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Recent News and Articles on the Keywords: bone cancer + cancer + out  Related to the article below (Last Update: 8/4/2008)

Sorting Out Coffee?s Contradictions
New York Times, United States -
And a study of 59000 women in Sweden found no connection between coffee, tea or caffeine consumption and breast cancer. Bone loss. ...
Kayak pair in Irish Sea trip to make splash for cancer victims
Scotsman, United Kingdom -
Mr Hay also knows how cancer can have an impact on the lives of teenagers after his mother's premature death from breast cancer 13 years ago. ...
New York Hospitals Are Maneuvering in War on Cancer
New York Sun, United States - Aug 3, 2008
Buoyed by scientific advances, academic medical centers increasingly are building and planning cancer centers, modern facilities featuring state-of-the-art ...

Winston-Salem Journal
The Battle Rages On: Family copes in different ways as son fights ...
Winston-Salem Journal, NC - Aug 3, 2008
But the anonymous donor's stem cells take root and begin to pump out cancer-free blood. In November, Chase poses for senior pictures, peeling off the thin ...
Determined to Beat the Disease
RedOrbit, TX - Aug 3, 2008
Having defeated that, she found out in April that she had bone cancer. However, the cancer has been confined to her right arm, and she can barely use it. ...
Tarrant County services provide hope in cancer battle
Fort Worth Business Press, TX -
She had a mastectomy and chemotherapy, but in 2003 it was confirmed that the cancer had spread to her bone marrow, liver and spleen. ...
Drug shows promise treating breast cancer
St. Louis Post-Dispatch,  United States -
Naughton said initial results of the Siteman study show Zometa helps decrease the number of cancer cells in the bone marrow of women with localized breast ...
Big Turnout For Little Boy Needing Bone Marrow Transplant
KLAS-TV, NV -
"We recently lost a young man from our congregation who was in line for a bone marrow transplant who was battling cancer and so Candle lighters contacted us ...

The Columbian
Blog details teen's cancer fight
The Columbian, WA - Aug 3, 2008
Since February, Elizabeth Rowan, 17, and her dad, Rod Rowan, have been blogging about her journey with osteosarcoma ? a type of bone cancer ? at ...
Searching for a match
News-Leader.com, MO -
Sean and Elena Stewart get up at sunrise every day to make the nearly one-hour trek to MD Anderson Cancer Center in Houston, Texas. ...
Source: Google News

A multigenic program mediating breast cancer metastasis to bone -
Y Kang, PM Siegel, W Shu, M Drobnjak, SM Kakonen, C … - Cancer Cell, 2003 - Elsevier
... Figure 3. A bone metastasis gene expression signatureA ... a previously identified
poor-prognosis breast cancer genes (van ... Data correspond to the 48 out of the 70 ...

… emission tomography for the detection of bone metastases in patients with non-small cell lung cancer -
T Bury, A Barreto, F Daenen, N Barthelemy, B Ghaye … - European Journal of Nuclear Medicine and Molecular Imaging, 1998 - Springer
... tive patients with histological diagnosis of non-small cell lung cancer (NSCLC)
who ... Radionu- clide bone scanning correctly identified 54 out of 89 ...

The detection of disseminated tumor cells in bone marrow from colorectal-cancer patients by a … -
E Soeth, C Roder, H Juhl, U Kruger, B Kremer, H … - Int J Cancer, 1996 - ncbi.nlm.nih.gov
... Investigation of bone-marrow specimens of patients with pancreatic cancer showed
that 4 out of 11 patients were positive for CK-20 mRNA. ...

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression … -
TR Golub, DK Slonim, P Tamayo, C Huard, M … - Science, 1999 - sciencemag.org
... We set out to develop a more systematic approach to ... such microarrays could provide
a tool for cancer classification ... data set consisted of 38 bone marrow samples ...

Gastric Cancer Originating from Bone Marrow-Derived Cells -
JM Houghton, C Stoicov, S Nomura, AB Rogers, J … - Science, 2004 - sciencemag.org
... of Helicobacter-mediated gastric cancer, dysplasia is ... Bone marrow?derived GIN displayed
features consistent ... epithelial phenotype, ruling out the unlikely ...

… tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases. -
K Pantel, J Izbicki, B Passlick, M Angstwurm, K … - Lancet, 1996 - ncbi.nlm.nih.gov
... pN(1-2)M(0)). Tumour cells in bone-marrow aspirates ... 215 patients without epithelial
cancer (ie, with benign epithelial tumours ... was found in each of 6 out of 215 ...

… in bone marrow in patients with primary breast cancer: evaluation as an early predictor of bone -
JL Mansi, U Berger, D Easton, T McDonnell, WH … - Br Med J (Clin Res Ed), 1987 - pubmedcentral.nih.gov
... micrometastases at presentation compared with only 41 out of 288 ... in a patient with
primary breast cancer is a useful predictor of early relapse in bone and may ...

Use of the Stromal Cell-derived Factor-1/CXCR4 Pathway in Prostate Cancer Metastasis to Bone 1 -
RS Taichman, C Cooper, ET Keller, KJ Pienta, NS … - Cancer Research, 2002 - AACR
... Prostate cancer cells may use CXCR4 receptors to adhere to cells and/or extracellular
matrix components in the bone marrow. We carried out experiments to test ...

Palliative pamidronate treatment in patients with bone metastases from breast cancer -
AT van Holten-Verzantvoort, HM Kroon, OL Bijvoet, … - Journal of Clinical Oncology, 1993 - jco.ascopubs.org
... pamidronate group, the occurrence of hypercalcemia, severe bone pain, and ... of pamidronate
caused a 23% drop-out rate, but other cancer-associated factors ...

Dissemination and growth of cancer cells in metastatic sites -
AF Chambers, AC Groom, IC MacDonald? - Nat Rev Cancer, 2002 - microarray1.princeton.edu
... where breast cancer metastases are often found ? bone, liver, brain ... How efficient
are capillaries at ?filtering?out these circulating cancer cells? ...

Source: Google Scholar
 
 

Drug Might Squeeze Out Bone Cancer

November 16, 2006 03:58:06 PM PST

THURSDAY, Nov. 16 (HealthDay News) -- An experimental drug prevented bone tumors in 50 percent of mice in a preclinical study, researchers report.

The results suggest this treatment may be able to prevent or treat metastatic tumors in bone, say scientists at the University of Texas M.D. Anderson Cancer Center.

They determined the drug, known as VEGF121/rGel, stopped specialized cells within the bone from destroying material to make room for embedded prostate tumors. The drug may also inhibit the growth of blood vessels that feed bone tumors.

The findings appear in the current issue of Cancer Research.

If VEGF121/rGel can stop the growth of human prostate cancer cells in the bones of mice, it may also be able to halt the growth of other kinds of cancers in bones, the team noted.

"Many tumors invade bone in the same way, so these findings suggest it may be possible to shut down this process regardless of the tumor type," study author Michael G. Rosenblum, a professor in the department of experimental therapeutics, said in a prepared statement.

"If that could be done -- and we are a long way from determining if it is possible -- we may be able to offer the first treatment that specifically targets bone metastasis," he said.

Article continues below and (thank you)

 

Phase I human clinical trials of VEGF121/rGel are expected to begin soon at M.D. Anderson Cancer Center.

More information

The American Cancer Society has more about bone cancer.

 
 
 
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