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Recent News and Articles on the Keywords: 0.15 + web  Related to the article below (Last Update: 8/4/2008)

Salix Pharmaceuticals Reports 2Q2008 Results
FOXBusiness -
Interested parties can access the conference call by way of web cast or telephone. The live web cast will be available at www.salix.com. A replay of the web ...SLXP
Boots & Coots Reports Second Quarter and Six Month Results
MarketWatch -
... to these forward-looking statements are found in Boots & Coots' SEC filings, which are available free of charge on the SEC's web site at www.sec.gov. ...WEL
Anadarko Announces Second-Quarter Results
WELT ONLINE, Germany -
A replay of the call will also be available on the Web site for approximately 30 days following the conference call. ANADARKO OPERATIONS REPORT For more ...APC - BOM:500312 - WAR:CFL
Telecom Italia unveils iPhone pricing plans
Telecom Paper (subscription), Netherlands - Jul 14, 2008
The iPhone customers who sign up to iPhone Web Oversize package can make calls to all landlines and mobiles in Italy for EUR 0.15 per minute and text ...

FLEXNEWS
AGL Resources Reports Second Quarter 2008 Results; Reaffirms ...
Earthtimes (press release), UK - Jul 31, 2008
Reported GAAP diluted earnings per share (EPS) of $(0.15), compared to EPS of $0.40 per diluted share for second quarter 2007 -- Earnings, excluding the ...
The Phoenix Companies, Inc. Second Quarter 2008 Earnings MarketWatch
Acura Pharmaceuticals, Inc. Reports Second Quarter 2008 Financial ... CNNMoney.com (press release)
Kaydon Corporation Reports Second Quarter Results Barron's Blogs
Trading Markets (press release) - Earthtimes (press release)
all 1,243 news articles »  ATG - ACUR - KDN

Earthtimes (press release)
TheStreet.com Reports Second-Quarter Financial Results
MarketWatch - Jul 31, 2008
It engages audiences on video and digital platforms through some of the Web's best known sites: TheStreet.com, RealMoney.com, Stockpickr.com, ...
Omnicare Reports Second Quarter Results Genetic Engineering News (press release)
Shutterfly Announces Second Quarter 2008 Financial Results TMC Net
Xantrex(TM) Technology Inc. Reports 2008 Second Quarter MarketWatch
all 859 news articles »  TSCM - OCR - SFLY

WELT ONLINE
Travelzoo Reports Second Quarter 2008 Results
MarketWatch - Jul 24, 2008
In May 2008, Travelzoo began publishing its Web site and its weekly Top 20(R) list in Spain, after having operated a sales office in Barcelona since ...
Lattice Semiconductor Reports Second Quarter Financial Results CNNMoney.com
Glimcher Reports Second Quarter 2008 Results Earthtimes (press release)
PCTEL Posts $20.3 Million in Second Quarter Revenue from ... Centre Daily Times
MarketWatch
all 773 news articles »  LSCC - CTXS - TZOO
Keynote Reports Fiscal Third Quarter 2008 Results
MarketWatch - Jul 29, 2008
Keynote currently provides its services to 52 percent of the comScore Media Metrix's top 50 Web sites and approximately 45 percent of the Fortune 100 ...KEYN
Kaboose Reports Record Second Quarter 2008 Results with Revenue ...
Canada NewsWire (press release), Canada - Jul 31, 2008
The webcast will be archived on the same web page for 30 days following the live call. The second quarter financial statements and related management's ...TSE:KAB - BOM:532354 - GIS
Ubuntu Security Notice - mozilla-thunderbird, thunderbird ...
Help Net Security, Croatia - Jul 25, 2008
If a user had Javascript enabled and were tricked into opening a malicious web page, an attacker could cause a denial of service via application crash, ...
Source: Google News

Automatic text location in images and video frames -
AK Jain, B Yu - Pattern Recognition, 1998 - doi.ieeecomputersociety.org
... CPU carrier images size ( ) time (s) Advertisement 26 548 769 99.2 0.15 Web
image 54 385 234 97.6 0.11 Color image 30 769 537 72.0 0.40 ...

Late events of translation initiation in bacteria: a kinetic analysis -
W Focuses, NPG Contact - The EMBO Journal, 2000 - nature.com
... GTP hydrolysis was observed due to the uncoupled GTP hydrolysis by IF2 on the ribosomes;
the rate constant of the multiple turnover reaction was 0.15 0.02/s ...

JouleTrack-A Web Based Tool for Software Energy Profiling -
A Sinha, AP Chandrakasan - Proceedings of the 38th Design Automation Conference (DAC … - doi.ieeecomputersociety.org
Page 1. JouleTrack - A Web Based Tool for Software Energy Profiling Amit Sinha Anantha
P. Chandrakasan ... 0 0.05 0.1 0.15 0.2 0.25 Average Current (A) ...

The anatomy of a large-scale hypertextual Web search engine -
S Brin, L Page - Computer Networks and ISDN Systems, 1998 - Elsevier
... Same query repented (IO mostly cached t CPU time (5) 0.09 I .77 0.15 1.31 ... A Web
search engine is a very rich environment for research ideas. ...

[PS] Overview of the TREC-8 Web Track -
D Hawking, E Voorhees, N Craswell, P Bailey - Proc. of TREC-8 - research.microsoft.com
... isw50t .029 0 0.05 0.1 0.15 0.2 0.25 0.3 0.35 0.4 0.45 0.5 0 0.05 0.1 0.15
0.2 0.25 0.3 0.35 0.4 0.45 0.5 Small Web Ad Hoc Figure 3 ...
-

Measuring the Independence of Central Banks and Its Effect on Policy Outcomes -
A Cukierman, SB Web, B Neyapti - The World Bank Economic Review, 1992 - World Bank
... 0.00 2 Policy formulation 0.15 a. Who formulates monetary policy? Bank alone
1.00 ... 1.00 Central bank has no influence 0.00 3 Objectives 0.15 ...

Graph structure in the Web -
A Broder, R Kumar, F Maghoul, P Raghavan, S … - Computer Networks, 2000 - Elsevier
... an URL into an internal id or vice versa, and then only 0.15 ?s/link ... manner, but
is subject to various rules designed to avoid overloading Web servers, avoid ...

Finding information on the World Wide Web: the retrieval effectiveness of search engines -
M Gordon, P Pathak - Information Processing and Management, 1999 - Elsevier
Page 1. Finding information on the World Wide Web: ... Abstract Search engines
are essential for ?nding information on the World Wide Web. ...

Cost estimation for web applications -
M Ruhe, R Jeffery, I Wieczorek - Software Engineering, 2003. Proceedings. 25th International …, 2003 - ieeexplore.ieee.org
... revealed thirty-five potential cost factors in the area of web development, some ...
Novelty of Requirements 0.10 0.15 0.11 Importance of SW Maintenance 0.19 0.24 ...

Stable isotope food web studies: a case for standardized sample treatment -
U Jacob, K Mintenbeck, T Brey, R Knust, K Beyer - Marine Ecology Progress Series, 2005 - esep.de
... Stable isotope food web studies: a case for ... Experimental precision (based on standard
deviation of replicates of a peptone standard) was =0.15? for carbon ...

Source: Google Scholar
 
 

Phase II Trial Of Continuous Low-Dose Oral Cyclophosphamide And Celecoxib For Metastatic Renal Cell Carcinoma

Article Date: 22 Nov 2006 - 0:00am (PST)
UroToday.com - Traditional chemotherapeutic regimens given at high doses in an intermittent fashion have demonstrated little to no activity in the treatment of metastatic renal cell carcinoma (RCC). However, there is some evidence to suggest that when selected chemotherapies are given at lower, continuous doses (so-called metronomic dosing), there can be significant anti-angiogenic and immunomodulatory effects resulting in anti-tumoral activity that would not be realized with standard dosing.

It is well accepted that RCC is a highly antiangiogenic tumor and therefore might be receptive to such a treatment strategy. Furthermore, it has been demonstrated that RCC overexpresses cyclooxygenase 2 (COX-2) and that inhibitors of COX-2, such as celecoxib, have demonstrated significant anti-tumoral activity in preclinical models. These same preclinical models have demonstrated synergy between cyclophosphamide, given at metronomic or low continuous dosing, in combination with celecoxib. Here, Krzyzanowska and colleagues examine the activity of low dose oral cyclophosphamide in combination with celecoxib in the treatment of metastatic RCC.

Article continues below and (thank you)

 
In this phase II clinical trial conducted at two institutions in Canada, 36 patients were treated orally with Celecoxib 400 mg BID and 50 mg cyclophosphamide per day. Of these, 32 were evaluable for response. Median age was 62 years, 8 patients had received prior therapy, and 11 patients had a prior nephrectomy. One patient had a partial response and 3 patients had stable disease for > 6 months. The median progression free survival was 3.5 months and the median overall survival was 14.5 months. Overall, the treatment was well tolerated with minimal toxicity.

While based on sound biology and evidence of efficacy in the preclinical setting, the combination of low dose cyclophosphamide and celecoxib has little activity in metastatic renal cell carcinoma.

Cancer Chemother Pharmacol, Online First

Reviewed by UroToday.com Contributing Editor Christopher G. Wood, MD

UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice.

To access the latest urology news releases from UroToday, go to:
www.urotoday.com
 

The Molecular Basis Of Urgency: Regional Difference Of Vanilloid Receptor Expression In The Human Urinary Bladder

UroToday.com - Transient receptor potential vanilloid-1 receptor (TRPV1) is activated by capsaicin, the drug injected subcutaneously by scientists in an attempt to study C fiber sensitization. The receptor, which is tied in with calcium metabolism pathways, turns out to have an active role in two very important areas. It appears to play a central role in initiating inflammatory responses AND integrating painful stimuli.

Afferent impulses involved in signaling from normal bladder are transmitted by myelinated A? fibers which respond to distention and bladder filling, whereas noxious stimuli are transmitted by unmyelinated C-fibers. TRPV1 is expressed predominantly by primary sensory neurons involved in nociception and neurogenic inflammation. These neurons can be activated and desensitized by vanilloids, a group of chemicals which include the neurotoxin capsaicin and related compounds such as resiniferatoxin. Liu and colleagues from Sydney, Australia studied possible changes in TRPV1 mRNA expression in different regions of the bladder from female patients with sensory urgency (SU) and compared the findings with those of female patients with idiopathic detrusor overactivity (DO) and asymptomatic women. The hypothesis was that there would be an upregulation in patients with hypersensitivity disorders.

The results showed that TRPV1 mRNA from SU trigonal mucosa was significantly higher than control trigonal mucosa or SU bladder body mucosa. In contrast, in DO patients, there was no difference between trigonal mucosa and body mucosa. TRPV1 mRNA expressed in SU trigonal mucosa was significantly inversely correlated with the bladder volume at first sensation of filling during cystometry. No such relationship was seen for DO trigonal mucosa. Bladder body mucosa failed to show changes in women with disease versus controls.

The authors conclude that their data is in line with a role for TRPV1 as a sensory integrator of chemical, physical, or inflammatory stimuli in the storage phase of bladder filling. Thus, there is a scientific basis to pursue the therapeutic use of vanilloids in disorders manifested by bladder hypersensitivity and urgency, despite failure of resiniferatoxin in initial phase 2 trials for interstitial cystitis.

Lu Liu, Kylie J. Mansfield, Ika Kristiana, Kenneth J. Vaux, Richard J. Millard, Elizabeth Burcher
Neurourology and Urodynamics: Early View

Reviewed by UroToday.com Contributing Editor Philip Hanno MD, MPH

UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice.

To access the latest urology news releases from UroToday, go to:
www.urotoday.com

Copyright © 2006 - UroToday
 
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