Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California

 

Recent News and Articles on the Keywords: 0.31 + 2006 + web  Related to the article below (Last Update: 8/4/2008)

Best of the Best from the preps pages from Troy/Rochester
Detroit Free Press, United States - Aug 3, 2008
She also finished as the catcher who handled the school's best pitching staff ever (Jordan Wheatley was 25-3 with a 0.31 ERA, Kristen Fleming went 11-1 with ...LON:BEST

RTT News
Omnicare Reports Second Quarter Results
Genetic Engineering News (press release), NY - Jul 31, 2008
The conference call will be webcast live at Omnicare's Web site at www.omnicare.com by clicking on "Investors" and then on "Conference Calls," and will be ...
Fiserv Reports Second Quarter 2008 Results Trading Markets (press release)
all 858 news articles »  OCR - FISV - TSCC
Percutaneous Spine Biopsy: A Meta-Analysis
Journal of Bone and Joint Surgery (subscription) - Aug 1, 2008
With the numbers available, the adequacy rates (slope = 0.31, p = 0.09) and accuracy rates (slope = 0.24, p = 0.11) of the specimens increased slightly as ...
American Medical Systems Reports Second Quarter Revenue of $129.8 ...
MarketWatch - Jul 29, 2008
A live web cast of the call will be available through the Company's corporate website at www.AmericanMedicalSystems.com and available for replay three hours ...AMMD
Prophecy drills 45.5 metres of 0.33% copper and 0.003% Molybdenum ...
Canada NewsWire (press release), Canada - Jul 28, 2008
At Okeover, the objectives of the recent program were achieved and expanded the mineralized area of the North Lake Zone (calculated in 2006 by NC Carter, ...CVE:PCY - TSE:X - CVE:ETF
InvestSource, Inc.: CEO of WGL Entertainment Holdings, Inc ...
Trading Markets (press release), CA - Jul 31, 2008
Separately, President Bush signed the housing bill into law, giving support to Fannie Mae (FNM 12.21, +0.61) and Freddie Mac (FNM 8.73, +0.31), ...BYI - DIS - OTC:GNPI
Bank of Hawaii Corporation Second Quarter 2008 Financial Results
Trading Markets (press release), CA - Jul 28, 2008
Net charge-offs for the six months ended June 30, 2008 were $10.1 million, or 0.31 percent annualized of total average loans and leases compared to $6.0 ...BOH
Six Holes Completed at Okeover copper/molybdenum project in BC
Canada NewsWire (press release), Canada - Jul 8, 2008
For further information: about Prophecy, please visit our web site at www.prophecyresource.com or contact us toll-free at (888) 818-8748.CVE:PCY - TSE:X - CVE:ETF
Phoenix Technologies Ltd. Reports Third Quarter FY2008 Financial ...
Earthtimes (press release), UK - Jul 22, 2008
Investors are invited to listen to a live audio web cast of the quarterly conference call on the investor relations section of the Company's website at ...PTEC
InvestSource, Inc.: PureSpectrum, Inc. Announces New Chairman of ...
Trading Markets (press release), CA - Jul 31, 2008
President Bush signed the housing bill into law, giving support to Fannie Mae (FNM 12.21, +0.61) and Freddie Mac (FNM 8.73, +0.31), while the SEC is ...PINK:OOCP - CPN - ACPW
Source: Google News

Relationship between web links and trade -
R Baeza-Yates, C Castillo - … of the 15th international conference on World Wide Web, 2006 - portal.acm.org
... WWW 2006, May 23?26, 2006, Edinburgh, Scotland. ... Table 2: Comparison of cross-
similarities between Web links and exports. ... Brazil 0.26 0.34 0.31 0.32 0.32 ...

A new look at evidence of scholarly citation in citation indexes and from web sources -
L Vaughan, D Shaw - Scientometrics, 2008 - Springer
... Print/subscription journal article 857 0.31 0.43 0.75 ... one citing work appears on
several web pages. ... dominant data source of research evaluation [M EHO , 2006]. ...

[PDF] The Results of Falcon-AO in the OAEI 2006 Campaign -
W Hu, G Cheng, D Zheng, X Zhong, Y Qu - Ontology Matching - dit.unitn.it
... World Wide Web Conference (WWW?06).(2006) 23?31 5 ... of the 4th International Semantic
Web Conference (ISWC?05).(2005 ... 259 0.72 0.72 42.3 s 260 0.90 0.31 0.8 s ...

[CITATION] Mehta, Nikil (2006-05-31) Time-multiplexed FPGA overlay networks...
W Results

[PDF] … of a web-based teaching module and gender on accounting students? ethical judgements Copyright 2006 …
W James, L McManus, N Subramaniam - eprints.qut.edu.au
Page 1. 1 A study on the effect of a web-based teaching module and gender on accounting
students? ethical judgements Copyright 2006 (The authors) ...
-

Web Search Engine as a Bee Hive -
P Navrat, M Kovacik - … of the 2006 IEEE/WIC/ACM International Conference on Web …, 2006 - doi.ieeecomputersociety.org
... 0.32], source24[0.32], source64[0.32], source92[0.31], source78[0.26 ... Proceedings
of the 2006 IEEE/WIC/ACM International Conference on Web Intelligence (WI ...

Wikipedias: Collaborative web-based encyclopedias as complex networks -
V Zlatic, M Bo?icevic, H ?tefancic, M Domazet - Physical Review E, 2006 - APS
... 016115-4 WIKIPEDIAS: COLLABORATIVE WEB-BASED? PHYSICAL REVIEW E 74, 016115 2006
TABLE II ... 10.83 9.22 All WCC 1.10 0.28 0.49 0.37 1.04 0.55 0.31 0.81 0.28 ...

Personalisation of Web Search: An Agent Based Approach
GL Ligon, MB Balachandran, D Sharma - LECTURE NOTES IN COMPUTER SCIENCE, 2006 - Springer
... Springer-Verlag Berlin Heidelberg 2006 ... A series of tests was carried out to investigate
the effectiveness of the web search provided by ... Job 1.00 0.55 1.00 0.31 ...

[PDF] The role of ciliates within the microbial food web in the eutrophicated part of Ka?tela Bay (Middle … -
N Bojanic, M ?olic, N Krstulovic, S ?estanovic, … - Scientia Marina, 2006 - Consejo Superior de Investigaciones Cientificas
... for both parameters were found in August 1999, when 1.01 ? 0.31 ? 10 6 ... MAR., 70(3),
September, 2006, 431-442. ... RELATIONSHIPS WITHIN MICROBIAL FOOD WEB ? 435 ...
-

Linearity in the aggregate effects of multiple predators in a food web -
OJ Schmitz, L Sokol-Hessner - Ecology Letters, 2002 - Blackwell Synergy
... at a constant density of three spiders to approximate natural densities of 2.5 ?
0.31 (1 SE) m ... (2006) Multiple predator effects in an intertidal food web. ...

Source: Google Scholar
 
 

Two-Drug Therapy Could Become New Standard Of Care For Moderate-to-Severe Male Overactive Bladder

Article Date: 19 Nov 2006 - 0:00am (PST)
A major clinical trial finds that a combination of two common medications -- tolterodine (Detrol LA) and tamsulosin (Flomax) -- works better than either drug alone for men struggling with lower urinary tract symptoms, including tough-to-treat overactive bladder (OAB).

"A full 80 percent of men with moderate-to-severe OAB -- which is characterized by symptoms such as urgent and frequent urination -- who received these two drugs together reported a real benefit within three months of treatment," says the study's lead author, Dr. Steven A. Kaplan, professor of urology at Weill Cornell Medical College and attending urologist at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City. "In contrast, patients receiving either tolterodine or tamsulosin alone reported improvements that were little more than those seen by patients on placebo," he adds.

"Based on these findings, we believe that a combination of medications such as tolterodine/tamsulosin may become a new 'gold standard' for the treatment of bothersome moderate-to-severe overactive bladder symptoms in this patient population," Dr. Kaplan says.

Article continues below and (thank you)
 
The NewYork-Presbyterian/Weill Cornell expert will present the findings Tuesday, Nov. 14, at 10 a.m., at a JAMA news briefing in New York City. The study will be published in the Nov. 15 edition of the Journal of the American Medical Association, a special issue devoted to men's health.

Experts estimate that 10 million American men aged 40 and over suffer from overactive bladder. The current standard of care involves the use of an "antimuscarinic" drug such as tolterodine to help alleviate OAB symptoms. Antimuscarinics help regulate bladder contractions through their effects on the bladder's detrusor muscle.

In many cases, doctors may also suspect that an enlarged prostate ("benign prostatic hyperplasia" or BPH) is an underlying cause of OAB. In those instances, they will prescribe an "alpha-adrenergic receptor antagonist" drug such as tamsulosin, which eases symptoms through its effect on prostate muscle tone.

"The problem is that men with OAB and enlarged prostate can have an overactive bladder without it being caused by this prostatic condition, so they don't respond to drugs such as tamsulosin" Dr. Kaplan notes. "Likewise, some patients do not respond to tolterodine alone, either."
 
However, urologists have reported anecdotal success in using both of these agents together for moderate-to-severe male OAB. In this study, Dr. Kaplan and colleagues at NewYork-Presbyterian/Weill Cornell -- along with researchers at the University of Texas Southwestern Medical Center and the Medical University of South Carolina -- tested this approach in a double-blinded, randomized clinical trial involving more than 850 patients treated at 95 urology clinics across the U.S. The study was funded by Pfizer Inc., the maker of Detrol LA.

Patients were all 40 years of age or older (average age 62) with symptoms suggestive of an enlarged prostate and a history of moderate-to-severe overactive bladder, including a frequent urination and urgency with or without incontinence. Patients with any history of prostate surgery or prostate cancer were excluded from the study.

The 12-week, double-blinded, placebo-controlled study randomized participants into one of four treatment groups: one arm (217 patients) received a once-daily 4 milligram dose of tolterodine, a second arm (215 pts.) received 0.4 milligrams of tamsulosin once per day, a third group (225 pts.) was given both drugs in combination, while a fourth group (222 pts.) received a daily placebo.

The researchers had participants record changes in daily symptoms -- items such as frequency of urinary incontinence -- in special "bladder diaries." They also questioned each participant on their "perception of treatment benefit" at weeks 1, 6 and 12. Urinary flow rates and volume were also assessed at baseline and at week 12 via flowmeter and ultrasound.

The result: "We found a marked improvement in OAB for patients taking both drugs together, with 80 percent reporting a real treatment benefit compared to 62 percent for those on placebo," Dr. Kaplan reports. "In contrast, treatment benefit rates for monotherapy did not rise much above placebo -- 71 percent for patients taking tamsulosin and 65 percent for those given tolterodine monotherapy."

Compared to monotherapy, tolterodine/tamsulosin in combination achieved significantly higher rates of symptom reduction in terms of urgency urinary incontinence, urgency episodes without incontinence, voiding per 24 hours, and night voiding. Patients on the two-drug therapy also reported significant improvement in their quality of life compared to monotherapy or placebo, the researchers added.

Each of the three drug regimens was well-tolerated, with dry mouth being the most frequently reported symptom. Patients on combination therapy did report a higher incidence of dry mouth than those taking monotherapy (21 percent vs. 7 percent, respectively). "The reasons for this increase in dry mouth remain unclear and require further study," Dr. Kaplan says. "We have some evidence, however, that taking the drugs just before bed, rather than after dinner as in this study, could reduce risks for these and other adverse effects."

The bottom line, according to Dr. Kaplan, is that the findings "strongly support the use of these two medications in combination as safe and effective therapy for men with moderate-to-severe lower urinary tract symptoms, including OAB."

"For many men who are bothered by OAB, monotherapy -- which targets one potential cause of the illness -- is simply not enough to ease symptoms," he says. "In that context, the use of tolterodine and tamsulosin together may work much better, since it tackles the problem on multiple fronts."

Co-researchers include senior researcher Dr. Zhonghong Guan of Pfizer Inc., New York City; Dr. Tamara Bavendam and Martin Carlsson, also of Pfizer; Dr. Claus G. Roehrborn of the University of Texas Southwestern Medical Center, Dallas; and Dr. Eric S. Rovner of the Medical University of South Carolina, in Charleston.

For more information, patients may call (866) NYP-NEWS.

NewYork-Presbyterian Hospital/Weill Cornell Medical Center

NewYork-Presbyterian Hospital/Weill Cornell Medical Center, located in New York City, is one of the leading academic medical centers in the world, comprising the teaching hospital NewYork-Presbyterian and its academic partner, Weill Cornell Medical College. NewYork-Presbyterian/Weill Cornell provides state-of-the-art inpatient, ambulatory and preventive care in all areas of medicine, and is committed to excellence in patient care, research, education and community service. NewYork-Presbyterian ranks sixth on the U.S.News & World Report's list of top hospitals.

NewYork-Presbyterian Hospital
425 East 61st St., Fl. 7
New York, NY 10021
United States
http://www.nyp.org
 
Google
Web www.iconocast.com
 
 
 

 

Continue News With: News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services. Home

 
 © 2002-2006

Keywords::

Contact Iconocast

Home Page