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Recent News and Articles on the Keywords: mri + heart + early  Related to the article below (Last Update: 8/4/2008)


Ottawa Citizen
Showing entries for Category: Get-Well-Soon
Examiner.com - Aug 3, 2008
Benefiting from early detection through a doctor ordered MRI, the cancer is not life threatening. Christina is following the recommended treatment of her ...
AssociatedPress
all 970 news articles »

Ken Davidoff's baseball insider
It's a gut-check week for our two locals
Ken Davidoff's baseball insider, NY -
As the regulars here know, I generally loathe talk about "heart, grid and guts," as our man Dennis puts it. But I don't see how you can avoid it this week, ...
Alzheimer Disease Plaques Seen With Conventional MRI in Animal ...
MarketWatch - Jul 27, 2008
Two other studies reported at ICAD 2008 use MRI and advanced computer analysis to bring us closer to early identification of Alzheimer's, perhaps even ...
Cards' Boldin to have MRI on hamstring
Houston Chronicle, United States - Jul 31, 2008
?I still very much love it in my heart. I still feel like I can compete at a Pro Bowl level, but the situation is going to have to be right. ...
Health Front and Center
Publishers Weekly, NY -
Another wrenching personal account can be found in Measure of the Heart: A Father's Alzheimer's, A Daughter's Return by Mary Ellen Geist, coming this month ...
Lunch with Heather Perry
ScienceBlogs -
In fact, Pete now has doctors down in Mexico who will do the operation, and they take MRI scans pre- and post-trepanation. After the operation the ratio of ...
This Week in Health
Intelihealth.com, PA - Aug 1, 2008
We also look at a promising experimental Alzheimer's drug and at why some doctors say kids don't need a heart test before starting ADHD medications. ...
Exercise Stops Brain Shrinking in Alzheimer's Patients The Money Times
Fit body can mean a fit brain Milwaukee Journal Sentinel
all 678 news articles »
Jury Rejects Claims of $23 Million in Unusual No-Fault Case
Law.com (subscription), CA - Aug 1, 2008
The industry standard for MRI payment is $900. The jury's verdict disallowed collection of any of those claims, finding that the corporation rather than ...
Do economists need brains?
Economist, UK - Jul 24, 2008
Neuroeconomists have tried to explain this seemingly irrational behaviour by using an ?active MRI?. In MRIs used in medicine the patient simply lies still ...

Times Online
Is the law bleeding the NHS to death?
Times Online, UK - Aug 2, 2008
It means a plethora of clinically unnecessary, just-in-case blood tests, x-rays, endoscopic examinations, CT and MRI scans, avoidance of tricky procedures, ...
Source: Google News

Early Contrast-Enhanced MRI Predicts Late Functional Recovery After Reperfused Myocardial Infarction -
WJ Rogers, CM Kramer, G Geskin, YL Hu, TM Theobald … - Circulation, 1999 - Am Heart Assoc
... 7 8 Using an isolated rabbit heart preparation, Kim et al 15 quantified MRI contrast
uptake ... intensity ratios compared with REMOTE during the early wash-in ...

… Middle Cerebral Artery Stroke as Defined by Early Diffusion-Weighted and Perfusion-Weighted MRI -
G Rordorf, WJ Koroshetz, WA Copen, SC Cramer, PW … - Stroke, 1998 - Am Heart Assoc
... in Lesion Growth from Early Apparent Diffusion ... Radiology of the American Heart
Association Stroke ... and Diffusion- and Perfusion-Weighted MRI Abnormalities in 117 ...

Guidelines for the Early Management of Patients With Ischemic Stroke 2005 Guidelines Update A … -
H Adams, R Adams, G Del Zoppo, LB Goldstein - Stroke, 2005 - Am Heart Assoc
... of the American Heart Association. Stroke. 2003; 34: 1084?1104. [Free Full Text];
Kidwell CS, Chalea JA, Saver JL, Davis SM, Warach S. Hemorrhage early MRI ...

An MRI Study of Neurological Injury Before and After Congenital Heart Surgery -
WT Mahle, F Tavani, RA Zimmerman, SC Nicolson, KK … - Circulation, 2002 - Am Heart Assoc
... used to gain insight into early neurological injury ... studies examining neonates with
congenital heart disease (CHD ... as opposed to magnetic resonance imaging (MRI). ...

Early childhood prolonged febrile convulsions, atrophy and sclerosis of mesial structures, and … -
F Cendes - Neurology, 1993 - AAN Enterprises
... HO-1 overexpression Am J Physiol Heart Circ Physiol ... A. Canady, and C. Watson Volumetric
MRI, pathological, and ... Santos, AY Mian, and AJ Cole Early-life seizures ...

MRI and neuropsychological differences in early-and late-life-onset geriatric depression -
S Salloway - Neurology, 1996 - AAN Enterprises
... Performance in the Framingham Heart Study Psychosom ... in depression: late- and
early-onset illness ... R. Nakra The Relationship of MRI Subcortical Hyperintensities ...

Early Assessment of Myocardial Salvage by Contrast-Enhanced Magnetic Resonance Imaging -
HB Hillenbrand, RJ Kim, MA Parker, DS Fieno, RM … - Circulation, 2000 - Am Heart Assoc
... wall motion and myocardial salvage in early experimental acute ... Am Heart J.
1984;107:13?19.[Medline ... Contrast enhanced MRI of myocardium at risk: distinction ...

… cardiac contraction in humans mapped by high-temporal-resolution MRI tagging: early onset and late … -
JJM Zwanenburg, MJW Gotte, JPA Kuijer, RM Heethaar … - … Journal of Physiology- Heart and Circulatory Physiology, 2004 - Am Physiological Soc
... of shortening and peak shortening are early in the ... contraction times in the normal
human heart may give ... method for fast acquisition of MRI myocardial tagging ...

Imaging heart motion using harmonic phase MRI -
NF Osman, ER McVeigh, JL Prince - Medical Imaging, IEEE Transactions on, 2000 - ieeexplore.ieee.org
... used images generated by a simulation program designed in our laboratory, an early
version of ... OSMAN et al.: IMAGING HEART MOTION USING HARMONIC PHASE MRI ...

Early Diagnosis of Cerebral Fat Embolism Syndrome by Diffusion-Weighted MRI (Starfield Pattern) -
PM Parizel, HE Demey, G Veeckmans, F Verstreken, P … - Stroke, 2001 - Am Heart Assoc
... 32:2942.) ? 2001 American Heart Association, Inc. Case Reports. Early Diagnosis
of Cerebral Fat Embolism Syndrome by Diffusion-Weighted MRI (Starfield Pattern). ...

Source: Google Scholar
 
 

MRI Detects Early Heart Damage In Patients With Sarcoidosis

Article Date: 15 Nov 2006 - 9:00am (PST)
To detect heart damage early in patients with the immune system disorder sarcoidosis, who are at elevated risk of dieing from heart problems, magnetic resonance imaging is twice as sensitive as conventional methods, according to a study by Duke University Medical Center cardiologists.

By using magnetic resonance imaging, or MRI, to discover minute areas of heart damage before they grow larger, physicians may be able to take action to prevent sudden cardiac death, which is a leading cause of death in patients with sarcoidosis, the researchers said.

Sarcoidosis is characterized by the formation of tiny inflammatory growths called granulomas. Although granulomas tend to cluster in the lungs, in lymph nodes and under the skin, they also can form in the heart. When they do, it currently is difficult to determine which patients will develop heart damage, the researchers said.

"We found that MRI was sensitive in detecting small areas of damage in the hearts of patients with sarcoidosis, and we were further able to correlate these areas of damage with future adverse outcomes," said Duke cardiologist Manesh Patel, M.D., who presented the results of the study on Sunday, Nov. 12, at the annual scientific sessions of the American Heart Association, in Chicago. "The MRI technology is very good at obtaining high-resolution images of heart muscle and distinguishing normally functioning heart cells from those that are damaged or destroyed."

Article continues below and (thank you)
 
The study was supported by the Duke Cardiovascular Magnetic Resonance Center.

According to Patel, conventional methods identify cardiac damage in only 5 percent to 7 percent of sarcoidosis patients. The standard evaluation includes an electrocardiogram, which is an electrical test of the heart, coupled with one of a number of different cardiac imaging techniques.

But previous studies in which autopsies were performed on sarcoidosis patients indicate that up to 30 percent of such patients exhibit evidence of heart damage, he said.

"For this reason, we hypothesized that cardiac damage in sarcoidosis patients is more common and is often unrecognized, explaining why it could be a major cause of death in these patients," Patel said.

For their analysis, the Duke researchers identified 81 sarcoidosis patients consecutively referred for evaluation at Duke. All of the patients received a standard clinical evaluation including an electrocardiogram and on average 1.6 non-cardiac MRI imaging tests, and a cardiac MRI scan. The conventional method identified 10 patients (12.3 percent) with heart damage, while the cardiac MRI identified 21 patients (26 percent) with areas of heart damage, Patel said.

The damage observed often did not fit the pattern of damage caused by coronary artery disease, Patel said, a finding which suggested that the sarcoidosis was the cause of the damage.
 
The patients in the study were followed by their treating physicians for an average of 13 months, and Patel's team examined their records to see if they had died or had experienced medical problems related to the heart's electrical system.

According to Patel, it is commonly thought that when sarcoidosis damages a portion of heart muscle, the damaged areas can block or reroute the electrical impulses that keep the heart beating. Sudden cardiac death can occur when the heart's internal electrical system is disrupted, causing the heart to beat erratically and, in some cases, to stop.

By the end of the follow-up period, five patients had died from cardiac causes, two had experienced heart-beat abnormalities requiring treatment to bring the heart back into normal rhythm and one needed a pacemaker implanted to maintain normal heart rhythm, Patel said.

The imaging technique that the team used is called delayed enhancement cardiac MRI. In this approach, the researchers inject trace amounts of the element gandolinium into patients before administering the MRI scan.

"Gandolinium is an inert metal, and it cannot enter normally functioning heart muscle cells," Patel said. "However, if small areas of heart muscle are damaged, there are areas that absorb the gandolinium like a sponge. The MRI then detects where the gandolinium accumulates and shows us where the damage is located."

###

Other members of the research team were Peter Cawley, John Heitner, Igor Klem, Michele Parker, Trip Meine, Michael Elliott, Robert Judd and Raymond Kim.

Contact: Richard Merritt
Duke University Medical Center
 
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