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Recent News and Articles on the Keywords: 2006 + 0.21 + web  Related to the article below (Last Update: 8/4/2008)

InvestSource, Inc.: NeoReader for Apple's iPhone Now Available for ...
Trading Markets (press release), CA -
The S&P finished the week up 0.02 percent, and the Nasdaq finished up 0.21 percent. Bond prices edged higher in Friday's trading. The yield on the benchmark ...UNM - CME - MHGC

CPI Financial
ADP Reports Fiscal 2008 Results; Provides Fiscal 2009 Guidance
Trading Markets (press release), CA - Jul 31, 2008
ADP's news releases, current financial information, SEC filings and Investor Relations presentations are accessible at the same Web site. ...
Banner Corporation Announces Second Quarter Results; Includes ... MarketWatch
Bank of Hawaii Corporation Second Quarter 2008 Financial Results Trading Markets (press release)
all 1,045 news articles »  ADP - BOH - BANR
Highwoods Properties Reports Second Quarter 2008 Results
Trading Markets (press release), CA - Jul 29, 2008
A live listen-only Web cast can be accessed through the Company's web site at www.highwoods.com under the "Investor Relations" section. ...HIW
VIGNETTE CORPORATION: Vignette Reports Second Quarter 2008 ...
Trading Markets (press release), CA - Jul 25, 2008
Third quarter 2008 GAAP net income is currently expected to be between $(0.21) and $(0.07) per share on a fully diluted basis. The company expects third ...VIGN - OTC:CMTX
Omniture Reports Second Quarter 2008 Financial Results
MarketWatch - Jul 23, 2008
The webcast will be available on the "Investor Relations" section of the company's corporate web site at www.omtr.com. A replay of the conference call will ...OMTR
Dominion Announces Second-Quarter 2008 Earnings
Earthtimes (press release), UK - Jul 31, 2008
4) Refer to schedules 2 and 3 for details related to items excluded from operating earnings, or find "GAAP Reconciliation" on Dominion's Web site at ...D
CPN In-Fill & Delineation Drilling on the Rovina Porphyry, Romania ...
FOXBusiness - Jul 23, 2008
For example RRD-59 intersected 8 m at 0.46 g/t Au an 0.21% Cu, while drill hole RRD-61 intersected 52 m at 0.17 g/t Au and 0.13% Cu. ...TSE:CPN - OTC:CMTX
UMC Reports 2008 Second Quarter Results
FOXBusiness - Jul 30, 2008
UMC can be found on the web at http://www.umc.com . Except for statements in respect of historical matters, the statements in this release contain ...UMC

RTT News
Omnicare Reports Second Quarter Results
Genetic Engineering News (press release), NY - Jul 31, 2008
The conference call will be webcast live at Omnicare's Web site at www.omnicare.com by clicking on "Investors" and then on "Conference Calls," and will be ...
Mothers Work Reports Third Quarter Fiscal 2008 Earnings Earthtimes (press release)
all 858 news articles »  OCR - MWRK

WELT ONLINE
Carolina Bank Holdings, Inc. Announces Improved Asset Quality and ...
MarketWatch - Jul 16, 2008
Further information is available on the Company's web site: www.carolinabank.com. This press release contains forward-looking statements regarding future ...
Huntington Bancshares Reports 2008 Second Quarter Net Income of ... Earthtimes (press release)
all 467 news articles »  CLBH - HBAN - FCMC
Source: Google News

[PDF] … of a web-based teaching module and gender on accounting students? ethical judgements Copyright 2006 …
W James, L McManus, N Subramaniam - eprints.qut.edu.au
Page 1. 1 A study on the effect of a web-based teaching module and gender on accounting
students? ethical judgements Copyright 2006 (The authors) ...
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Business Summary: Communications (MIC: 10.1 SIC: 7375 NAIC: 518210)
QMJS Dec, I Dividends, ADER Pay, DA Status - doi.wiley.com
... 0.05 0.29 0.52 0.67 2005 0.11 0.46 0.47 0.38 2006 0.21 ... .. ... expects full-year 2006
revenue growth to be in line ... M5K 1A1 Telephone: 416-360-8700 Web Site: www ...

Generating maps of web pages using cellular automata
H Azzag, D Ratsimba, D Da Costa, G Venturini, C … - … of the 15th international conference on World Wide Web, 2006 - portal.acm.org
... Keywords: Web pages, visualization, unsupervised clustering, cel- lular ... WWW 2006,
May 23?26, 2006, Edinburgh, Scotland ... 0.35 [0.06] 4.2 [0.6] 0.59 [0.21] 0.17 6 ...
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[CITATION] Web Mining System for Mobile-Phone Marketing
VII Chapter - Business Applications and Computational Intelligence, 2006 - Idea Group Pub.
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Effort estimation modeling techniques: a case study for web applications
G Costagliola, S Di Martino, F Ferrucci, C Gravino … - Proceedings of the 6th international conference on Web …, 2006 - portal.acm.org
... could be considered effective indicators in predicting development efforts of web
applications, and ... by the author/owner(s). ICWE'06, July 11-14, 2006, Palo Alto ...

Extracting news-related queries from web query log -
M Maslov, A Golovko, I Segalovich, P Braslavski - … of the 15th international conference on World Wide Web, 2006 - portal.acm.org
... extracted event-related queries (Jan-31-2006) Original query ... Recall 0.21 0.27 0.22
0.37 F1 0.34 0.41 0.35 ... of a Very Large Topically Categorized Web Query Log. ...
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[PDF] The problem of ontology alignment on the web: a first report -
D Fossati, G Ghidoni, B Di Eugenio, I Cruz, H Xiao … - 2nd Web as Corpus Workshop (associated with the 11th …, 2006 - acl.ldc.upenn.edu
... Each document came from a distinct web page, so there was no overlap in the
data to be compared. ... Egypt 0.17 0.24 0.32 0.21 0.31 0.30 0.27 ...

STUDENT TEACHERS?ACCEPTANCE OF A WEB-BASED INFORMATION SYSTEM -
EYM CHEUNG, J SACHS - ??????- ?? ?? ?? ? ?, 2006 - J-STAGE
132 Psychologia, 2006, 49, 132?141 ... WEB-BASED INFORMATION SYSTEM 135 ... experience on
ease of use in H3, though not statistically significant (? = 0.21, p = .106 ...

[CITATION] Results 21-26 of about 26 for related: scholar. lib. vt. edu/theses...(0.21 seconds)
SV Tech-Home

Web Information Retrieval in Collaborative Tagging Systems -
SO Choy, AK Lui - … of the 2006 IEEE/WIC/ACM International Conference on Web …, 2006 - portal.acm.org
... Conference Proceedings)(WI'06) 0-7695-2747-7/06 $20.00 ? 2006 ... where U is the URL
of a web resource, T ... maps 0.32 link links 0.16 image images 0.21 video videos ...

Source: Google Scholar
 
 

New Study Finds On/off Switch For Septic Shock

Article Date: 18 Nov 2006 - 22:00pm (PST)
According to a new study, septic shock--a dangerous, often deadly runaway immune response--is controlled by a genetic on/off switch. The research also suggests how a drug might temper sepsis. This is the first time this genetic mechanism has been revealed in an experimental animal.

The study by Robert Schneider, Ph.D., the Albert B. Sabin Professor of Microbiology and Molecular Pathogenesis at NYU School of Medicine and his colleagues, was published in the November 3, 2006 advance online edition of the journal Genes & Development.

A killer and a protector

Septic shock is the nation's 10th most frequent cause of death and the leading cause of hospital-related mortality. Bacterial infection, notably the toxins that are part of the bacterial cell wall, stimulate the inflammatory response which can spin out of control. Sepsis progresses swiftly from chills, fever and shallow breathing, to dilated and leaky blood vessels, a lack of blood supply in the body's organs, multiple organ failure and, often, death.

Article continues below and (thank you)
 
Infection causes the body's immune system to produce protective proteins called cytokines. Problems arise when the body is unable to turn off cytokine production and they overwhelm the body, says Dr. Schneider. "The resulting cytokine storm is, for example, what kills people when they are infected with anthrax and, we think, an important factor in what killed people in the flu pandemic of 1918," he says.

Dr. Schneider and his colleagues focused on one of the key genes that regulate cytokine production called auf1, which has been extensively studied in tissue culture but not in animals. In an attempt to move the research closer to the clinical setting, the team genetically engineered and bred mice lacking the auf1 gene, a so-called knock-out mouse. Then, mice with the gene and mice without it were exposed to a bacterial toxin that causes mild food poisoning. The normal mice had little problem fending off the endotoxin. "The mice without the gene died due to an uncontrolled septic-shock like response--their blood vessels burst, their spleens were destroyed," says Dr. Schneider. Mortality was five-fold higher in mice without the auf1 gene.

Further research showed where auf1 functions at the molecular level, he says. In normal mice, the scientists found that auf1 steps into action once the immune response is activated and after cytokine production gets underway. The action is pronounced: messenger RNAs (mRNAs) which are blueprints for very specific cytokines--namely interleukin-1 beta, tumor necrosis factor alpha and COX-2--are degraded. That process of degrading the mRNAs shuts off production of these cytokines.
 
In the study, mice lacking the auf1 gene do not seem to have that off switch; their cytokine levels were greatly elevated. A cytokine storm had caused sepsis in these animals.

In summary, auf1 is a protector that can stop an infection from progressing to septic shock, explains Dr. Schneider. It does so by helping with cytokine production and then tempering the production of these proteins. Auf1 acts like a cytokine on/off switch.

The future possibilities

Dr. Schneider believes auf1 makes an excellent target for the development of therapeutics. For example, a drug could turn on auf1 or stabilize its activity as a way to specifically tone down production of those cytokines that are the major players in sepsis, he says. His study results might also help explain why many previous sepsis drug trials have failed. The cytokine storm needs to be turned off at its source, he says, and auf1 offers the on/off switch to do just that.

###

The paper was authored by Dr. Schneider along with Navid Sadri, an M.D./Ph.D. student in his lab and former student Jin-Yu Lin, Ph.D.., who is currently a post-doctoral fellow at Yale University School of Medicine.

Contact: Jennifer Choi
New York University Medical Center and School of Medicine
 
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