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Recent News and Articles on the Keywords: flu vaccine + flu + vaccination  Related to the article below (Last Update: 8/4/2008)


BBC News
Q&A: Flu vaccine for children
Telegraph.co.uk, United Kingdom -
Flu could be virtually wiped out if all under 16s were vaccinated against the disease, a new report suggests. Kate Devlin answers some common queries. ...
Flu jabs for under-fives could reduce all infections by two-thirds Independent
Child flu jabs 'protect everyone' BBC News
Flu jabs for under-fives could benefit the whole population, a ... Belfast Telegraph
ITV.com - Manchester Evening News
all 182 news articles »
Flu Vaccine May Not Protect Seniors Well
Science Daily (press release) -
2 issue of The Lancet adds fuel to the growing controversy over how well the flu vaccine protects the elderly. The study of more than 3500 Group Health ...
MedImmune ships Flu-Mists for winter
Bizjournals.com, NC -
... the 2008-2009 flu season, more than in years past, to more locations than ever before, including 200 school-based vaccination programs and university ...
FluMist(R) Now Available for the 2008-2009 Flu Season CNNMoney.com (press release)
FluMist now available for flu prevention Prescribing Reference
FluMist(R) Now Available for the 2008-2009 Flu Season PR Newswire (press release)
all 11 news articles »  AZN

NHS Choices
Flu jab and pneumonia
NHS Choices, UK -
This study found that flu vaccination appears to offer little protection from community acquired pneumonia (CAP), a common complication of flu, ...
Bacteria were the real killers in 1918 flu pandemic New Scientist (subscription)
all 3 news articles »
In Elderly, Flu Vaccine Might Not Protect From Pneumonia Infections
Medical News Today, UK - Aug 2, 2008
As a result, the flu vaccine is administered yearly for a predicted set of strains meant to protect against that year's mixture. A common complication of ...
Flu shots may not protect the elderly
Chicago Tribune, United States - Aug 1, 2008
The flu vaccine might not protect seniors as much as previously thought, according to a study of more than 3500 patients over age 65 that found no link ...
Study raises questions about flu vaccine's effectiveness
Globe and Mail, Canada - Aug 1, 2008
They determined that vaccination failed to significantly reduce the incidence of pneumonia, suggesting the benefit of flu shots among some groups of seniors ...

eMaxHealth.com
Seniors Don't Benefit From Flu Vaccine
eMaxHealth.com, NC - Aug 1, 2008
Researchers say that older people suffering chronic conditions, such as lung disease, heart disease, diabetes, have even higher flu risk despite vaccination ...

ChattahBox
Flu Vaccine Not Effective In Protecting Elderly From Pneumonia
ChattahBox, MA - Aug 1, 2008
Washington (ChattahBox) - Researchers have come out and state dthat they have found that the flu vaccine does not actually protect elderly people from ...

BBC News
Flu jabs 'can't stop pneumonia'
BBC News, UK - Aug 1, 2008
A spokesman for the Health Protection Agency, which monitors the uptake of flu vaccine in England and Wales, said "at-risk" groups should carry on getting ...
Source: Google News

The Efficacy of Influenza Vaccine in Elderly Persons: A Meta-Analysis and Review of the Literature -
PA Gross, AW Hermogenes, HS Sacks, J Lau, RA … - Annals of Internal Medicine, 1995 - annals.highwire.org
... JAMA. 1990; 264:1139-41. 52. Schmitz R. Influenza vaccination in the first year
of the Medicare influenza vaccine benefit. Cambridge, MA: Abt Associates; 1994. ...

Effectiveness of Influenza Vaccine in Health Care Professionals A Randomized Trial -
JA Wilde, JA McMillan, J Serwint, J Butta, MA O' … - JAMA, 1999 - Am Med Assoc
... basis; influenza vaccine recipients who did not demonstrate a 4-fold increase in
antibody titers after vaccination remained in the influenza vaccine group for ...

Prevention and control of influenza: recommendations of the Advisory Committee on Immunization … -
NM Smith, JS Bresee, DK Shay, TM Uyeki, NJ Cox, RA … - MMWR Recomm Rep, 2006 - archives.hellis.org
... Principal changes include 1) recommending vaccination of children aged 24-59 months ...
the importance of administering 2 doses of influenza vaccine for children ...

A cognitive model of the antecedents and consequences of satisfaction decisions
RL Oliver - Journal of Marketing Research, 1980 - JSTOR
... study on a nonrecurring federal flu vaccination program. ... attitudes and intentions
toward the flu inoculation were ... size SMSA before the vaccine became available ...

Patient acceptance of influenza vaccination. -
NH Fiebach, CM Viscoli - Am J Med, 1991 - ncbi.nlm.nih.gov
... university hospital-based general medicine clinic during the fall influenza vaccination
period, including 624 patients for whom influenza vaccine was indicated ...

The Health Belief Model: A Decade Later -
NK Janz, MH Becker - Health Education & Behavior, 1984 - heb.sagepub.com
Page 1. http://heb.sagepub.com Behavior Health Education & DOI: 10.1177/
109019818401100101 1984; 11; 1 Health Educ Behav Nancy K. Janz ...

Adverse reactions to influenza vaccine in elderly people: randomised double blind placebo controlled … -
TM Govaert, GJ Dinant, K Aretz, N Masurel, MJ … - BMJ: British Medical Journal, 1993 - pubmedcentral.nih.gov
... received influenza vaccine and 902 placebo. MAIN OUTCOME MEASURES--Adverse reactions
reported on postal questionnaire completed four weeks after vaccination. ...

Chronic stress alters the immune response to influenza virus vaccine in older adults -
JK Kiecolt-Glaser, R Glaser, S Gravenstein, WB … - Proc Natl Acad Sci US A, 1996 - pubmedcentral.nih.gov
... with a progressive dementia) is associated with an impaired immune response to
influenza virus vaccination, we compared 32 caregivers' vaccine responses with ...

Cost-Effectiveness of the Influenza Vaccine in a Healthy, Working-Age Population. -
DS Campbell, MH Rumley - Journal of Occupational and Environmental Medicine, 1997 - joem.org
... Hammond ML, Ferris AA, Faine S, McAvan T. Effective protection against influenza
after vaccination with subunit vaccine. Med J Aust. 1978;1:301-303. ...

Relation between Influenza Vaccination and Outpatient Visits, Hospitalization, and Mortality in … -
KL Nichol, L Baken, A Nelson - Annals of Internal Medicine, 1999 - annals.highwire.org
... 2 March 1999 | Volume 130 Issue 5 | Pages 397-403. Background: Influenza
vaccine is underused in groups targeted for vaccination. ...

Source: Google Scholar
 
 

Flu Vaccine Associated With Slight Increase In Risk Of Hospitalization For Neurological Disorder

Article Date: 16 Nov 2006 - 10:00am (PST)
Influenza vaccine is associated with a small but increased risk for hospitalization with the potentially debilitating neurological disorder known as Guillain-Barre syndrome, although the absolute risk associated with the vaccine is very low, according to a report in the November 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Guillain-Barre syndrome affects about one in 100,000 individuals per year, according to background information in the article. The disorder occurs when the body's immune system attacks part of the nervous system, causing weakness or tingling that can eventually worsen to paralysis. Previous reports have linked influenza vaccine to the development of Guillain-Barre syndrome, but uncertainty remains about the association.

David N. Juurlink, M.D., Ph.D., Institute for Clinical Evaluative Sciences (ICES), University of Toronto, Ontario, and colleagues studied residents of Ontario, Canada, where a universal influenza immunization program that provides free yearly vaccinations to all residents age 6 months or older was instituted in October 2000. First, the researchers identified all the cases of hospitalization for Guillain-Barre syndrome among Ontario residents age 18 and older between April 1, 1993, and March 31, 2004. They then identified which of those patients had received flu vaccines and compared their risk for hospitalization for Guillain-Barre syndrome within two to seven weeks after vaccination to the time period 20 to 43 weeks later. In a second analysis examining the total number of hospitalizations for Guillain-Barre syndrome in Ontario between 1991 and 2004, the investigators compared the numbers of cases before and after the immunization program began in 2000.

Article continues below and (thank you)
 
Between 1993 and 2004, the researchers identified 1,601 hospital admissions due to Guillain-Barre syndrome in Ontario, 269 of which occurred within 43 weeks of the patient receiving a vaccine in October or November (which was assumed to be an influenza vaccine). Patients were about one and a half times as likely to be hospitalized for Guillain-Barre syndrome in the two to seven weeks after vaccination than they were 20 to 43 weeks later. In the second analysis, the researchers looked at the 2,173 hospital admissions due to Guillain-Barre syndrome that occurred in Ontario between 1991 and 2004 (170 new cases per year, or about 14 cases per million persons per year). They did not find any significant difference in the rate of hospitalization for Guillain-Barre syndrome before and after the inception of the immunization program.

"Our results must be interpreted carefully," the authors write. "The increase in relative risk we observed corresponds to a very low absolute risk for Guillain-Barre syndrome, given the low baseline incidence of the disease (approximately one in 100,000 population). Furthermore, the lack of association on a population health level is consistent with the prevalent impression that influenza vaccine is only one of many potential causes of Guillain-Barre syndrome."
 
Because of the low overall risk for Guillain-Barre syndrome, physicians and patients should primarily consider the benefits of flu vaccines when making a decision about whether or not to get immunized. However, individuals who receive the shots should be told about the risk for Guillain-Barr頳yndrome and a surveillance strategy should be implemented as part of any mass vaccination program.

###

(Arch Intern Med. 2006;166:2217-2221.)

This study was sponsored in part by a grant from the Canadian Institutes of Health Research. Co-authors Drs. Juurlink and Wilson are supported by New Investigator Awards from the Canadian Institutes of Health Research. Dr. Juurlink is sponsored by the University of Toronto Drug Safety Research Group. Co-author Dr. Kwong is supported by a fellowship award from the Canadian Institutes of Health Research. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Contact: Julie Dowdie
JAMA and Archives Journals
 
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