (press release), CA - Jul 31, 2008
ADP's news releases, current financial information, SEC filings and Investor Relations presentations are accessible at the same Web site. ...
Beasley Broadcast Group Reports Second Quarter Revenue of $31.0 ... Primenewswire (press release)
Chicopee Bancorp, Inc. Reports Second Quarter Results FOXBusiness
Cascade Microtech Reports Second Quarter 2008 Results Trading Markets (press release)
all 1,014 news articles »  ADP - BBGI - CSCD

WELT ONLINE
Susquehanna Bancshares, Inc. Announces Second Quarter Results
WELT ONLINE, Germany - Jul 23, 2008
Net charge-offs as a percentage of average loans and leases for the quarter ended June 30, 2008 were 0.48% compared to 0.14% for the second quarter of 2007. ...
First Security Group Announces Earnings MarketWatch
West Coast Bancorp Reports 2008 Second Quarter Earnings Earthtimes (press release)
Tower Financial Corporation Reports Earnings of $0.08 Per Share Primenewswire (press release)
MarketWatch - MarketWatch
all 1,034 news articles »  TOFC - SNV - SUSQ
Nexity Financial Second Quarter Results
Trading Markets (press release), CA - Jul 31, 2008
Webcast: Live via the Internet and Windows Media Player http://www.nexitybank.com/ then to the Investor Relations section, to conference in via the web Then ...NXTY
NMS Communications Announces Financial Results for the Second ...
Business Wire (press release), CA - Jul 31, 2008
Non-GAAP loss from continuing operations was $(6.3) million, or $(0.14) per share, for the second quarter of 2008, compared to a non-GAAP loss from ...NMSS
Source: Google News

Measuring the Independence of Central Banks and Its Effect on Policy Outcomes -
A Cukierman, SB Web, B Neyapti - The World Bank Economic Review, 1992 - World Bank
... bank in- depen- dence" (index) 0.33 0.33 0.31 0.30 0.30 0.30 0.29 0.29 0.27 0.27
0.27 0.27 0.25 0.24 0.24 0.22 0.21 0.21 0.21 0.20 0.20 0.18 0.17 0.14 0.10 ...

[PDF] Data Preparation for Mining World Wide Web Browsing Patterns -
R Cooley, B Mobasher, J Srivastava? - Knowledge and Information Systems, 1999 - mis.ncyu.edu.tw
Page 1. Data Preparation for Mining World Wide Web Browsing Patterns ... An important
input to these design tasks is the analysis of how a Web site is being used. ...

Measuring web site quality improvements: a case study of the forum on strategic management knowledge … -
SJ Barnes, R Vidgen - Industrial Management & Data Systems, 2003 - emeraldinsight.com
... [ 302 ] Stuart J. Barnes and Richard Vidgen Measuring Web site quality improvements:
a case study of the forum on strategic management knowledge exchange ... 0.14 ...

… of silver carp Hypophthalmichthys molitrix Val. and its impact on the food web in Lake Kinneret, … -
P Spataru, M Gophen - Hydrobiologia, 1985 - Springer
... and its impact on the food web in Lake Kinneret, Israel ... 2 0.37 0.04 0.71 3 1 .05
11 14.04 3 1 .42 0.14 0.26 5 0.35 3 8 .14 4 0.11 0.01 0.01 0.14 0 0 0.15 ...

Classification of Web documents using a naive Bayes method -
Y Wang, J Hodges, B Tang - Tools with Artificial Intelligence, 2003. Proceedings. 15th …, 2003 - ieeexplore.ieee.org
... For example, in [13], the total number of categories used by Quek?s web document
classification ... MB MN MB MN MB MN 0 0.14 0.14 1 1 0.25 0.25 0.1 0.17 0.3 0.87 ...

Harvesting implicit group attitudes and beliefs from a demonstration web site -
BA Nosek, MR Banaji, AG Greenwald - Group Dynamics: Theory, Research, and Practice, 2002 - content.apa.org
... 63 ms (d 0.28); conservative set: face 26 ms (d 0.12), name 29 ms (d 0.14). ... Explicit
Attitudes for Each of the Nine Tasks Available at the IAT Web Site Between ...

Real life information retrieval: a study of user queries on the Web -
BJ Jansen, A Spink, J Bateman, T Saracevic - ACM SIGIR Forum, 1998 - portal.acm.org
... But in any case, this, of course, has interesting implications for recall and may
illustrate a need for high precision in Web IR algorithms ... 15 25 0.14 50 2 0.01 ...

[PDF] An Adaptive Agent for Web Exploration Based on Concept Hierarchies -
S Parent, B Mobasher, S Lytinen - Proceedings of the 9th International Conference on Human …, 2001 - maya.cs.depaul.edu
... On the other hand, a user interested in searching the Web for specific medical ... music:
1.000 blue: 0.15 new: 0.14 artist: 0.13 jazz: 0.12 review: 0.12 band ...

The influence of browsers on evaluators or, continuations to program web servers -
C Queinnec - Proceedings of the fifth ACM SIGPLAN international …, 2000 - portal.acm.org
... 2.3 Web computation q? !vG?$? ?2" ? 4&s?$&? cf ???X 7 G !vH cf ? ?g ... If
1 FRF corresponds to 0.14 $ then 3 FRF corresponds to 0.42 $. ...

[PDF] Phylogenetic constraints and adaptation explain food-web structure -
MF Cattin, LF Bersier, C Banasek-Richter, R … - Nature, 2004 - unifr.ch
... by one order of magnitude?in the prediction of these standard food-web descriptors. ...
T 0.06 [0.04] 0.08 0.05 [0] 0.03 0.10 [0] 0.10 0.14 [0.28] 0.15 0.08 [0.38 ...
-

Source: Google Scholar
 
 

Anti-cancer Drug Shows Early Promise In Pulmonary Hypertension

Article Date: 19 Nov 2006 - 20:00pm (PST)
A drug used to treat kidney cancer can prevent the development of pulmonary hypertension (high blood pressure in the lungs) in rodents, report researchers from the University of Chicago at the 2006 annual meeting of the American Heart Association, Nov. 12-15 in Chicago. There is no curative therapy for this condition.

"We are excited about this finding because there are so few treatment options for pulmonary hypertension," said study author Mardi Gomberg-Maitland, M.D., M.Sc., assistant professor of medicine at the University of Chicago. "We have drugs that can slow progression of the disease but nothing that can stop or reverse the process. This is a ray of hope."

Pulmonary hypertension and cancer share certain features. Both diseases involve abnormal cellular growth. These abnormal cells - in the case of pulmonary hypertension, those that line the blood vessels leading to the lungs - release signals that stimulate the growth of small new blood vessels to feed the renegade cells, allowing further proliferation, and thickening of the vessel walls. Sorafenib appears to interfere with that process.

Article continues below and (thank you)

 
Although originally designed to fight colon cancer, the drug, sorafenib (Nexavar®), proved much more effective against kidney cancer. Sorafenib inhibits an enzyme, known as Raf kinase, which plays a role in tumor-cell growth. Researchers eventually realized it also hit other targets. After clinical trials in kidney cancer patients demonstrated improved survival, it won FDA approval in December 2005.

Now, in a surprise finding, it appears to have a use in treating this cardiovascular disease.

In pulmonary hypertension, the vessels that carry blood from the heart to the lungs constrict. Their walls thicken, which narrows the opening and reduces blood flow. Pressures within the arteries build up, requiring the heart to pump harder to push blood through the narrowed tubes to the lungs. Eventually the heart can no longer keep up. Less and less blood reaches the lungs, the heart enlarges to try to overcome the pressure, and damage to the overworked heart accumulates.
 
Although treatment for pulmonary hypertension has improved, long-term survival, even with therapy, is disappointing, similar to that for lung cancer. Because sorafenib inhibits the chemical signals that can trigger both cellular proliferation and new blood vessel growth, Gomberg-Maitland and colleagues suspected it might slow the growth and thickening of the pulmonary artery walls.

To test this theory they treated rats at high risk for pulmonary hypertension with sorafenib. The researchers studied five groups of rats. One group stayed in normal cages and received no medication. The other four groups spent three weeks in a low-oxygen environment - about half the normal level - which can trigger pulmonary hypertension. Rats in the reduced-oxygen chambers received: no medication, a drug called SU5416 (well known to cause severe pulmonary hypertension in this setting), SU5416 plus sorafenib, or sorafenib alone.

As expected, the unmedicated rats in a low-oxygen environment had mildly elevated pulmonary artery pressures after three weeks and those that received SU5416 developed severe pulmonary hypertension. But, those that received sorafenib or sorafenib plus S5416, had negligible pressure increases. Sorafenib appeared not only to counteract the effects of the low-oxygen environment but also to prevent the additional damage caused by SU5416.

"This was an encouraging sign," said Gomberg-Maitland. This is "one of the best models we have for this disease," she said.

The side effects of the drug in humans have been relatively mild. The most common adverse effects are: rashes of the face and arms or hands and feet, mild diarrhea, and fatigue.

A phase-1 clinical trial of the drug in human patients with pulmonary hypertension is expected to begin this winter.

###

Contact: John Easton
University of Chicago Medical Center
 
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