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Recent News and Articles on the Keywords: 2006 + web + article  Related to the article below (Last Update: 8/4/2008)

Dell Seeks, May Receive 'Cloud Computing' Trademark
InformationWeek, NY -
By J. Nicholas Hoover Like the term Web 2.0, "cloud computing" is quickly becoming a meme without borders. And like the old one, the new phrase with the ...
Automated Tagging Carries Risk Of Unwanted Results
RedOrbit, TX -
Yahoo already displays its Shortcuts on articles hosted by Yahoo News from sources such as E! Online and Time. And since 2006, The New York Times' Web site ...
Notorious Kirkland troll tells how to avoid his wrath
Seattle Post Intelligencer -
Sunday's New York Times magazine featured one of the most chilling articles I've read on one of the Web's oldest and darkest nuisances - trolls. ...
Going solo? Web site caters to singles
Chicago Tribune, United States - Aug 3, 2008
DePaulo sits on the advisory board for SingleEdition.com, a free Web site and e-mail newsletter that provides lifestyle articles for single adults. ...
With automated tagging, Web links can surprise
The Associated Press - Aug 3, 2008
For example, the word "laptop" in an article could be linked to Best Buy's Web page. For those sites considering expanding their use of the technology, ...
Link by Link An Internal Wiki That?s Not Classified
New York Times, United States -
?A lot of things are not things that you would put on a traditional Web site. If someone directed a desk officer to create an article, it would not be about ...
The Web of Wanton Cruelty As 'Trolling' Turns More Vicious, What ...
RedOrbit, TX -
By Mattathias Schwartz One afternoon in the spring of 2006, for reasons unknown to those who knew him, Mitchell Henderson, a seventh grader from Rochester, ...
Sonnenschein Rebuilds Its IT Data Model
Law.com (subscription), CA -
With a 2006 change in our governance structure, and an explosion of information, we needed quick and easy access to our work-product. ...
World gets hot and bothered
Tampabay.com, FL -
Looking for more reasons to worry? The Web site www.numberwatch.co.uk/warmlist.htm keeps tabs on hundreds of anxiety-inducing articles about the warming world.
The NYT Mag Goes Trolling For Trolls, Finds Something Pretty Nasty
Huffington Post, NY -
What's interesting about these web-themed articles is how they, to borrow a phrase, explode online ? not just in coverage, but in how they are debated and ...NYT
Source: Google News

Complex Trophic Interactions in Deserts: An Empirical Critique of Food-Web Theory -
GA Polis - American Naturalist, 1991 - UChicago Press
... Highlighted Article. Herbivore ... Liang. (2006) Food web of macroinvertebrate community
in a Yangtze shallow lake: trophic basis and pathways. Hydrobiologia ...

THE RISE OF PROFESSIONALISM -
ML Larson - Pediatrics, 1979 - Am Acad Pediatrics
... This information is current as of September 2, 2006 http://www.pediatrics.org the
World Wide Web at: The online version of this article, along with updated ...

Food Web Complexity and Community Dynamics -
GA Polis, DR Strong - American Naturalist, 1996 - UChicago Press
... Highlighted Article. Herbivore-mediated ... Helmut Hillebrand. (2006) Food web complexity
affects stoichiometric and trophic interactions. Oikos 114 ...

A compilation of molecular biology web servers: 2006 update on the Bioinformatics Links Directory -
JA Fox, S McMillan, BF Ouellette - Nucleic Acids Research, 2006 - Oxford Univ Press
... properly cited. Article. A compilation of molecular biology web servers:
2006 update on the Bioinformatics Links Directory. Joanne ...

Community structure in social and biological networks -
M Girvan, MEJ Newman - Proceedings of the National Academy of Sciences, 2002 - National Acad Sciences
... known a collaboration network and a food web and find ... article has been cited by other
articles in HighWire ... system models Brief Bioinform, December 1, 2006; 7(4 ...

Antithrombotic therapy for atrial fibrillation -
GYH Lip, C Boos - British Medical Journal, 2005 - heart.bmj.com
... WEB TOP 10 Heart 2006 92: 528. [Extract] [Full Text]. This article has been cited
by other articles: (Search Google Scholar for Other Citing Articles). ...

… Ischemic Cardiomyopathy This article has been selected for the open discussion forum on the STS Web … -
A Yamaguchi, T Ino, H Adachi, S Murata, H Kamio, M … - The Annals of Thoracic Surgery, 1998 - Soc Thorac Surgeons
... This article has been selected for the open discussion forum on the STS Web site:
http ... at Google Indexer on September 27, 2006 ats.ctsnetjournals.org ...

… Lymph Node Status This article has been selected for the open discussion forum on the STS Web site: … -
TW Rice, G Zuccaro, DJ Adelstein, LA Rybicki, EH … - The Annals of Thoracic Surgery, 1998 - Soc Thorac Surgeons
... This article has been selected for the open discussion forum on the STS Web site:
http ... at Google Indexer on September 1, 2006 ats.ctsnetjournals.org ...

… for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2006 Update Endorsed by the … -
SC Smith, J Allen, SN Blair, RO Bonow, LM Brass, … - Journal of the American College of Cardiology, 2006 - Am Coll Cardio Found
... article has been copublished in the May 16, 2006, issue of the Circulation (Circulation
2006;113). Copies: This document is available on the World Wide Web ...

Epidemiology and treatment of chronic bronchitis and its exacerbations -
P Ball - Chest, 1995 - Am Coll Chest Phys
... This information is current as of August 31, 2006 http://www.chestjournal.org the
World Wide Web at: The online version of this article, along with updated ...

Source: Google Scholar
 
 

Study Provides Further Support For Cardiovascular Safety Of Over-The-Counter Doses Of Naproxen Sodium

Article Date: 17 Nov 2006 - 0:00am (PST)
Over the past two years, there has been documented concern about the cardiovascular safety of some pain relievers and arthritis treatments.(1) New data presented at the 70th annual meeting of the American College of Rheumatology (ACR) examine the platelet inhibition of over-the-counter (OTC) doses of naproxen sodium and the findings add further to the significant body of evidence surrounding the product's cardiovascular safety.

Platelets are an element in the blood that aid blood clotting.(2) Aggregating, or accumulating, platelets can cause clotting in the arteries, which can lead to a heart attack or ischemic stroke. Previous research has found the prescription strength dose of naproxen (550mg bid)(3) to have positive antiplatelet effects, but this study represents the first time that data have been collected at the OTC dose of 220mg bid and tid.

Measuring the inhibition of serum thromboxane B2 (TXB2), researchers determined that OTC doses of naproxen sodium produced an antiplatelet effect similar to enteric-coated, low-dose aspirin and prescription strength naproxen. Researchers did not examine any clinical endpoint, so the clinical significance of these data is undetermined. The findings were presented this week.

Article continues below and (thank you)
 
"As healthcare professionals who treat arthritis, we're facing a dilemma in how to best treat our patients in need of pain relief -- many of whom have chosen to forego treatment because of concerns about medication safety," said study author Michael Schiff, M.D., of the Denver Arthritis Clinic. "This new research gives us increased confidence in the cardiovascular profile of naproxen sodium, such as that found in Aleve, as an OTC pain reliever."

Methodology and Findings

This study was a single-center, randomized, open-label, placebo- controlled, two-period crossover trial with an intent-to-treat (ITT) population of 48 healthy men and women. Forty one participants who met the study criteria were given one of three regimens of naproxen sodium (220 mg two times daily [n=11], 220 mg three times daily [n=9], 550 mg two times daily [n=11]) or placebo [n=10] for seven days. After a washout period of at least six days, subjects received aspirin 81 mg once daily for seven days for comparison purposes.

The primary endpoint in the study was the inhibition of TXB2, measured through blood and urine samples that were collected at baseline and 12 hours after the last dose of medication.

The mean (+/- SD) degree of serum TXB2 inhibition was

97.9% (+/- 3.20%) for naproxen 220 mg two times daily
99.4% (+/- 0.77%) for naproxen 220 mg three times daily
99.6% (+/- 0.69%) for naproxen 550 mg two times daily
 
"These data, confirming that the OTC dose of naproxen sodium has a measurable antiplatelet effect, add to the body of evidence about the safety of this compound," said study author Marc C. Hochberg, M.D., M.P.H., Professor of Medicine and Head of the Rheumatology and Clinical Immunology Division, University of Maryland School of Medicine. "This information, along with other research reported in leading medical journals, helps to distinguish the safety of products within the NSAID class and supports the safety profile of naproxen sodium as an OTC pain reliever for patients with arthritis."

About Naproxen/ALEVE

Naproxen has been used for more than 30 years in the United States as a prescription product. Since its introduction as an OTC product in June 1994, ALEVE(R) (naproxen sodium) has been used by millions of Americans as a safe and effective pain reliever for more than a decade. With the convenience of all day relief with just two pills, ALEVE can be used for the treatment of aches and pains due to minor arthritis pain, muscle aches, backache, headache, toothache, menstrual pain and pain associated with the common cold.

About Bayer Consumer Care

The Consumer Care Division of Bayer HealthCare LLC, is headquartered in Morristown, N.J. Bayer's Consumer Care Division is among the largest marketers of over-the-counter medications and nutritional supplements in the world. Some of the most trusted and recognizable brands in the world today come from the Bayer portfolio of products. These include Bayer(R) Aspirin, ALEVE(R), Alka-Seltzer Plus(R), Bactine(R), RID(R), Phillips(R)'s Milk of Magnesia, Midol(R), Alka-Seltzer(R), One-A-Day(R) vitamins and Flintstones(TM) vitamins.

Bayer HealthCare, a subsidiary of Bayer AG, is one of the world's leading, innovative companies in the health care and medical products industry based in Leverkusen/Germany. In 2005, the Bayer HealthCare subgroup generated sales amounting to some 9.4 billion Euro. Bayer HealthCare employed 33,800 people worldwide in 2005. The company combines the global activities of the divisions Animal Health, Consumer Care, Diabetes Care, Diagnostics and Pharmaceuticals. Since January 1, 2006 the new Pharmaceutical Division consists of the former Biological Products and Pharmaceutical Division and now comprises three business units: Hematology/Cardiology, Oncology and Primary Care. Bayer HealthCare's aim is to discover and manufacture products that will improve human and animal health worldwide. The products enhance well- being and quality of life by diagnosing, preventing and treating diseases.

(1) Salpeter M, Gregor P, Meta-analysis: Cardiovascular events associated with non-steroidal anti-inflammatory drugs. American Journal of Medicine. 2006; 119: 552-559.

(2) American Heart Association Cardiac Glossary, http://americanheart.org/presenter.jhtml?identifier=3038599#pacemaker

(3) Capone M, Tacconelli S, Clinical pharmacology of platelet, monocyte and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. Circulation. 2004; 109:1468-1471.

Bayer HealthCare Consumer Care Division
Bayer HealthCare Consumer Care Division
 
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