Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California

 

Recent News and Articles on the Keywords: 0.15 + web  Related to the article below (Last Update: 8/4/2008)

Salix Pharmaceuticals Reports 2Q2008 Results
FOXBusiness -
Interested parties can access the conference call by way of web cast or telephone. The live web cast will be available at www.salix.com. A replay of the web ...SLXP
Boots & Coots Reports Second Quarter and Six Month Results
MarketWatch -
... to these forward-looking statements are found in Boots & Coots' SEC filings, which are available free of charge on the SEC's web site at www.sec.gov. ...WEL
Anadarko Announces Second-Quarter Results
WELT ONLINE, Germany -
A replay of the call will also be available on the Web site for approximately 30 days following the conference call. ANADARKO OPERATIONS REPORT For more ...APC - BOM:500312 - WAR:CFL
Telecom Italia unveils iPhone pricing plans
Telecom Paper (subscription), Netherlands - Jul 14, 2008
The iPhone customers who sign up to iPhone Web Oversize package can make calls to all landlines and mobiles in Italy for EUR 0.15 per minute and text ...

FLEXNEWS
AGL Resources Reports Second Quarter 2008 Results; Reaffirms ...
Earthtimes (press release), UK - Jul 31, 2008
Reported GAAP diluted earnings per share (EPS) of $(0.15), compared to EPS of $0.40 per diluted share for second quarter 2007 -- Earnings, excluding the ...
The Phoenix Companies, Inc. Second Quarter 2008 Earnings MarketWatch
Acura Pharmaceuticals, Inc. Reports Second Quarter 2008 Financial ... CNNMoney.com (press release)
Kaydon Corporation Reports Second Quarter Results Barron's Blogs
Trading Markets (press release) - Earthtimes (press release)
all 1,227 news articles »  ATG - ACUR - KDN

RTT News
TheStreet.com Reports Second-Quarter Financial Results
MarketWatch - Jul 31, 2008
It engages audiences on video and digital platforms through some of the Web's best known sites: TheStreet.com, RealMoney.com, Stockpickr.com, ...
Omnicare Reports Second Quarter Results Genetic Engineering News (press release)
Shutterfly Announces Second Quarter 2008 Financial Results TMC Net
Sourcefire Announces 2008 Second Quarter Results Trading Markets (press release)
MarketWatch
all 882 news articles »  TSCM - OCR - TSE:XTX

WELT ONLINE
Travelzoo Reports Second Quarter 2008 Results
MarketWatch - Jul 24, 2008
In May 2008, Travelzoo began publishing its Web site and its weekly Top 20(R) list in Spain, after having operated a sales office in Barcelona since ...
Lattice Semiconductor Reports Second Quarter Financial Results CNNMoney.com
Glimcher Reports Second Quarter 2008 Results Earthtimes (press release)
PCTEL Posts $20.3 Million in Second Quarter Revenue from ... Centre Daily Times
MarketWatch
all 773 news articles »  LSCC - CTXS - TZOO
Keynote Reports Fiscal Third Quarter 2008 Results
MarketWatch - Jul 29, 2008
Keynote currently provides its services to 52 percent of the comScore Media Metrix's top 50 Web sites and approximately 45 percent of the Fortune 100 ...KEYN
Kaboose Reports Record Second Quarter 2008 Results with Revenue ...
Canada NewsWire (press release), Canada - Jul 31, 2008
The webcast will be archived on the same web page for 30 days following the live call. The second quarter financial statements and related management's ...TSE:KAB - BOM:532354 - GIS
Ubuntu Security Notice - mozilla-thunderbird, thunderbird ...
Help Net Security, Croatia - Jul 25, 2008
If a user had Javascript enabled and were tricked into opening a malicious web page, an attacker could cause a denial of service via application crash, ...
Source: Google News

Automatic text location in images and video frames -
AK Jain, B Yu - Pattern Recognition, 1998 - doi.ieeecomputersociety.org
... CPU carrier images size ( ) time (s) Advertisement 26 548 769 99.2 0.15 Web
image 54 385 234 97.6 0.11 Color image 30 769 537 72.0 0.40 ...

Late events of translation initiation in bacteria: a kinetic analysis -
W Focuses, NPG Contact - The EMBO Journal, 2000 - nature.com
... GTP hydrolysis was observed due to the uncoupled GTP hydrolysis by IF2 on the ribosomes;
the rate constant of the multiple turnover reaction was 0.15 0.02/s ...

JouleTrack-A Web Based Tool for Software Energy Profiling -
A Sinha, AP Chandrakasan - Proceedings of the 38th Design Automation Conference (DAC … - doi.ieeecomputersociety.org
Page 1. JouleTrack - A Web Based Tool for Software Energy Profiling Amit Sinha Anantha
P. Chandrakasan ... 0 0.05 0.1 0.15 0.2 0.25 Average Current (A) ...

The anatomy of a large-scale hypertextual Web search engine -
S Brin, L Page - Computer Networks and ISDN Systems, 1998 - Elsevier
... Same query repented (IO mostly cached t CPU time (5) 0.09 I .77 0.15 1.31 ... A Web
search engine is a very rich environment for research ideas. ...

[PS] Overview of the TREC-8 Web Track -
D Hawking, E Voorhees, N Craswell, P Bailey - Proc. of TREC-8 - research.microsoft.com
... isw50t .029 0 0.05 0.1 0.15 0.2 0.25 0.3 0.35 0.4 0.45 0.5 0 0.05 0.1 0.15
0.2 0.25 0.3 0.35 0.4 0.45 0.5 Small Web Ad Hoc Figure 3 ...
-

Measuring the Independence of Central Banks and Its Effect on Policy Outcomes -
A Cukierman, SB Web, B Neyapti - The World Bank Economic Review, 1992 - World Bank
... 0.00 2 Policy formulation 0.15 a. Who formulates monetary policy? Bank alone
1.00 ... 1.00 Central bank has no influence 0.00 3 Objectives 0.15 ...

Graph structure in the Web -
A Broder, R Kumar, F Maghoul, P Raghavan, S … - Computer Networks, 2000 - Elsevier
... an URL into an internal id or vice versa, and then only 0.15 ?s/link ... manner, but
is subject to various rules designed to avoid overloading Web servers, avoid ...

Finding information on the World Wide Web: the retrieval effectiveness of search engines -
M Gordon, P Pathak - Information Processing and Management, 1999 - Elsevier
Page 1. Finding information on the World Wide Web: ... Abstract Search engines
are essential for ?nding information on the World Wide Web. ...

Cost estimation for web applications -
M Ruhe, R Jeffery, I Wieczorek - Software Engineering, 2003. Proceedings. 25th International …, 2003 - ieeexplore.ieee.org
... revealed thirty-five potential cost factors in the area of web development, some ...
Novelty of Requirements 0.10 0.15 0.11 Importance of SW Maintenance 0.19 0.24 ...

Stable isotope food web studies: a case for standardized sample treatment -
U Jacob, K Mintenbeck, T Brey, R Knust, K Beyer - Marine Ecology Progress Series, 2005 - esep.de
... Stable isotope food web studies: a case for ... Experimental precision (based on standard
deviation of replicates of a peptone standard) was =0.15? for carbon ...

Source: Google Scholar
 
 

Apollo Life Science's Human Proteins Lead To Improved Cancer Treatment By Boosting Stem Cell Growth

Article Date: 17 Nov 2006 - 0:00am (PST)
Apollo Life Sciences Ltd (ASX: AOP) announced today that initial studies showed two of its human proteins outperform competitor proteins in stimulating faster growth in numbers of blood-producing stem cells, which are mainly used to generate white blood cells for chemotherapy patients.

"This means that Apollo's proteins potentially offer cancer patients the chance to increase their rate of chemotherapy, leading to improved and even lifesaving outcomes," Dr Greg Russell-Jones, Apollo's Science Director, said.

A new study undertaken by Apollo showed that two of its human proteins (hcx(TM)) are up to 53% more effective than similar proteins which competitors produce from non-human cells (p-value less than 0.00021). In the series of in vitro experiments, CD34- positive haematopoietic stem cells enriched from umbilical cord blood were cultured with a medium containing Apollo's fully G-CSF and SCF (granulocyte-colony stimulating factor and stem cell factor) with the same proteins produced from bacteria by competitors. Viable cells were counted at the end of seven days.

Article continues below and (thank you)
 
Because chemotherapy lowers white blood cell counts, patients are susceptible to serious infections. During therapy, delaying the next round of the treatment puts them further at risk. The more quickly proteins can help white blood cells grow back, the quicker that patients may improve.

Apollo's fully human proteins are not derived from animals, yeast or bacteria, unlike most rival products. Therefore Apollo's proteins are likely to behave more accurately in a clinical environment.

Proteins are the basic building blocks of life, controlling diverse processes such as metabolism (energy expenditure), the immune response (involved in fighting diseases), memory in the brain and acting as catalysts for stem cells to produce white blood cells.

Generating large numbers of blood-producing (haematopoietic) stem cells has traditionally used G-CSF (granulocyte-colony stimulating factor) and SCF (stem cell factor). These are types of growth factors, which are naturally occurring proteins that help stimulate cell growth and tell cells what to become - skin cells or organ cells, for example. The market for G-CSF clinical products was estimated at US$4.6 billion in 2005.
 
"This study shows that our G-CSF and SCF, derived from human cells instead of the normal animal, yeast or bacterial cells, used together form a powerful combination for inducing stem cell expansion in vitro," Dr Greg Russell-Jones, Apollo's Science Director, said.

Apollo Life Sciences is the only company in the world producing fully human proteins on such a large scale - it currently offers over 60 for sale.

"Apollo's hcx(TM) proteins are initially being commercialised as materials for researchers. Because they are expressed in human cell lines, they offer the additional advantage that they will not cause cross-species contamination when used to culture adult or embryonic stem cells," said Dr Russell-Jones. "The proteins also have unique potential for clinical therapies where there is a growing preference for eliminating non-human products," said Dr Russell-Jones. "G-CSF is a molecule that has many clinical uses, not only for stem cell expansion, but also for treating chemotherapy-induced neutropenia (low amount of a certain type of white blood cell) and mobilising stem cells into the circulation of transplant donors for collection. Apollo's hcx(TM) cytokines (growth factors) therefore have exciting potential, and this result is just the tip of the iceberg in terms of their clinical usefulness."

"Further studies are under way to elucidate the intracellular pathways mediating this enhanced proliferation, to identify the specific factors that make Apollo's hcx(TM) G-CSF and SCF so unique in mediating stem cell proliferation and differentiation," Dr Russell-Jones added.

About the study

Results were obtained from a series of in vitro experiments using CD34-positive haematopoietic stem cells enriched from umbilical cord blood. Cells were cultured with a medium containing G-CSF and SCF. Viable CD34-positive haematopoietic stem cells were counted after seven days. The tests made direct comparison between Apollo's human-cell expressed (hcx(TM)) G-CSF and SCF, and commercially available G-CSF and SCF expressed in bacterial (E. coli) cells. The combination of Apollo's two hcx(TM) proteins induced up to 53% more cell proliferation compared to the same proteins expressed in bacteria. External statistical analysis showed that the results are highly significant with a p-value less than 0.00021. About Apollo's human cell expressed (hcx(TM)) proteins (www.apollocytokineresearch.com) Apollo has created a library of recombinant human proteins that closely mimic proteins in the human body because they are expressed from human cells (hcx(TM)). Both their amino acid sequence (composition) and post-translational modifications (PTMs or attachments) are human. By contrast, recombinant human proteins available from large competitors are produced from bacteria, yeast or murine cells and consequently lack human attachments.

Research and clinical experience with first-generation biopharmaceuticals are now showing that the human-ness of the attachments in particular is central to how a protein performs its role in the body.

Apollo focuses on ensuring its hcx (TM) proteins are as close to the natural form as possible, without tags, to optimise their usefulness as potential therapeutics, diagnostics and research tools. The company's extensive range of hcx (TM) proteins forms a target-rich bank of candidates that can be selected, refined and developed into biopharmaceuticals to treat a wide range of diseases.

About Apollo Life Sciences Limited

Apollo Life Sciences (ASX: AOP) is a biotechnology company that has made major breakthroughs in the areas of drug delivery and expression of proteins from human cells. Apollo's combined technologies are expected to lead to more effective and lower cost therapeutics, compared to first generation protein-based drugs. For more information visit http://www.apollolifesciences.com.

Apollo Life Sciences Limited
http://www.apollolifesciences.com
 
Google
Web www.iconocast.com
 
 
 

 

Continue News With: News9A ;